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AVANT SIGNED

Alternatives to Veterinary ANTimicrobials

Total Cost €

0

EC-Contrib. €

0

Partnership

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 AVANT project word cloud

Explore the words cloud of the AVANT project. It provides you a very rough idea of what is the project "AVANT" about.

risk    consumption    bacteriophages    threat    immuno    select    alternatives    alternative    feed    post    avant    zinc    formulation    mathematical    pork    public    consumers    action    farm    respiratory    demographics    prevention    advice    period    piglets    pig    restrictions    actor    limited    veterinarian    optimized    feeding    regulatory    weaning    antimicrobials    dosage    considerations    stabilizing    farmer    faecal    probiotic    enterotoxigenic    stimulating    coli    choices    survey    assessing    variety    welfare    portfolio    treatment    quick    transplantation    symbiotic    microbiota    clinical    veterinary    sows    health    market    humans    livestock    indication    efficacy    perception    gut    tested    pigs    infections    toxicity    transmission    injectable    trials    animal    antimicrobial    zoonotic    mode    bacterial    interventions    additive    options    projected    strategies    polymers    estimate    colistin    2030    entry    diarrhoea    sectorial    negative    resistance    economic    diseases    containing    medicinal    inter    data   

Project "AVANT" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 6˙537˙033 €
 EC max contribution 5˙999˙905 € (92%)
 Programme 1. H2020-EU.3.2.1.1. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
 Code Call H2020-SFS-2019-1
 Funding Scheme IA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 2˙254˙125.00
2    THE ROYAL VETERINARY COLLEGE UK (LONDON) participant 586˙756.00
3    SCHOTHORST FEED RESEARCH B.V. NL (LELYSTAD) participant 548˙121.00
4    UNIVERSIDAD COMPLUTENSE DE MADRID ES (MADRID) participant 515˙000.00
5    STICHTING WAGENINGEN RESEARCH NL (WAGENINGEN) participant 393˙931.00
6    RTDS - VEREIN ZUR FORDERUNG DER KOMMUNIKATION UND VERMITTLUNG VON FORSCHUNG, TECHNOLOGIE UND INNOVATION (RTDS VEREIN, ENGL. RTDS ASSOCIATION) AT (WIEN) participant 357˙791.00
7    LANDBRUG & FODEVARER F.M.B.A. DK (KOBENHAVN V) participant 282˙541.00
8    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 260˙420.00
9    KLIFOVET AG DE (MUNCHEN) participant 260˙181.00
10    COOPERL INNOVATION S.A.S FR (LAMBALLE) participant 240˙316.00
11    BIOMIN HOLDING GMBH AT (GETZERSDORF BEI TRAISMAUER) participant 123˙333.00
12    FEDERATION OF VETERINARIANS OF EUROPE AISBL BE (BRUXELLES) participant 96˙041.00
13    LABORATORIOS OVEJERO SA ES (LEON) participant 49˙364.00
14    EASY-AGRICARE AS DK (NYKOBING) participant 31˙981.00

Map

 Project objective

Antimicrobial resistance in livestock is a public health threat due to the risk of zoonotic transmission to humans and its negative consequences on animal health and welfare when diseases cannot be treated. AVANT is a multi-actor inter-sectorial project aimed at developing alternatives to antimicrobials for the management of bacterial infections in pigs, especially diarrhoea during the weaning period, as the major indication for antimicrobial use in livestock in Europe. Antimicrobial treatment options for pigs are increasingly limited because of planned restrictions in the use of colistin and zinc, two current choices for treatment of post-weaning diarrhoea. The AVANT portfolio comprises a variety of alternatives for treatment or prevention of diarrhoea and/or respiratory infections, namely (i) gut-stabilizing interventions based on a symbiotic (pre- and probiotic) product and faecal microbiota transplantation; (ii) novel veterinary medicinal products containing bacteriophages and polymers for targeted treatment of enterotoxigenic E.coli infections; (iii) immuno-stimulating injectable and feed additive products, and (iv) alternative feeding strategies targeting sows and piglets. During pre-clinical studies, efficacy, toxicity, and mode of action of these interventions is tested, and their dosage and formulation optimized. The results and a survey for veterinarian-, farmer- and consumers perception of antimicrobial alternatives, will be used together with legal and economic considerations to select three interventions for large-scale farm trials, assessing clinical efficacy and impact on antimicrobial use. All steps are supported by regulatory advice for quick market entry post-project. Generated and existing data on antimicrobial use, pig demographics and projected consumption of pork, will be used in mathematical modelling to estimate the reduction in antimicrobial use that could be achieved by 2030 if the AVANT alternatives were widely adopted in pig production.

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The information about "AVANT" are provided by the European Opendata Portal: CORDIS opendata.

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