Opendata, web and dolomites

EvoLucin SIGNED

400 Million Years of Symbiosis: Host-microbe interactions in marine lucinid clams from past to present

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 EvoLucin project word cloud

Explore the words cloud of the EvoLucin project. It provides you a very rough idea of what is the project "EvoLucin" about.

juveniles    outstanding    free    lucinidae    ancient    housed    edge    diversity    staggering    insights    animal    mechanisms    animals    experimental    symbiont    nature    tools    alter    discovering    combine    environment    communication    immense    trillions    cutting    experimentally    emergence    microbes    parts    immune    encoded    ideal    molecular    select    symbiotic    specificity    marine    interaction    distant    cells    lucinid    gill    found    perpetuation    families    virtually    exchange    acquisition    clams    chemosynthetic    biology    bacteria    recognition    raised    exclusive    microbe    interactions    symbionts    association    hypothesize    oceans    400    lab    history    basis    intracellular    unmatched    maintenance    infected    host    health    bacterial    evolutionary    limited    fundamentally    understand    function    underlying    transforming    innate    symbiosis    evolution    drive    proteins    earth    million    organ    location    few    overarching    species    lifetimes    microbial    lived    considering    infection    clam    assumptions   

Project "EvoLucin" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT WIEN 

Organization address
address: UNIVERSITATSRING 1
city: WIEN
postcode: 1010
website: www.univie.ac.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 1˙499˙561 €
 EC max contribution 1˙499˙561 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2024-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT WIEN AT (WIEN) coordinator 1˙499˙561.00

Map

 Project objective

The widespread recognition that interactions with microbes drive animal health, development and evolution is transforming biology, but we so far understand the underlying mechanisms in very few systems. Considering that virtually every animal on Earth evolved with and among the microbes in its environment, there is still immense potential for discovering fundamentally new mechanisms of interaction among the staggering diversity of animals and their microbial symbionts in nature. The ancient and exclusive association between marine lucinid clams and chemosynthetic symbiotic bacteria is ideal for investigating these interactions. Lucinidae is one of the most widespread and species-rich animal families in the oceans today, and has lived in symbiosis for more than 400 million years. The clam’s outstanding ability to select one specific symbiont from the trillions of bacteria in its environment challenges widely held assumptions about the function and specificity of the innate immune system. Symbiont-free juveniles can be raised in the lab, and experimentally infected, allowing unmatched insights into the early development of this symbiosis. Although the symbiont infection is specific to gill cells, symbiont-encoded proteins can be found in distant parts of the animal that are symbiont-free. I will combine cutting-edge molecular tools and experimental infection to better understand three key aspects of host-microbe interactions in these clams: 1) Acquisition and selection of microbes during animal development, 2) Maintenance along animal lifetimes through molecular communication and exchange, and 3) Emergence and perpetuation over evolution. I hypothesize that intracellular bacterial symbionts fundamentally alter host biology, and these effects are not limited to the location where symbionts are housed, but can affect distant organ systems. My overarching goal is to understand the molecular basis for these effects, and their evolutionary history.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "EVOLUCIN" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "EVOLUCIN" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ENUF (2019)

Evaluation of Novel Ultra-Fast selective III-V Epitaxy

Read More  

HydroLieve (2018)

A long-lasting non-migrating hydrogel for relieving chronic pain

Read More  

Aware (2019)

Aiding Antibiotic Development with Deep Analysis of Resistance Evolution

Read More