MERLIN SIGNED
Multi-modal, multi-scale retinal imaging
Total Cost €
0EC-Contrib. €
0Partnership
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0MERLIN project word cloud
Explore the words cloud of the MERLIN project. It provides you a very rough idea of what is the project "MERLIN" about.
Project "MERLIN" data sheet
The following table provides information about the project.
| Coordinator |
IMAGINE EYES SA
Organization address contact info |
| Coordinator Country | France [FR] |
| Project website | https://www.imagine-eyes.com/merlin/ |
| Total cost | 5˙678˙335 € |
| EC max contribution | 4˙867˙660 € (86%) |
| Programme |
1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)) |
| Code Call | H2020-ICT-2017-1 |
| Funding Scheme | IA |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-12-01 to 2020-11-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | IMAGINE EYES SA | FR (ORSAY) | coordinator | 1˙891˙575.00 |
| 2 | ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM | NL (ROTTERDAM) | participant | 1˙072˙825.00 |
| 3 | MEDIZINISCHE UNIVERSITAET WIEN | AT (WIEN) | participant | 588˙025.00 |
| 4 | FUNDACIO INSTITUT DE CIENCIES FOTONIQUES | ES (Castelldefels) | participant | 522˙500.00 |
| 5 | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | FR (PARIS) | participant | 431˙000.00 |
| 6 | REGION HOVEDSTADEN | DK (HILLEROD) | participant | 361˙735.00 |
Map
Project objective
The ambition of the MERLIN project is to improve in-depth diagnosis and therapeutic follow-up of diseases that impact the eye’s retina. To do so, the MERLIN partners will deliver a novel medical imaging device able to detect pathological alterations in the retina with highly enhanced sensitivity and specificity. The medical applications of this device encompass a wide range of retinal pathologies, including age-related macular degeneration (AMD), as well as chronic vascular conditions, including diabetes. AMD and diabetic retinopathy (DR) are the leading cause of blindness worldwide in people over 55 years of age. Such diseases slowly develop at the microscopic scale in the retina. Using current imaging techniques, it is difficult to detect them at early stage, and it often takes months to assess the effects of treatments. These limitations hinders both the clinical management of patients and the investigation of new therapies. In order to overcome these issues, the device developed in MERLIN will for the first time enable doctors to examine the retina with multiple imaging modalities at both the macroscopic and microscopic scales. Modalities will include ultrafast scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography (OCT-A), while ultrahigh resolution will be provided by adaptive optics technology. This unique combination will reveal previously invisible cellular and microvascular retinal detail in 3 dimensions. The project partners will also develop advanced image processing software for the visualization and quantitative analysis of microscopic structures, and conduct experimentations to optimize and validate performance in AMD and DR patients. As the feasibility of this diagnostic approach has previously been demonstrated in another European R&D project (FP7 FAMOS, 2012-2017), MERLIN will translate the technology from a preexisting laboratory prototype to a nearly commercial device usable in clinical trials.
Deliverables
| Linkedin, facebook and twitter accounts created | Websites, patent fillings, videos etc. | 2020-04-14 17:05:56 |
Take a look to the deliverables list in detail: detailed list of MERLIN deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Luisa Sánchez Brea, Danilo Andrade De Jesus, Muhammad Faizan Shirazi, Michael Pircher, Theo van Walsum, Stefan Klein Review on Retrospective Procedures to Correct Retinal Motion Artefacts in OCT Imaging published pages: 2700, ISSN: 2076-3417, DOI: 10.3390/app9132700 |
Applied Sciences 9/13 | 2020-04-14 |
| 2018 |
Matthias Salas, Marco Augustin, Franz Felberer, Andreas Wartak, Marie Laslandes, Laurin Ginner, Michael Niederleithner, Jason Ensher, Michael P. Minneman, Rainer A. Leitgeb, Wolfgang Drexler, Xavier Levecq, Ursula Schmidt-Erfurth, Michael Pircher Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye published pages: 1871, ISSN: 2156-7085, DOI: 10.1364/BOE.9.001871 |
Biomedical Optics Express 9/4 | 2020-04-14 |
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