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Mechanisms of K stable isotope fractionation in vertebrates and significance to their energy metabolism

Total Cost €


EC-Contrib. €






 BioIsoK project word cloud

Explore the words cloud of the BioIsoK project. It provides you a very rough idea of what is the project "BioIsoK" about.

reared    cycling    thermo    physiological    thermophysiology    class    inductively    ms    constitute    ca    turned    unprecedented    apprehending    phylogenetic    metabolism    classes    fossil    zn    metals    coupled    bioessential    principally    vertebrates    inherent    plasma    isotope    proteus    group    advent    behavioral    icp    unexplored    origins    body    prototype    mechanisms    driving    ratios    mc    perspectives    rates    democratization    species    spectrometers    energy    otherwise    compositions    dependent    itself    technologies    first    ecological    fisher    intensity    inaccessible    ecosystems    biodiversity    notably    varying    precious    cell    assets    evolution    collision    unraveling    reaction    fe    elliott    dynamics    extinct    functions    isotopes    natural    reg    tissues    fairly    potassium    collector    metabolic    biological    vertebrate    organisms    mass    modern    opened    tim    spectrometry    reconstruction    hindrances    mg    stable    traits    metal    later    cu   

Project "BioIsoK" data sheet

The following table provides information about the project.


Organization address
postcode: BS8 1QU

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF BRISTOL UK (BRISTOL) coordinator 183˙454.00


 Project objective

The reconstruction of physiological and ecological traits of extinct organisms is crucial for apprehending the dynamics of the evolution of species and ecosystems as well as the origins of modern biodiversity. The recent advent of the use of natural stable isotopes of bioessential metals is principally related to the democratization of multi-collector inductively coupled plasma mass spectrometers (MC-ICP-MS). These isotope systems (Mg, Ca, Cu, Fe or Zn) opened up unprecedented perspectives for the study of their cycling in past and present vertebrate organisms and turned out to be precious assets for the unraveling of otherwise inaccessible biological features of fossil organisms, being ecological, behavioral or physiological characteristics. Potassium (K) is a bioessential metal in all vertebrates, where its cycling intensity is notably dependent on their metabolic rates, the later varying itself with thermophysiology from a phylogenetic class to another or with body mass within a given class. Due to its crucial biological functions as well as the observed significant effects of biological processes on its isotope ratios, K isotopes constitute a highly promising novel isotope system for the study of vertebrate metabolism. However, the K stable isotope compositions of vertebrate tissues are currently fairly unexplored, notably due to major technical hindrances, inherent to the existing mass spectrometry technologies. This project aims first to develop a reliable method of K stable isotope analysis using the state-of-the-art “Proteus” prototype MC-ICP-MS implemented with the collision-reaction cell technology and developed by Tim Elliott group and Thermo Fisher®. This method will then be used for analysis of tissues from vertebrates of various classes reared in controlled conditions. This will allow identifying the main mechanisms driving the isotope compositions of vertebrate tissues and assess their potential for the study of vertebrates energy metabolism.

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The information about "BIOISOK" are provided by the European Opendata Portal: CORDIS opendata.

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