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Ring-STORM SIGNED

Mechanically-Interlocked Ring-on-Thread Molecules for Super-Resolution Imaging

Total Cost €

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EC-Contrib. €

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Partnership

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 Ring-STORM project word cloud

Explore the words cloud of the Ring-STORM project. It provides you a very rough idea of what is the project "Ring-STORM" about.

proteins    assure    made    overexpressing    eacute    constraints    enhanced    professional    chemistry    reconstruction    efficient    fluorescence    receive    spain    career    inherent    cells    give    molecular    communication    maturity    packages    steady    time    groups    modulate    ism    skills    molecule    living    storm    innovation    single    overcoming    institut    functional    resolution    photochemistry    undertaken    mol    localization    iogs    des    architectures    patenting    institutes    univ    electron    supramolecular    independent    methodology    rotaxanes    resolved    spectroscopic    cnrs    science    interdisciplinary    independence    expects    sciences    photoactive    transfer    specialist    fluorescent    machines    optical    unprecedented    microscopy    lp2n    photophysics    photo    scattering    nanoscopic    fulfilment    techniques    encoded    culaires    spectroscopies    stochastic    light       blink    fellow    optique    bordeaux    infrastructure    organic    limit    french    imaging    synthetic    ring    expertise    conceptually    super    practically    training    synergistic    genetically    autonomous   

Project "Ring-STORM" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-15   to  2020-10-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

This interdisciplinary project focuses on the development of unprecedented autonomous novel photoactive nanoscopic molecular machines that “blink” for fluorescence microscopy imaging with a resolution higher than the light scattering limit. Its use in super-resolution imaging will represent a major innovation in imaging, both conceptually and practically, overcoming many inherent constraints associated with current techniques. By applying steady-state and time-resolved spectroscopies, photo-induced electron transfer will be used in these autonomous [2]rotaxanes to modulate fluorescence, and studies down to the single-molecule level (based on Stochastic Optical Reconstruction Microscopy) will be undertaken to achieve a new localization microscopy method ('Ring-STORM') adapted for living cells, without the need for overexpressing genetically encoded fluorescent proteins. The project will be developed at leading French research institutes, Institut des Sciences Moléculaires (ISM) and Institut d'Optique (LP2N-IOGS) both at the CNRS/Univ. Bordeaux. The fellow, a specialist in synthetic organic and supramolecular chemistry from Spain, will receive via the project training in molecular photochemistry/photophysics and super-resolution fluorescence imaging, providing him the necessary skills to design, develop and study novel tailored-made functional supramolecular architectures with enhanced spectroscopic properties. For this, the project is organized in synergistic work packages to assure efficient coordination and management, career development and training, science development, communication and technology transfer by patenting the new super-resolution imaging methodology that Ring-STORM expects to develop. This will give him independence and professional maturity towards an independent research career. The experience of the fellow, the expertise of the research groups, the infrastructure and equipment will assure the fulfilment of the project objectives.

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The information about "RING-STORM" are provided by the European Opendata Portal: CORDIS opendata.

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