MIX-UP SIGNED
MIXed plastics biodegradation and UPcycling using microbial communities
Total Cost €
0EC-Contrib. €
0Partnership
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0MIX-UP project word cloud
Explore the words cloud of the MIX-UP project. It provides you a very rough idea of what is the project "MIX-UP" about.
Project "MIX-UP" data sheet
The following table provides information about the project.
| Coordinator |
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Total cost | 7˙365˙335 € |
| EC max contribution | 5˙465˙335 € (74%) |
| Programme |
1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology) |
| Code Call | H2020-NMBP-BIO-CN-2019 |
| Funding Scheme | RIA |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-01-01 to 2023-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN | DE (AACHEN) | coordinator | 1˙927˙796.00 |
| 2 | AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS | ES (MADRID) | participant | 780˙838.00 |
| 3 | UNIVERSITAET GREIFSWALD | DE (GREIFSWALD) | participant | 720˙638.00 |
| 4 | BIOPLASTECH LTD | IE (DUBLIN) | participant | 521˙882.00 |
| 5 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN | IE (DUBLIN) | participant | 509˙955.00 |
| 6 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | participant | 417˙922.00 |
| 7 | FORSCHUNGSZENTRUM JULICH GMBH | DE (JULICH) | participant | 314˙426.00 |
| 8 | AB Enzymes GmbH | DE (Darmstadt) | participant | 158˙750.00 |
| 9 | PGS PACIFIC GARBAGE SCREENING GMBH | DE (AACHEN) | participant | 62˙625.00 |
| 10 | SOPREMA | FR (STRASBOURG) | participant | 50˙500.00 |
Map
Project objective
The continuing demand for plastic products, the lack of appropriate recycling and the ubiquitous pollution of the environment with plastic waste pose a global challenge. An ambitious vision and considerable efforts are required to change the traditional value chain of plastics to a sustainable one, based on biodegradable plastics. In MIX-UP, plastic mixtures with five of the top six fossil-based recalcitrant plastics (PP, PE, PUR, PET, and PS), along with upcoming biodegradable plastics such as PLA and PHA, will be used as feedstock for microbial transformations, thereby generating a workflow that increases the recycling quota and adds value to poorly recycled plastics waste streams. Successive controlled enzymatic and microbial degradation of mechanically pre-treated plastics waste will be combined with subsequent microbial conversion to value-added chemicals and polymers by mixed cultures. We will optimize known plastics-degrading enzymes for high specific binding capacities, stability, and catalytic efficacy towards a broad spectrum of plastics polymers under high salt and temperature conditions by integrated protein engineering, and also isolate novel enzymes with activities on recalcitrant polymers. MIX-UP will also optimize the production of enzymes and formulate enzyme cocktails tailored to specific waste streams. Implementation of these enzymes, both in vitro and in vivo, enables stable self-sustaining microbiomes to convert the released plastic monomers selectively into at least six value-added products, key building blocks, and biomass. Any remaining material recalcitrant to enzymatic activity will be recirculated into the process after a physico-chemical treatment. The Chinese-European MIX-UP is a multidisciplinary and industry-driven consortium that addresses the market need for novel sustainable routes to valorise plastics waste streams. MIX-UP realises a circular (bio)-economy and could be a viable alternative for mechanical and chemical recycling.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2020 |
Wing-Jin Li, Tanja Narancic, Shane T. Kenny, Paul-Joachim Niehoff, Kevin O’Connor, Lars M. Blank, Nick Wierckx Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440 published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2020.00382 |
Frontiers in Microbiology 11 | 2020-04-15 |
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