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A diagnostic device for personalized determination of vitamin B6 status and health

Total Cost €


EC-Contrib. €






 B6VitaStat project word cloud

Explore the words cloud of the B6VitaStat project. It provides you a very rough idea of what is the project "B6VitaStat" about.

medical    engineering    first    enzymes    diabetes    diverse    estimate    dependent    recognition    antibody    customized    stroke    active    reproducible    class    patients    kinds    mimics    entrepreneurship    enzyme    assay    levels    care    countries    combines    balanced    populations    diet    infrastructure    team    stringent    bound    blood    specialized    stronger    point    elderly    equipped    alcoholics    tests    deficiency    limited    continuous    reliability    nutrient    cheap    direct    tag    vitamin    constant    world    probe    performed    structure    suffer    erythrocytes    cofactor    expertise    sites    suited    status    desired    drawn    convenience    rates    risk    commercialization    monitoring    expensive    cardiovascular    speed    laboratories    b6vitastat    chemistry    hallmarked    incorporated    microarray    envisioned    binding    b6    doctor    termed    complementary    external    clinical    people    device    visualize    printed    disease    scope    basis    signal    cancer    array    detection    introduce    pronounced   

Project "B6VitaStat" data sheet

The following table provides information about the project.


Organization address
address: Arcisstrasse 21
postcode: 80333

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-05-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Vitamin B6 is an essential nutrient and part of a well-balanced diet. However, B6 deficiency is often observed in elderly people, diabetes patients and alcoholics and associated with higher rates of cardiovascular disease, stroke and cancer. All these risk populations need a stringent and continuous monitoring of B6 levels. At present B6 detection systems suffer from limited speed, scope, convenience and reliability. These tests require a medical doctor as well as external laboratories with expensive and specialized equipment for analysis increasing the overall costs. We here develop a customized assay for vitamin B6 detection with a desired application as reliable, cheap and easy-to-use point-of-care device. This assay system, termed B6VitaStat, is based on the direct monitoring of cofactor binding into diverse enzyme active sites which will be performed in erythrocytes drawn from blood. Key to B6VitaStat is a tailored probe which mimics the structure of the cofactor. This probe is equipped with a recognition tag allowing to visualize binding to B6-dependent enzymes. The less B6 is bound, the stronger the signal, the higher the overall deficiency. This principle will be incorporated in an easy-to-use device that is based on an antibody printed microarray hallmarked by its cheap and reproducible production. The robust array can be used world-wide including developing countries with less pronounced medical infrastructure. The B6VitaStat team combines complementary expertise including chemistry, engineering and entrepreneurship, which will provide a basis for the envisioned commercialization. Given that B6VitaStat will be the first device of this class we estimate a significant cost reduction compared to current clinical procedures. Overall, we aim to introduce a new device for constant monitoring B6 vitamin status in risk patients and provide a cheap, easy-to-use and reliable method suited for all kinds of applications including those in less-developed countries.

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The information about "B6VITASTAT" are provided by the European Opendata Portal: CORDIS opendata.

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