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TUBE SIGNED

Transport derived Ultrafines and the Brain Effects

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "TUBE" data sheet

The following table provides information about the project.

Coordinator
ITA-SUOMEN YLIOPISTO 

Organization address
address: YLIOPISTONRANTA 1 E
city: KUOPIO
postcode: 70211
website: www.uef.fi

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 5˙989˙370 €
 EC max contribution 5˙049˙876 € (84%)
 Programme 1. H2020-EU.3.4. (SOCIETAL CHALLENGES - Smart, Green And Integrated Transport)
 Code Call H2020-MG-2018-TwoStages
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2023-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ITA-SUOMEN YLIOPISTO FI (KUOPIO) coordinator 891˙170.00
2    UNIVERSITEIT UTRECHT NL (UTRECHT) participant 578˙856.00
3    Teknologian tutkimuskeskus VTT Oy FI (Espoo) participant 520˙086.00
4    INSTITUT FUR UMWELTMEDIZINISCHE FORSCHUNG AN DER HEINRICH-HEINE-UNIVERSITAT DUSSELDORF GMBH DE (DUESSELDORF) participant 403˙040.00
5    MIMETAS BV NL (Leiden) participant 400˙393.00
6    BIOTALENTUM TUDASFEJLESZTO KFT HU (GOEDOELLO) participant 361˙875.00
7    USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE CZ (PRAHA 4) participant 337˙772.00
8    TAMPEREEN KORKEAKOULUSAATIO SR FI (TAMPERE) participant 337˙087.00
9    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 294˙467.00
10    UMEA UNIVERSITET SE (UMEA) participant 262˙625.00
11    UNIVERSITY OF SOUTHAMPTON UK (SOUTHAMPTON) participant 232˙868.00
12    ILMATIETEEN LAITOS FI (HELSINKI) participant 220˙000.00
13    VSPARTICLE BV NL (DELFT) participant 110˙887.00
14    CENTRO PREMIO NOBEL MARIO MOLINA PARA ESTUDIOS ESTRATEGICOS SOBRE ENERGIA Y MEDIO AMBIENTE CHILE LIMITADA CL (SANTIAGO DE CHILE) participant 98˙750.00
15    SUN YAT-SEN UNIVERSITY CN (GUANGZHOU) participant 0.00

Map

 Project objective

The aim of the research is to study the effects of smallest traffic related ultrafine- or nanoparticles beyond the lung on brain health. Air pollutants have been shown to cause a vast amount of different adverse health effects. These effects include impairment of many respiratory (e.g. asthma, COPD) and cardiovascular (ischemic heart disease, infarction, stroke) diseases. However, in recent years, the evidence showing effects beyond the lungs and circulatory system are becoming more evident. Neurological diseases, namely Alzheimer´s disease (AD) has shown to be associated with living near traffic. However, reason for this has remained unresolved until today. This consortium aims on revealing the mechanisms and exposures both behind cardiorespiratory diseases and beyond the current knowledge in neurological diseases. This consortium includes experts in areas of aerosol technology, emission research, engine and fuel research, human clinical studies, epidemiology, emission inventories, inhalation toxicology, neurotoxicology and disease mechanism studies. This enables research of resolving the effects of nanoparticles from different traffic modes for both air quality and concomitant toxic effect of these air pollutants. In this study, we will investigate adverse effects of air pollutants using cell cultures, animal exposures and volunteered human exposures as well as the material from epidemiological cohort study. These are going to be compared according to inflammatory, cytotoxic and genotoxic changes and furthermore beyond the current state of the art to neurotoxic and brain health effects. With this approach, we are aiming in to a comprehensive understanding of the adverse effects of nanoparticles from traffic. In current situation only particles above 23nm are measured in regulations, traditional toxicological methods are used in risk assessment and emission inventories and regulations are largely based on old technology engines. Our project will change this.

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The information about "TUBE" are provided by the European Opendata Portal: CORDIS opendata.

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