Opendata, web and dolomites

LEECHSYMBIO SIGNED

The Mexican leech Haementeria officinalis and its nutritional symbiont as a model system for the study of strict blood-feeding animal-microbe symbioses and bacteriocyte development

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 LEECHSYMBIO project word cloud

Explore the words cloud of the LEECHSYMBIO project. It provides you a very rough idea of what is the project "LEECHSYMBIO" about.

molecular    genome    independent    stages    vitamin    symbionts    evolution    mexican    experiments    animals    providencia    probing    ensures    isotope    diet    metabolic    organs    metabolomics    lab    genomic    additional    officinalis    ideal    haementeria    biosynthesis    analysed    showed    evolutionary    colonization    leeches    genes    supplement    imaging    host    bacteriome    intracellular    sequenced    interactions    helobdella    strict    determinants    organ    feeding    habit    species    genomes    bioinformatics    insights    symbiont    reconstruct    microbe    siddallii    leech    determined    chemical    rely    efficient    blood    techniques    specialised    developmental    medically    identification    intricacies    researcher    acquisition    symbioses    environment    core    complementarity    symbiosis    truly    background    houses    model    unbalanced    robusta    postdoc    history    experimental    transfer    bacterial    sequence    deficiency    maintained    nutritional    confronted    microscopy   

Project "LEECHSYMBIO" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT WIEN 

Organization address
address: UNIVERSITATSRING 1
city: WIEN
postcode: 1010
website: www.univie.ac.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 186˙167 €
 EC max contribution 186˙167 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-15   to  2022-01-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT WIEN AT (WIEN) coordinator 186˙167.00

Map

 Project objective

Strict blood-feeding leeches are confronted with a strong B-vitamin deficiency and thus rely on bacterial symbionts to supplement their unbalanced diet. Recent evidence showed that the Mexican leech Haementeria officinalis houses in a distinct specialised organ intracellular Providencia siddallii symbionts, which have a highly reduced genome but maintained genes required for B vitamin biosynthesis. The aim of this proposal is to establish this leech as a model system for studying the intricacies of nutritional blood-feeding symbioses. The genomes of Providencia symbionts of 4 additional Haementeria species will be sequenced and analysed to identify core-metabolic pathways and to reconstruct the evolutionary history of this symbiosis. A draft genome sequence of the Mexican leech Ha. officinalis will be determined, providing unique insights into metabolic complementarity. Comparison with the available genome of the related non-blood-feeding leech Helobdella robusta will facilitate identification of genomic determinants of the acquisition/loss of the bacteriome and the blood feeding habit. Bacteriome development and colonization will be investigated using different developmental stages and advanced microscopy techniques. Host control and nutritional role of the symbiont will be studied using isotope probing experiments and state-of-the-art chemical imaging and metabolomics methods. This project will provide comprehensive insights into a nutritional symbiosis in medically relevant blood-feeding animals, including the evolution of specialised symbiosis organs and metabolic interactions between both partners. It will bring together a postdoc with a strong background in bioinformatics and bacterial symbionts with a host lab focused on experimental and molecular analysis of microbe-host interactions. This set-up ensures both an ideal environment for the postdoc on his way to an truly independent researcher, and an efficient two-way transfer of knowledge.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LEECHSYMBIO" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LEECHSYMBIO" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

STIMOS (2019)

Stimulation of Multiple Organoids Simultaneously

Read More  

VINCI (2020)

The Value of Information and Choice to Improve Control.

Read More  

MarshFlux (2020)

The effect of future global climate and land-use change on greenhouse gas fluxes and microbial processes in salt marshes

Read More