Opendata, web and dolomites

RE-IMMUNE SIGNED

Intelligent Nano-encapsuled siRNA for Restoring Immune Cell Response to Cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 RE-IMMUNE project word cloud

Explore the words cloud of the RE-IMMUNE project. It provides you a very rough idea of what is the project "RE-IMMUNE" about.

expertise    shift    immunoediting    strategies    intracellular    group    efficient    scientific    leads    immune    rome    drawbacks    cancer    dna    sensing    combining    backgrounds    caruso    nanomaterials    trafficking    therapeutic    clinicians    edge    risk    thanks    time    nanodevices    groundbreaking    safe    msc    ricci    acquire    vergata    complementary    sirna    biomedicine    protect    melbourne    treatment    hands    accomplishing    idea    competences    expert    fellowship    young    combine    scientists    tumor    synergic    gain    forefront    nanomedicine    independence    re    microscopy    anti    cells    site    merge    diversify    tumoral    pro    contribution    vivo    intelligent    naked    genes    microenvironment    mechanisms    frank    encapsulated    francesco    cutting    nanomaterial    nano    effect    action    nucleic    acid    nanoscopy    why    prof    interdisciplinary    drug    silencing    university    fundamentally    world    foundation    tor    recognition    dynamic    immunotherapy    nanotechnology    cocktail    skills    met    overcome    until    training   

Project "RE-IMMUNE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA 

Organization address
address: VIA CRACOVIA 50
city: ROMA
postcode: 133
website: www.uniroma2.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 250˙518 €
 EC max contribution 250˙518 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2019
 Duration (year-month-day) from 2019-02-18   to  2022-02-17

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA IT (ROMA) coordinator 250˙518.00
2    UNIVERSITY OF MELBOURNE AU (MELBOURNE) partner 0.00

Map

 Project objective

WHY: To effectively bring siRNA-based therapeutic for cancer immunotherapy into the hands of clinicians requires the development of fundamentally new mechanisms to overcome current drawbacks. Accomplishing this will enable more efficient treatment with less side effects. WHAT: RE-IMMUNE is an interdisciplinary programme in which the field of nanomaterial and nucleic acid nanotechnology merge to develop intelligent nano- encapsulated siRNA for safe and efficient delivery of siRNA in cancer-associated immune cells, to re-program and shift the tumor microenvironment from pro to anti-tumoral. To achieve this goal, I will undertake a high risk/high gain programme at the forefront of nanomedicine. The leading idea is to overcome the drawbacks of naked siRNA by combining two synergic strategies that will protect siRNA until recognition of its target site. I will evaluate intracellular trafficking of siRNA nanodevices and the silencing effect. I will also investigate possible synergic effect of a siRNA cocktail able to target different genes at the same time. Finally, I will evaluate the re-immunoediting action in vivo. HOW: The challenge met by the proposed program is to provide a groundbreaking contribution to cancer treatment. To achieve these objectives, I will combine the different scientific backgrounds and expertise of two leading scientists. Prof. Frank Caruso (University of Melbourne) is a world-wide recognized expert on nanomaterials and biomedicine, and Prof. Francesco Ricci (University of Rome Tor Vergata) leads a young and dynamic group at the forefront of DNA nanotechnology for sensing and drug-delivery applications. The fellowship will proceed through a well-defined set of research and training tasks. Thanks to this MSC Fellowship, I will diversify my scientific knowledge and acquire cutting-edge competences (in nanomaterials, microscopy, and nanoscopy), as well as complementary skills, which will become the foundation of my scientific independence.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "RE-IMMUNE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "RE-IMMUNE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

PHOTOCARBOX (2020)

Increasing the scope of CO2-utilising photoreactions: asymmetric photosynthesis of amino acids

Read More  

QuanToPol (2020)

Quantum Topological Polaritonics

Read More  

STOPFIRE (2019)

Emergency Decision Support System of Offshore Platform Fires

Read More