Opendata, web and dolomites


Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

Total Cost €


EC-Contrib. €






 SUPRAVACC project word cloud

Explore the words cloud of the SUPRAVACC project. It provides you a very rough idea of what is the project "SUPRAVACC" about.

vaccine    combine    small    antiviral    induction    protein    assembling    entities    lives    applicable    modular    shelf    mimetic    functionalisation    attach    diseases    paradigm    grafted    particles    molecule    employ    individually    synthesise    academic    carrier    supramolecular    handling    toolbox    strategies    nanoscaled    decorated    limited    countries    lack    laboratories    immunostimulants    composition    unmet    minimalistic    antitumour    pharmaceutical    building    potent    vaccines    immunisations    epitopes    conjugation    insights    multipotent    subunit    molecular    formulations    pathogen    suffer    disease    team    antigens    units    supravacc    construct    engineering    platform    synthetic    proteins    endogenous    carbohydrate    blocks    polymer    broadly    protection    cancer    glycan    pioneer    memory    conjugates    candidates    radically    industrial    facile    peptides    self    drive    vaccinations    appended    glycopeptide    precise    immunological    preparation    shift    pathogens    universal    compounds    onto    fundamental    antibacterial    stability    gained    designed    serve   

Project "SUPRAVACC" data sheet

The following table provides information about the project.


Organization address
address: SAARSTRASSE 21
city: MAINZ
postcode: 55122

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-04-01   to  2024-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The main and most important feature of vaccines is the induction of an immunological memory response, which is key to providing long-term protection against pathogens. The current strategies for potent antibacterial and antiviral vaccines employ conjugation of pathogen specific entities onto carrier proteins, and are limited to formulations that suffer from low stability and short shelf-lives, and are thus not viable in developing countries. Strategies for the development of new vaccinations against endogenous diseases like cancer further remain an unmet challenge, since current methodologies suffer from a lack of a modular and tailored vaccine-specific functionalisation. I therefore propose a radically new design approach in the development of fully synthetic molecular vaccines. My team will synthesise carbohydrate and glycopeptide appended epitopes that are grafted onto supramolecular building blocks. These units can be individually designed to attach disease specific antigens and immunostimulants. Due to their self-assembling properties into nanoscaled pathogen mimetic particles, they serve as a supramolecular subunit vaccine toolbox. By developing a universal supramolecular polymer platform, we will construct multipotent vaccines from glycan-decorated peptides, that combine the activity of protein conjugates with the facile handling, precise composition and increased stability of traditional small molecule pharmaceutical compounds. SUPRAVACC will pioneer the design of minimalistic and broadly applicable vaccines, and will evaluate the supramolecular engineering approach for immunisations against antibacterial diseases, as well as for applications as antitumour vaccine candidates. The fundamental insights gained will drive a paradigm shift in the design and preparation of vaccine candidates in academic and industrial research laboratories.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SUPRAVACC" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SUPRAVACC" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

InsideChromatin (2019)

Towards Realistic Modelling of Nucleosome Organization Inside Functional Chromatin Domains

Read More  

EVOMENS (2020)

The evolution of menstruation in primates

Read More  


The Mass Politics of Disintegration

Read More