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SpheriCal

Reference Certification and Commercialisation of “Universal” Mass Spectrometry Calibration Standards

Total Cost €

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EC-Contrib. €

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Partnership

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 SpheriCal project word cloud

Explore the words cloud of the SpheriCal project. It provides you a very rough idea of what is the project "SpheriCal" about.

synthetic    successful    reinforce    cover    peak    miss    calibrants    lack    certified    instrumentation    regular    organic    spectrometers    6month    biochemistry    infection    accurately    spectrometry    false    raw    benchmark    techniques    preliminary    bacteria    resolution    ms    additional    positives    reference    bacterial    exhibits    validation    drift    accurate    building    strict    standards    technique    ionization    analytes    microbiology    regulatory    consuming    clinical    prominence    limiting    confirm    critically    discovery    biomolecules    monitoring    calibration    runs    drug    biological    spherical    preparation    polymers    status    throughput    continuous    assignment    lucrative    molecules    poor    time    disadvantages    trials    crm    im    data    industries    mass    reg    material    components    fingerprint    overcome    insufficient    economic    misleading    clinically    attempting    cutting    shortcomings    environmental    experiments    feasibility    pf    techno    absolute    maldi    esi    efficiency    edge    analytical    electrospray    biomedical    markets    recorded    small    species    nature    diagnostics    medicine    commercialize    media   

Project "SpheriCal" data sheet

The following table provides information about the project.

Coordinator
POLYMER FACTORY SWEDEN AB 

Organization address
address: TEKNIKRINGEN 48 1 TR
city: STOCKHOLM
postcode: 114 28
website: www.polymerfactory.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website https://www.polymerfactory.com/horizon-2020
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2019-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    POLYMER FACTORY SWEDEN AB SE (STOCKHOLM) coordinator 50˙000.00

Map

 Project objective

Mass spectrometry (MS) is an established benchmark analytical technique to analyse biomolecules, organic molecules and synthetic polymers. MS techniques such as MALDI, IM-MS and ESI (electrospray ionization) are widely used in a range of fields such as biochemistry, clinical microbiology, medicine and drug discovery. Its prominence in these fields is due to the ability to accurately measure the absolute mass, and therefore species present, in complex analytes such as raw biological media, in high throughput experiments. For example, MALDI is used clinically to identify the nature of bacterial infection through the unique biological fingerprint of each bacteria type.

Critically, due to small and continuous changes in the various system components, data recorded exhibits a significant drift over time and between analysis runs, leading to peak miss-assignment and misleading data such as false positives. Therefore, mass spectrometers require regular calibration with a set of known standards in order to provide accurate and meaningful data. Without accurate calibration, MS instrumentation will not produce reliable data, limiting the advancement and efficiency of biomedical and clinical industries and environmental monitoring organizations. Existing calibrants have disadvantages such as time-consuming preparation, poor resolution, cover an insufficient mass range and lack Certified Reference Material (CRM) status.

To overcome these shortcomings of the existing calibrants, PF aim to commercialize a set of cutting-edge synthetic calibration standards called SpheriCal®. We are now attempting to reinforce SpheriCal® as a calibration system with CRM status – allowing access to additional lucrative markets such as clinical diagnostics and other markets with strict regulatory requirements.

Building upon successful development and validation through preliminary end-user trials, through this 6month Phase 1 project we aim to confirm the techno-economic feasibility of SpheriCal

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The information about "SPHERICAL" are provided by the European Opendata Portal: CORDIS opendata.

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