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AURORAX SIGNED

Advancing cancer detection through metabolism-based diagnostics

Total Cost €

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EC-Contrib. €

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Partnership

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 AURORAX project word cloud

Explore the words cloud of the AURORAX project. It provides you a very rough idea of what is the project "AURORAX" about.

recurrence    diagnostics    carcinoma    urine    quantification    blood    first    off    diagnosed    ups    liquid    regulatory    introduce    obtain    20    exceptional    niche    regular    market    recurrences    basis    solid    starting    urologists    validation    follow    monitoring    12    expressing    detect    risks    surgery    sensitivity    aur87    cancer    launch    enter    ing    rates    signature    trials    patients    outcomes    companies    renal    sales    letters    139    platform    risk    treatment    sweden    radiation    scalable    rcc    indications    multiple    survival    detected    clearance    pharmaceutical    generate    effectiveness    financially    former    business    independent    signed    terminal    competition    surveil    easily    frequency    stages    metabolism    oncologist    annual    receive    200b    elypta    improves    biopsy    letter    significantly    limited    demonstrated    perform    metastatic    small    once    disease    optimize    frequent    laboratories    stage    drop    trial    strategy    imaging    cell    ruo    algorithmic    aurorax    benefit    too    metabolite    clinical    patient   

Project "AURORAX" data sheet

The following table provides information about the project.

Coordinator
ELYPTA AB 

Organization address
address: REGERINGSGATAN 65, 3TR
city: STOCKHOLM
postcode: 111 56
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 3˙346˙674 €
 EC max contribution 2˙342˙671 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ELYPTA AB SE (STOCKHOLM) coordinator 2˙342˙671.00

Map

 Project objective

Former cancer patients receive regular follow-ups to detect recurrences at early stages and optimize treatment outcomes. The follow-up frequency is currently limited by costs and radiation risks of imaging approaches used to surveil for recurrences, resulting in recurrences being detected too late – often resulting in terminal disease. Of the 139.000 annual Renal Cell Carcinoma (RCC) patients, 20% are diagnosed with a metastatic recurrence within 5 years after surgery. Once metastatic, RCC survival rates drop to 12% over 5 years survival. Elypta, Sweden, has developed the first metabolism-based liquid biopsy to detect early-stage recurrences. The quantification of a metabolite signature in blood or urine and an algorithmic analysis allows for exceptional sensitivity, a low cost of the platform and significantly improves on imaging approaches in cost and risk, enabling frequent patient follow-up. Elypta’s technology has been demonstrated in small clinical trials and its cost effectiveness assessed by two independent companies. Elypta’s platform is easily scalable to other cancer indications and applications such as treatment monitoring, as demonstrated in multiple small trials. Starting in the niche RCC market with limited competition, Elypta now requires clinical evidence for a product launch within RCC. The business strategy focuses on distribution and sales through clinical laboratories, which will benefit financially off sales. During the AURORAX, Elypta will 1) perform a clinical validation trial (AUR87) to generate strong clinical evidence, 2) obtain regulatory clearance in the EU and the US and 3) introduce the product for research use only (RUO) and after clinical validation enter the RCC diagnostics market in EU. As users of the platform, oncologist and urologists have all signed letters of support. A pharmaceutical partner has also signed a letter of support, expressing their interest in RUO use of the platform, providing a solid basis in the emerging liquid biopsy market (€200B market).

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The information about "AURORAX" are provided by the European Opendata Portal: CORDIS opendata.

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