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ACDC SIGNED

Artificial Cells with Distributed Cores to Decipher Protein Function

Total Cost €

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EC-Contrib. €

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Partnership

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 ACDC project word cloud

Explore the words cloud of the ACDC project. It provides you a very rough idea of what is the project "ACDC" about.

embodiment    health    dimensions    dna    resonators    diverse    communication    union    bioremediation    vision    secondary    compounds    commercial    actuation    compartmental    integration    cores    assembly    microfluidics    reconfigurable    performance    workplan    ethical    re    core    sensing    economic    framework    first    membrane    microscale    construct    disease    gene    threat    building    bioagent    cell    architectures    bio    mathematical    cells    international    public    toward    engagement    creation    sectors    generation    enterprise    constructs    cellular    intellectual    integrating    industry    responsive    assembled    team    vitro    advantage    liquid    envision    translation    theranostics    precision    55    technologies    interdisciplinary    miniaturization    apps    expression    collective    functional    property    acdc    inter    living    personalized    microwave    environments    technological    hierarchical    configurable    outreach    compartmentalisation    platform    concentrating    academia    channels    finds    organelles    programmable    artificial    detection    chip    job    mobile    lab    metabolism    supramolecular    wetware       heavily    start    demand    exemplars    tissues    class    nontrivial    recapitulates    chemical    valuable    explore    medicine   

Project "ACDC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TRENTO 

Organization address
address: VIA CALEPINA 14
city: TRENTO
postcode: 38122
website: www.unitn.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 4˙376˙295 €
 EC max contribution 4˙376˙295 € (100%)
 Programme 1. H2020-EU.1.2.2. (FET Proactive)
 Code Call H2020-FETPROACT-2018-01
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2023-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TRENTO IT (TRENTO) coordinator 1˙198˙437.00
2    CARDIFF UNIVERSITY UK (CARDIFF) participant 1˙144˙596.00
3    EXPLORA SRL IT (ROMA) participant 729˙500.00
4    ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN CH (WINTERTHUR) participant 630˙550.00
5    ELVESYS FR (PARIS) participant 512˙125.00
6    MUSEO DELLE SCIENZE IT (TRENTO) participant 161˙086.00

Map

 Project objective

We envision a future where ‘chemical apps’ on mobile devices produce on demand valuable compounds for health and performance as well as apps for bioagent threat detection and disease. To take concrete and defined steps toward this future vision, we will exploit the miniaturization provided by lab on a chip technology and construct responsive architectures and metabolism based on living cells and tissues. We will build programmable and re-configurable, (bio)chemical processes, with precision, order, and as hierarchical cellular constructs, in the same way as living systems. We will enable microscale, liquid-based, chemical compartmentalisation (cores), and inter-compartmental (core-core) communication, just as one finds in organelles, cells and tissues. ACDC will focus on developing this next generation technology through a detailed workplan that heavily involves the nontrivial tasks of integrating diverse state of the art technologies including microfluidics, microwave resonators, DNA-based supramolecular assembly, in vitro gene expression and the integration of membrane channels into a functional platform. In a future embodiment of this project, artificial cell technology will be used as programmable and reconfigurable matter for specific applications, including theranostics and personalized medicine as well as sensing and actuation in the environments for bioremediation. As the first steps towards that future vision, we aim to produce an artificial technological construct and process that recapitulates some aspects of living systems on the microscale, and therefore this project will produce exemplars of secondary living technologies concentrating on the wetware class [1] but also a multi-level mathematical framework. We have assembled an international, interdisciplinary team from academia, industry and public engagement. Our outreach and engagement programme will define the impact in both the public and economic sectors with ethical dimensions considered. Further, building upon 55 years of collective start-up enterprise experience, we will explore the translation of new intellectual property generated into commercial advantage and job creation for the European Union.

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The information about "ACDC" are provided by the European Opendata Portal: CORDIS opendata.

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