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MIX-UP SIGNED

MIXed plastics biodegradation and UPcycling using microbial communities

Total Cost €

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EC-Contrib. €

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Partnership

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MIX-UP project word cloud

Explore the words cloud of the MIX-UP project. It provides you a very rough idea of what is the project "MIX-UP" about.

mixtures binding routes successive realises self mechanical protein physico temperature enzymes efficacy enzyme polymers monomers conversion biodegradable pp ps thereby recycling streams released pur considerable microbiomes alternative recirculated vitro adds degradation subsequent material recalcitrant global lack engineering industry plastic six feedstock salt cultures capacities convert continuing workflow pla spectrum pe appropriate remaining circular environment stability economy blocks chain ubiquitous generating least pollution added valorise chemical degrading vivo chemicals waste demand pha pet efforts fossil sustainable poorly catalytic bio microbial combined isolate mixed quota multidisciplinary chinese broad biomass stable upcoming plastics transformations recycled cocktails mechanically sustaining formulate mix selectively treatment enzymatic pose optimize vision market building

Project "MIX-UP" data sheet

The following table provides information about the project.

Coordinator	RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN Organization address address: TEMPLERGRABEN 55 city: AACHEN postcode: 52062 website: www.rwth-aachen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	7˙365˙335 €
EC max contribution	5˙465˙335 € (74%)
Programme	1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
Code Call	H2020-NMBP-BIO-CN-2019
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2023-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN Organization address address: TEMPLERGRABEN 55 city: AACHEN postcode: 52062 website: www.rwth-aachen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (AACHEN)	coordinator	1˙927˙796.00
2	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	780˙838.00
3	UNIVERSITAET GREIFSWALD UNIVERSITAET GREIFSWALD Organization address address: DOMSTRASSE 11 city: GREIFSWALD postcode: 17489 website: www.uni-greifswald.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GREIFSWALD)	participant	720˙638.00
4	BIOPLASTECH LTD BIOPLASTECH LTD Organization address address: CASHEL ROAD UNIT 9 BLOCK C CASHEL BUSINESS CENTRE city: DUBLIN postcode: 12 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	521˙882.00
5	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Organization address address: BELFIELD city: DUBLIN postcode: 4 website: www.ucd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	509˙955.00
6	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	417˙922.00
7	FORSCHUNGSZENTRUM JULICH GMBH FORSCHUNGSZENTRUM JULICH GMBH Organization address address: WILHELM JOHNEN STRASSE city: JULICH postcode: 52428 website: www.fz-juelich.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (JULICH)	participant	314˙426.00
8	AB Enzymes GmbH AB Enzymes GmbH Organization address address: Feldbergstrasse 78 city: Darmstadt postcode: 64293 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Darmstadt)	participant	158˙750.00
9	PGS PACIFIC GARBAGE SCREENING GMBH PGS PACIFIC GARBAGE SCREENING GMBH Organization address address: STRUVERWEG 116 city: AACHEN postcode: 52070 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (AACHEN)	participant	62˙625.00
10	SOPREMA SOPREMA Organization address address: 14 RUE SAINT NAZAIRE city: STRASBOURG postcode: 67100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (STRASBOURG)	participant	50˙500.00

Map

Project objective

The continuing demand for plastic products, the lack of appropriate recycling and the ubiquitous pollution of the environment with plastic waste pose a global challenge. An ambitious vision and considerable efforts are required to change the traditional value chain of plastics to a sustainable one, based on biodegradable plastics. In MIX-UP, plastic mixtures with five of the top six fossil-based recalcitrant plastics (PP, PE, PUR, PET, and PS), along with upcoming biodegradable plastics such as PLA and PHA, will be used as feedstock for microbial transformations, thereby generating a workflow that increases the recycling quota and adds value to poorly recycled plastics waste streams. Successive controlled enzymatic and microbial degradation of mechanically pre-treated plastics waste will be combined with subsequent microbial conversion to value-added chemicals and polymers by mixed cultures. We will optimize known plastics-degrading enzymes for high specific binding capacities, stability, and catalytic efficacy towards a broad spectrum of plastics polymers under high salt and temperature conditions by integrated protein engineering, and also isolate novel enzymes with activities on recalcitrant polymers. MIX-UP will also optimize the production of enzymes and formulate enzyme cocktails tailored to specific waste streams. Implementation of these enzymes, both in vitro and in vivo, enables stable self-sustaining microbiomes to convert the released plastic monomers selectively into at least six value-added products, key building blocks, and biomass. Any remaining material recalcitrant to enzymatic activity will be recirculated into the process after a physico-chemical treatment. The Chinese-European MIX-UP is a multidisciplinary and industry-driven consortium that addresses the market need for novel sustainable routes to valorise plastics waste streams. MIX-UP realises a circular (bio)-economy and could be a viable alternative for mechanical and chemical recycling.

Publications

List of publications.
year	authors and title	journal	last update
2020	Wing-Jin Li, Tanja Narancic, Shane T. Kenny, Paul-Joachim Niehoff, Kevin Oâ€™Connor, Lars M. Blank, Nick Wierckx Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440 published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2020.00382	Frontiers in Microbiology 11	2020-04-15

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The information about "MIX-UP" are provided by the European Opendata Portal: CORDIS opendata.

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