Opendata, web and dolomites


Large-scale identification of secondary metabolites, metabolic pathways and their genes in the model tree poplar

Total Cost €


EC-Contrib. €






 POPMET project word cloud

Explore the words cloud of the POPMET project. It provides you a very rough idea of what is the project "POPMET" about.

structures    metabolomics    made    crispr    sequenced    alleles    genes    resolving    lay    experimental    re    poplars    combination    progress    editing    trees    gap    rare    metabolic    750    biosynthetic    hindering    species    combined    true    predict    steady    informatics    effort    functional    identification    complementary    biology    enzyme    time    sequence    discovery    molecular    assays    industrial    genetic    defective    innovative    living    producing    foundation    heterozygous    genome    deep    tool    structural    identities    obtaining    scarce    structure    biomass    gene    gwas    systematically    unknown    purify    lack    crossing    wood    population    snps    metabolite    characterization    conversions    shape    leaves    subsequently    metabolites    poplar    cas9    woody    encoding    difficult    model    secondary    impedes    natural    predicted    crop    data    cspp    underpinned    bark    content    lab    functions    enzymes    either    association    abundance   

Project "POPMET" data sheet

The following table provides information about the project.


Organization address
postcode: 9052

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 2˙499˙251 €
 EC max contribution 2˙499˙251 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-ADG
 Funding Scheme ERC-ADG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    VIB VZW BE (ZWIJNAARDE - GENT) coordinator 2˙499˙251.00


 Project objective

Poplar is an important woody biomass crop and at the same time the model of choice for molecular research in trees. Although there is steady progress in resolving the functions of unknown genes, the identities of most secondary metabolites in poplar remain unknown. The lack of metabolite identities in experimental systems is a true gap in information content, and impedes obtaining deep insight into the complex biology of living systems. The main reason is that metabolites are difficult to purify because of their low abundance, hindering their structural characterization and the discovery of their biosynthetic pathways. In this project, we will use CSPP, an innovative method recently developed in my lab, to systematically predict the structures of metabolites along with their biosynthetic pathways in poplar wood, bark and leaves. This CSPP method is based on a combination of metabolomics and informatics. In a next step, the CSPP tool will be combined with two complementary genetic approaches based on re-sequence data from 750 poplar trees to identify the genes encoding the enzymes in the predicted pathways. Genome Wide Association Studies (GWAS) will be made to identify SNPs in the genes involved in the metabolic conversions. Subsequently, rare defective alleles will be identified for these genes in the sequenced population. Genes identified by both approaches will then be further studied either by crossing natural poplars that are heterozygous for the defective alleles, or by CRISPR/Cas9-based gene editing in poplar. The functional studies will be further underpinned by enzyme assays. Given our scarce knowledge on the structure of most secondary metabolites and their metabolic pathways in poplar, this large-scale identification effort will lay the foundation for systems biology research in this species, and will shape opportunities to further develop poplar as an industrial wood-producing crop.


List of deliverables.
data management plan Open Research Data Pilot 2020-02-12 17:34:21

Take a look to the deliverables list in detail:  detailed list of POPMET deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "POPMET" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "POPMET" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

PSYDISC (2020)

Developing and Testing the Psychological Distance to Science Model

Read More  

ChaperoneRegulome (2020)

ChaperoneRegulome: Understanding cell-type-specificity of chaperone regulation

Read More  



Read More