Explore the words cloud of the PAVE project. It provides you a very rough idea of what is the project "PAVE" about.
The following table provides information about the project.
|Coordinator Country||Netherlands [NL]|
|Total cost||4˙023˙616 €|
|EC max contribution||4˙023˙616 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2019-10-01 to 2023-09-30|
Take a look of project's partnership.
|1||PERCUROS BV||NL (LEIDEN)||coordinator||265˙619.00|
|2||ACADEMISCH ZIEKENHUIS LEIDEN||NL (LEIDEN)||participant||531˙239.00|
|3||MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV||DE (MUENCHEN)||participant||505˙576.00|
|4||THE UNIVERSITY OF BIRMINGHAM||UK (BIRMINGHAM)||participant||303˙172.00|
|5||DANMARKS TEKNISKE UNIVERSITET||DK (KGS LYNGBY)||participant||297˙522.00|
|6||POLYPURE AS||NO (OSLO)||participant||292˙342.00|
|7||INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE||FR (PARIS)||participant||274˙802.00|
|8||ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM||NL (ROTTERDAM)||participant||265˙619.00|
|9||GOOD BIOMARKER SCIENCES BV||NL (SASSENHEIM)||participant||265˙619.00|
|10||TECHNISCHE UNIVERSITEIT DELFT||NL (DELFT)||participant||265˙619.00|
|11||KLINIKUM DER UNIVERSITAET REGENSBURG||DE (REGENSBURG)||participant||252˙788.00|
|12||TECHNISCHE UNIVERSITAET MUENCHEN||DE (MUENCHEN)||participant||252˙788.00|
|13||UNIVERSITAT DE BARCELONA||ES (BARCELONA)||participant||250˙904.00|
A Nanovaccine Approach For The Treatment of Pancreatic Cancer By Multicomponent Immuno-Modulation: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths in men and women and still fatal in over 90% of patients. It is characterised by its extremely aggressive nature where it is also responsible for the highest mortality rate compared to other major cancers, resulting in excess of 250,000 deaths worldwide per annum. Current state-of-art therapies for advanced PDAC including chemo- and/or radiotherapy, despite extensive efforts, have met with only limited success. Surgery is only applicable for those with early stages of the disease, or to relieve symptoms, if the cancer is blocking the bile duct or the bowel. There are two major reasons for the resistance of PDAC to conventional therapy. Firstly, PDAC has a very defining hallmark, where an abundance of stromal content is present in the tumour microenvironment (TME) to form a physical and biochemical barrier. Secondly, during progression of the disease, the body's immune system is hijacked to support the proliferation of the cancer. New approaches, such as immunotherapy, are therefore needed where it has already shown promise in overcoming many aspects of this resistance. Immunotherapy has the potential to treat minimal residual disease after pancreatic resection (surgery) as well as for metastatic and non-resectable PDAC. Our objective for this project is to bring together a multidisciplinary and intersectoral group to develop novel vaccine approaches, including use of multiple immunomodulating components.
|year||authors and title||journal||last update|
Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17Î±-Methyltestosterone Delivery
published pages: 1181, ISSN: 1420-3049, DOI: 10.3390/molecules25051181
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The information about "PAVE" are provided by the European Opendata Portal: CORDIS opendata.
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