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AVANT SIGNED

Alternatives to Veterinary ANTimicrobials

Total Cost €

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EC-Contrib. €

0

Partnership

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AVANT project word cloud

Explore the words cloud of the AVANT project. It provides you a very rough idea of what is the project "AVANT" about.

enterotoxigenic perception consumption formulation regulatory medicinal avant demographics 2030 period feed containing feeding gut antimicrobial health diarrhoea polymers stimulating select respiratory limited welfare prevention indication assessing veterinary advice market zoonotic post stabilizing humans pork estimate projected additive portfolio colistin trials pig risk bacterial entry interventions negative farm considerations clinical antimicrobials alternatives efficacy symbiotic strategies resistance livestock injectable dosage probiotic piglets diseases options survey sectorial transplantation tested choices bacteriophages microbiota alternative actor coli quick toxicity action treatment inter immuno optimized zinc public pigs threat animal economic consumers variety mode data sows farmer infections restrictions weaning veterinarian mathematical transmission faecal

Project "AVANT" data sheet

The following table provides information about the project.

Coordinator	KOBENHAVNS UNIVERSITET Organization address address: NORREGADE 10 city: KOBENHAVN postcode: 1165 website: www.ku.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Denmark [DK]
Total cost	6˙537˙033 €
EC max contribution	5˙999˙905 € (92%)
Programme	1. H2020-EU.3.2.1.1. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
Code Call	H2020-SFS-2019-1
Funding Scheme	IA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2024-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	KOBENHAVNS UNIVERSITET KOBENHAVNS UNIVERSITET Organization address address: NORREGADE 10 city: KOBENHAVN postcode: 1165 website: www.ku.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KOBENHAVN)	coordinator	2˙254˙125.00
2	THE ROYAL VETERINARY COLLEGE THE ROYAL VETERINARY COLLEGE Organization address address: ROYAL COLLEGE STREET city: LONDON postcode: NW1 OTU website: www.rvc.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	586˙756.00
3	SCHOTHORST FEED RESEARCH B.V. SCHOTHORST FEED RESEARCH B.V. Organization address address: MEERKOETENWEG 26 city: LELYSTAD postcode: 8200AM website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (LELYSTAD)	participant	548˙121.00
4	UNIVERSIDAD COMPLUTENSE DE MADRID UNIVERSIDAD COMPLUTENSE DE MADRID Organization address address: AVENIDA DE SENECA 2 city: MADRID postcode: 28040 website: http://www.ucm.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	515˙000.00
5	STICHTING WAGENINGEN RESEARCH STICHTING WAGENINGEN RESEARCH Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB website: http://www.wageningenur.nl/nl.htm contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (WAGENINGEN)	participant	393˙931.00
6	RTDS - VEREIN ZUR FORDERUNG DER KOMMUNIKATION UND VERMITTLUNG VON FORSCHUNG, TECHNOLOGIE UND INNOVATION (RTDS VEREIN, ENGL. RTDS ASSOCIATION) RTDS - VEREIN ZUR FORDERUNG DER KOMMUNIKATION UND VERMITTLUNG VON FORSCHUNG, TECHNOLOGIE UND INNOVATION (RTDS VEREIN, ENGL. RTDS ASSOCIATION) Organization address address: LERCHENGASSE 25/2-3 city: WIEN postcode: 1080 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	357˙791.00
7	LANDBRUG & FODEVARER F.M.B.A. LANDBRUG & FODEVARER F.M.B.A. Organization address address: AXELTORV 3 city: KOBENHAVN V postcode: 1609 website: www.lf.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KOBENHAVN V)	participant	282˙541.00
8	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	260˙420.00
9	KLIFOVET AG KLIFOVET AG Organization address address: GEYERSPERGERSTRASSE 27 city: MUNCHEN postcode: 80689 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	260˙181.00
10	COOPERL INNOVATION S.A.S COOPERL INNOVATION S.A.S Organization address address: 7 RUE DE LA JEANNAIE MAROUE ZONE INDUSTRIELLE city: LAMBALLE postcode: 22400 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LAMBALLE)	participant	240˙316.00
11	BIOMIN HOLDING GMBH BIOMIN HOLDING GMBH Organization address address: ERBER CAMPUS 1 city: GETZERSDORF BEI TRAISMAUER postcode: 3131 website: www.biomin.net contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GETZERSDORF BEI TRAISMAUER)	participant	123˙333.00
12	FEDERATION OF VETERINARIANS OF EUROPE AISBL FEDERATION OF VETERINARIANS OF EUROPE AISBL Organization address address: AVENUE DE TERVUEREN 12 city: BRUXELLES postcode: 1040 website: www.fve.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	96˙041.00
13	LABORATORIOS OVEJERO SA LABORATORIOS OVEJERO SA Organization address address: CTRA LEON VILECHA, 30 city: LEON postcode: 24192 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (LEON)	participant	49˙364.00
14	EASY-AGRICARE AS EASY-AGRICARE AS Organization address address: OSTERMOLLEVEJ 32 city: NYKOBING postcode: 7900 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (NYKOBING)	participant	31˙981.00

Map

Project objective

Antimicrobial resistance in livestock is a public health threat due to the risk of zoonotic transmission to humans and its negative consequences on animal health and welfare when diseases cannot be treated. AVANT is a multi-actor inter-sectorial project aimed at developing alternatives to antimicrobials for the management of bacterial infections in pigs, especially diarrhoea during the weaning period, as the major indication for antimicrobial use in livestock in Europe. Antimicrobial treatment options for pigs are increasingly limited because of planned restrictions in the use of colistin and zinc, two current choices for treatment of post-weaning diarrhoea. The AVANT portfolio comprises a variety of alternatives for treatment or prevention of diarrhoea and/or respiratory infections, namely (i) gut-stabilizing interventions based on a symbiotic (pre- and probiotic) product and faecal microbiota transplantation; (ii) novel veterinary medicinal products containing bacteriophages and polymers for targeted treatment of enterotoxigenic E.coli infections; (iii) immuno-stimulating injectable and feed additive products, and (iv) alternative feeding strategies targeting sows and piglets. During pre-clinical studies, efficacy, toxicity, and mode of action of these interventions is tested, and their dosage and formulation optimized. The results and a survey for veterinarian-, farmer- and consumers perception of antimicrobial alternatives, will be used together with legal and economic considerations to select three interventions for large-scale farm trials, assessing clinical efficacy and impact on antimicrobial use. All steps are supported by regulatory advice for quick market entry post-project. Generated and existing data on antimicrobial use, pig demographics and projected consumption of pork, will be used in mathematical modelling to estimate the reduction in antimicrobial use that could be achieved by 2030 if the AVANT alternatives were widely adopted in pig production.

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