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MIX-UP SIGNED

MIXed plastics biodegradation and UPcycling using microbial communities

Total Cost €

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EC-Contrib. €

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Partnership

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 MIX-UP project word cloud

Explore the words cloud of the MIX-UP project. It provides you a very rough idea of what is the project "MIX-UP" about.

enzyme    circular    convert    vitro    recirculated    broad    valorise    combined    ubiquitous    plastics    cultures    plastic    pollution    alternative    transformations    vivo    biomass    protein    chain    recycling    routes    efficacy    degrading    stable    optimize    continuing    stability    capacities    six    vision    treatment    sustaining    adds    poorly    catalytic    sustainable    microbiomes    bio    subsequent    released    mixtures    building    material    selectively    degradation    recalcitrant    successive    efforts    demand    mechanical    least    feedstock    mix    ps    realises    added    salt    multidisciplinary    generating    spectrum    biodegradable    market    formulate    appropriate    binding    pp    enzymatic    remaining    chemicals    economy    enzymes    thereby    blocks    pur    temperature    physico    conversion    pla    industry    global    mechanically    fossil    pha    workflow    microbial    upcoming    pose    engineering    chemical    recycled    cocktails    considerable    environment    monomers    mixed    lack    polymers    quota    pet    streams    isolate    chinese    pe    self    waste   

Project "MIX-UP" data sheet

The following table provides information about the project.

Coordinator
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN 

Organization address
address: TEMPLERGRABEN 55
city: AACHEN
postcode: 52062
website: www.rwth-aachen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 7˙365˙335 €
 EC max contribution 5˙465˙335 € (74%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
 Code Call H2020-NMBP-BIO-CN-2019
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN DE (AACHEN) coordinator 1˙927˙796.00
2    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 780˙838.00
3    UNIVERSITAET GREIFSWALD DE (GREIFSWALD) participant 720˙638.00
4    BIOPLASTECH LTD IE (DUBLIN) participant 521˙882.00
5    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) participant 509˙955.00
6    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 417˙922.00
7    FORSCHUNGSZENTRUM JULICH GMBH DE (JULICH) participant 314˙426.00
8    AB Enzymes GmbH DE (Darmstadt) participant 158˙750.00
9    PGS PACIFIC GARBAGE SCREENING GMBH DE (AACHEN) participant 62˙625.00
10    SOPREMA FR (STRASBOURG) participant 50˙500.00

Map

 Project objective

The continuing demand for plastic products, the lack of appropriate recycling and the ubiquitous pollution of the environment with plastic waste pose a global challenge. An ambitious vision and considerable efforts are required to change the traditional value chain of plastics to a sustainable one, based on biodegradable plastics. In MIX-UP, plastic mixtures with five of the top six fossil-based recalcitrant plastics (PP, PE, PUR, PET, and PS), along with upcoming biodegradable plastics such as PLA and PHA, will be used as feedstock for microbial transformations, thereby generating a workflow that increases the recycling quota and adds value to poorly recycled plastics waste streams. Successive controlled enzymatic and microbial degradation of mechanically pre-treated plastics waste will be combined with subsequent microbial conversion to value-added chemicals and polymers by mixed cultures. We will optimize known plastics-degrading enzymes for high specific binding capacities, stability, and catalytic efficacy towards a broad spectrum of plastics polymers under high salt and temperature conditions by integrated protein engineering, and also isolate novel enzymes with activities on recalcitrant polymers. MIX-UP will also optimize the production of enzymes and formulate enzyme cocktails tailored to specific waste streams. Implementation of these enzymes, both in vitro and in vivo, enables stable self-sustaining microbiomes to convert the released plastic monomers selectively into at least six value-added products, key building blocks, and biomass. Any remaining material recalcitrant to enzymatic activity will be recirculated into the process after a physico-chemical treatment. The Chinese-European MIX-UP is a multidisciplinary and industry-driven consortium that addresses the market need for novel sustainable routes to valorise plastics waste streams. MIX-UP realises a circular (bio)-economy and could be a viable alternative for mechanical and chemical recycling.

 Publications

year authors and title journal last update
List of publications.
2020 Wing-Jin Li, Tanja Narancic, Shane T. Kenny, Paul-Joachim Niehoff, Kevin O’Connor, Lars M. Blank, Nick Wierckx
Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2020.00382
Frontiers in Microbiology 11 2020-04-15

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The information about "MIX-UP" are provided by the European Opendata Portal: CORDIS opendata.

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