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Ring-STORM SIGNED

Mechanically-Interlocked Ring-on-Thread Molecules for Super-Resolution Imaging

Total Cost €

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EC-Contrib. €

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Partnership

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 Ring-STORM project word cloud

Explore the words cloud of the Ring-STORM project. It provides you a very rough idea of what is the project "Ring-STORM" about.

molecular    supramolecular    ring    fulfilment    cnrs    methodology    efficient    nanoscopic    rotaxanes    expertise    give    spectroscopic    science    time    machines    light    optique    overcoming    cells    living    training    blink    electron    eacute    reconstruction    architectures    limit    ism    fellow    lp2n    molecule    conceptually    steady    resolved    interdisciplinary    receive    enhanced    assure    infrastructure    synthetic    packages    des    mol    transfer    stochastic    functional    scattering    sciences    photoactive    bordeaux    genetically    independence    encoded    culaires    patenting    constraints    techniques    proteins    communication    storm    iogs    practically    organic    imaging    photochemistry    microscopy    chemistry    undertaken    groups    super    expects    photophysics    synergistic    professional    career    skills    autonomous    spectroscopies    institut    institutes    overexpressing    maturity    inherent    univ    made    independent    single    fluorescence    resolution    unprecedented    modulate    optical    spain       photo    specialist    innovation    french    localization    fluorescent   

Project "Ring-STORM" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-15   to  2020-10-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

This interdisciplinary project focuses on the development of unprecedented autonomous novel photoactive nanoscopic molecular machines that “blink” for fluorescence microscopy imaging with a resolution higher than the light scattering limit. Its use in super-resolution imaging will represent a major innovation in imaging, both conceptually and practically, overcoming many inherent constraints associated with current techniques. By applying steady-state and time-resolved spectroscopies, photo-induced electron transfer will be used in these autonomous [2]rotaxanes to modulate fluorescence, and studies down to the single-molecule level (based on Stochastic Optical Reconstruction Microscopy) will be undertaken to achieve a new localization microscopy method ('Ring-STORM') adapted for living cells, without the need for overexpressing genetically encoded fluorescent proteins. The project will be developed at leading French research institutes, Institut des Sciences Moléculaires (ISM) and Institut d'Optique (LP2N-IOGS) both at the CNRS/Univ. Bordeaux. The fellow, a specialist in synthetic organic and supramolecular chemistry from Spain, will receive via the project training in molecular photochemistry/photophysics and super-resolution fluorescence imaging, providing him the necessary skills to design, develop and study novel tailored-made functional supramolecular architectures with enhanced spectroscopic properties. For this, the project is organized in synergistic work packages to assure efficient coordination and management, career development and training, science development, communication and technology transfer by patenting the new super-resolution imaging methodology that Ring-STORM expects to develop. This will give him independence and professional maturity towards an independent research career. The experience of the fellow, the expertise of the research groups, the infrastructure and equipment will assure the fulfilment of the project objectives.

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The information about "RING-STORM" are provided by the European Opendata Portal: CORDIS opendata.

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