Opendata, web and dolomites

NLR_NLR-ID power SIGNED

NLR-ID diversity, mechanism and functionality upon transfer between species

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 NLR_NLR-ID power project word cloud

Explore the words cloud of the NLR_NLR-ID power project. It provides you a very rough idea of what is the project "NLR_NLR-ID power" about.

taxonomic    fellowship    infection    resistance    maximizing    full    function    innate    binding    effectors    rrs1    diverse    serve    species    requirement    wheat    closely    confers    receptor    pathogen    fungal    that    recognition    outcomes    sequence    completely    disease    class    goals    bioinformatics    solanaceae    animal    transfer    repertoires    bacterial    insights    detect    arise    cucurbit    ids    pathogens    prr    nlrs    carry    receptors    linked    barley    resistant    intracellular    discover    nlr    pair    appropriate    proteins    confer    molecular    functional    rps4    helper    plants    profound    interdisciplinary    cell    pattern    plant    families    host    interactions    capture    leucine    baits    repeat    transgenic    basis    genotypes    poaceae    rusts    restricted    dna    lines    usually    surface    diversity    id    immune    transferred    arabidopsis    diseases    defences    pairs    effector    head    rice    hypothesis    gene    domains    action    nucleotide    activate   

Project "NLR_NLR-ID power" data sheet

The following table provides information about the project.

Coordinator
THE SAINSBURY LABORATORY 

Organization address
address: Norwich Research Park, Colney Lane
city: NORWICH
postcode: NR47UH
website: http://www.tsl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-05-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE SAINSBURY LABORATORY UK (NORWICH) coordinator 195˙454.00

Map

 Project objective

Plant and animal innate immune systems detect pathogen infection by both cell-surface PRR (pattern recognition receptor) and intracellular NLR (nucleotide-binding leucine-rich repeat) immune receptors, and activate effective defences. Transfer of cell surface receptors between plant families can enhance disease resistance, but intracellular receptors are often non-functional when transferred to different families. This 'restricted taxonomic functionality' may arise from a requirement for an appropriate helper or partner NLR. Some NLRs carry Integrated Domains (IDs) that serve as “baits” that detect the action of pathogen effector proteins, thus enabling pathogen recognition. NLR-ID proteins require for function a helper NLR, usually closely linked as a head-to-head gene pair. Some NLR/NLR-ID pairs confer resistance to diverse pathogens when transferred as a unit between plant families. For example, Arabidopsis RPS4/RRS1, when transferred as a unit, confers recognition of bacterial and fungal pathogens in Solanaceae and cucurbit plants. This project is based on the hypothesis that NLR/NLR-ID pairs from one species can detect effectors that target that class of ID from a pathogen of any species. Rice is completely resistant to fungal rusts of wheat and barley. Many NLR-IDs are present in rice but not in other Poaceae. My goals are to: (i) use DNA sequence capture and bioinformatics to discover the full NLR/NLR-ID pair repertoires of diverse rice genotypes; (ii) investigate rice IDs interactions with effectors from wheat and barley pathogens; and (iii) transfer gene pairs to barley, maximizing the diversity of IDs in these pairs, and assess transgenic lines for novel resistance to barley diseases. The outcomes of this interdisciplinary Fellowship will provide profound insights into NLR/NLR-ID diversity in plants, into the diversity of domains that are effector targets, and into the molecular basis of 'non-host' disease resistance.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NLR_NLR-ID POWER" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "NLR_NLR-ID POWER" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

Widow Spider Mating (2020)

Immature mating as a novel tactic of an invasive widow spider

Read More  

LieLowerBounds (2019)

Lower bounds for partial differential operators on compact Lie groups

Read More  

TARGET SLEEP (2020)

Boosting motor learning through sleep and targeted memory reactivation in ageing and Parkinson’s disease

Read More