Opendata, web and dolomites

BioSilica SIGNED

Materials synthesis in vivo – intracellular formation of nanostructured silica by microalgae

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 BioSilica project word cloud

Explore the words cloud of the BioSilica project. It provides you a very rough idea of what is the project "BioSilica" about.

engineer    undergoing    cellular    data    nevertheless    tools    takes    biomineralization    materials    biological    inaccessibility    area    cells    microalgae    hierarchical    situ    achievements    nanotechnology    surpass    magnificent    microscopy    diatoms    condensation    biocompatible    photonics    patterned    spectroscopy    genetically    mechanism    transient    array    outcomes    elucidate    silica    inside    nanoscale    environment    regulated    reaching    si    porous    combination    made    resolution    principles    functional    mineralization    prominent    stabilization    obstacle    custom    synthetic    feasible    image    suite    man    pharmaceuticals    phases    persistent    inspire    revolutionized    structural    silicification    wall    elucidating    intracellular    chemical    analyze    designed    electron    genetic    ray    concentration    environmentally    form    tough    diatom    cheap    marine    meso    cell    imaging    material    organisms    strategies    environmental    elusive    nano    hierarchically    nanometer    living    intricate    catalysis    place    investigations    surface   

Project "BioSilica" data sheet

The following table provides information about the project.

Coordinator
WEIZMANN INSTITUTE OF SCIENCE 

Organization address
address: HERZL STREET 234
city: REHOVOT
postcode: 7610001
website: www.weizmann.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-STG
 Funding Scheme ERC-STG
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) coordinator 1˙500˙000.00

Map

 Project objective

Organisms evolved the ability to form a magnificent array of functional materials, which surpass any man-made product. A prominent example is diatoms, marine microalgae that form an intricate cell-wall made of meso-porous silica. Diatom silica is a tough, hierarchically built, and biocompatible material that is environmentally friendly and cheap, making it an exciting target for nanotechnology. Nevertheless, the principles of this regulated formation mechanism remain elusive. A persistent obstacle for elucidating biomineralization processes is the inaccessibility of the cellular environment for structural and chemical investigations. Recently, far-reaching developments in electron microscopy have revolutionized our abilities to investigate chemical processes inside living organisms. It is now becoming feasible to image and analyze, with nanometer-scale resolution, an intracellular mineralization process. This proposal aims to elucidate the intracellular mechanism of silica formation by diatoms. We will study cells undergoing the silicification process in situ, using a suite of state-of-the-art electron and X-ray imaging and spectroscopy tools. The combination of structural and chemical data will enable us to elucidate: 1) The concentration and stabilization mechanism of transient Si phases in the cell. 2) The nanoscale environment in which silica condensation takes place. 3) Genetic and environmental strategies to engineer the silicification process for designed outcomes. Diatom silica is a promising material for applications such as photonics, pharmaceuticals, and catalysis, which require hierarchical, high-surface area, nano-materials. The achievements of this project will inspire synthetic methodologies to produce and design nano-patterned silica, and genetically-engineer the biological silicification process to produce custom-made materials.

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The information about "BIOSILICA" are provided by the European Opendata Portal: CORDIS opendata.

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