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ACDC SIGNED

Artificial Cells with Distributed Cores to Decipher Protein Function

Total Cost €

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EC-Contrib. €

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Partnership

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 ACDC project word cloud

Explore the words cloud of the ACDC project. It provides you a very rough idea of what is the project "ACDC" about.

bio    integrating    55    translation    construct    cellular    expression    assembly    diverse    interdisciplinary    reconfigurable    creation    compartmentalisation    concentrating    outreach    channels    compounds    advantage    embodiment    platform    responsive    lab    membrane    configurable    envision    demand    valuable    toward    chip    inter    core    intellectual    compartmental    property    disease    economic    recapitulates    microfluidics    performance    hierarchical    industry    finds    environments    cells    job    dimensions    academia    microwave    organelles    nontrivial    commercial    microscale    communication    international    vision    living    re    team    assembled    gene    mathematical    chemical    actuation    cell    acdc    sensing    theranostics    generation    workplan    exemplars    public    health    detection    explore    class    artificial    functional    threat    building    framework    engagement    architectures    cores    heavily    enterprise    mobile    first    miniaturization    liquid    resonators    sectors    technologies    vitro       technological    tissues    medicine    union    bioagent    metabolism    collective    ethical    bioremediation    personalized    constructs    integration    precision    supramolecular    dna    start    secondary    apps    programmable    wetware   

Project "ACDC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TRENTO 

Organization address
address: VIA CALEPINA 14
city: TRENTO
postcode: 38122
website: www.unitn.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 4˙376˙295 €
 EC max contribution 4˙376˙295 € (100%)
 Programme 1. H2020-EU.1.2.2. (FET Proactive)
 Code Call H2020-FETPROACT-2018-01
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2023-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TRENTO IT (TRENTO) coordinator 1˙198˙437.00
2    CARDIFF UNIVERSITY UK (CARDIFF) participant 1˙144˙596.00
3    EXPLORA SRL IT (ROMA) participant 729˙500.00
4    ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN CH (WINTERTHUR) participant 630˙550.00
5    ELVESYS FR (PARIS) participant 512˙125.00
6    MUSEO DELLE SCIENZE IT (TRENTO) participant 161˙086.00

Map

 Project objective

We envision a future where ‘chemical apps’ on mobile devices produce on demand valuable compounds for health and performance as well as apps for bioagent threat detection and disease. To take concrete and defined steps toward this future vision, we will exploit the miniaturization provided by lab on a chip technology and construct responsive architectures and metabolism based on living cells and tissues. We will build programmable and re-configurable, (bio)chemical processes, with precision, order, and as hierarchical cellular constructs, in the same way as living systems. We will enable microscale, liquid-based, chemical compartmentalisation (cores), and inter-compartmental (core-core) communication, just as one finds in organelles, cells and tissues. ACDC will focus on developing this next generation technology through a detailed workplan that heavily involves the nontrivial tasks of integrating diverse state of the art technologies including microfluidics, microwave resonators, DNA-based supramolecular assembly, in vitro gene expression and the integration of membrane channels into a functional platform. In a future embodiment of this project, artificial cell technology will be used as programmable and reconfigurable matter for specific applications, including theranostics and personalized medicine as well as sensing and actuation in the environments for bioremediation. As the first steps towards that future vision, we aim to produce an artificial technological construct and process that recapitulates some aspects of living systems on the microscale, and therefore this project will produce exemplars of secondary living technologies concentrating on the wetware class [1] but also a multi-level mathematical framework. We have assembled an international, interdisciplinary team from academia, industry and public engagement. Our outreach and engagement programme will define the impact in both the public and economic sectors with ethical dimensions considered. Further, building upon 55 years of collective start-up enterprise experience, we will explore the translation of new intellectual property generated into commercial advantage and job creation for the European Union.

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The information about "ACDC" are provided by the European Opendata Portal: CORDIS opendata.

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