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MIX-UP SIGNED

MIXed plastics biodegradation and UPcycling using microbial communities

Total Cost €

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EC-Contrib. €

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Partnership

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 MIX-UP project word cloud

Explore the words cloud of the MIX-UP project. It provides you a very rough idea of what is the project "MIX-UP" about.

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Project "MIX-UP" data sheet

The following table provides information about the project.

Coordinator
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN 

Organization address
address: TEMPLERGRABEN 55
city: AACHEN
postcode: 52062
website: www.rwth-aachen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 7˙365˙335 €
 EC max contribution 5˙465˙335 € (74%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
 Code Call H2020-NMBP-BIO-CN-2019
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN DE (AACHEN) coordinator 1˙927˙796.00
2    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 780˙838.00
3    UNIVERSITAET GREIFSWALD DE (GREIFSWALD) participant 720˙638.00
4    BIOPLASTECH LTD IE (DUBLIN) participant 521˙882.00
5    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) participant 509˙955.00
6    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 417˙922.00
7    FORSCHUNGSZENTRUM JULICH GMBH DE (JULICH) participant 314˙426.00
8    AB Enzymes GmbH DE (Darmstadt) participant 158˙750.00
9    PGS PACIFIC GARBAGE SCREENING GMBH DE (AACHEN) participant 62˙625.00
10    SOPREMA FR (STRASBOURG) participant 50˙500.00

Map

 Project objective

The continuing demand for plastic products, the lack of appropriate recycling and the ubiquitous pollution of the environment with plastic waste pose a global challenge. An ambitious vision and considerable efforts are required to change the traditional value chain of plastics to a sustainable one, based on biodegradable plastics. In MIX-UP, plastic mixtures with five of the top six fossil-based recalcitrant plastics (PP, PE, PUR, PET, and PS), along with upcoming biodegradable plastics such as PLA and PHA, will be used as feedstock for microbial transformations, thereby generating a workflow that increases the recycling quota and adds value to poorly recycled plastics waste streams. Successive controlled enzymatic and microbial degradation of mechanically pre-treated plastics waste will be combined with subsequent microbial conversion to value-added chemicals and polymers by mixed cultures. We will optimize known plastics-degrading enzymes for high specific binding capacities, stability, and catalytic efficacy towards a broad spectrum of plastics polymers under high salt and temperature conditions by integrated protein engineering, and also isolate novel enzymes with activities on recalcitrant polymers. MIX-UP will also optimize the production of enzymes and formulate enzyme cocktails tailored to specific waste streams. Implementation of these enzymes, both in vitro and in vivo, enables stable self-sustaining microbiomes to convert the released plastic monomers selectively into at least six value-added products, key building blocks, and biomass. Any remaining material recalcitrant to enzymatic activity will be recirculated into the process after a physico-chemical treatment. The Chinese-European MIX-UP is a multidisciplinary and industry-driven consortium that addresses the market need for novel sustainable routes to valorise plastics waste streams. MIX-UP realises a circular (bio)-economy and could be a viable alternative for mechanical and chemical recycling.

 Publications

year authors and title journal last update
List of publications.
2020 Wing-Jin Li, Tanja Narancic, Shane T. Kenny, Paul-Joachim Niehoff, Kevin O’Connor, Lars M. Blank, Nick Wierckx
Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2020.00382
Frontiers in Microbiology 11 2020-04-15

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The information about "MIX-UP" are provided by the European Opendata Portal: CORDIS opendata.

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