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B6VitaStat SIGNED

A diagnostic device for personalized determination of vitamin B6 status and health

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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0

 B6VitaStat project word cloud

Explore the words cloud of the B6VitaStat project. It provides you a very rough idea of what is the project "B6VitaStat" about.

suited    first    status    populations    blood    levels    risk    cardiovascular    limited    probe    scope    printed    estimate    doctor    medical    diabetes    desired    b6    continuous    bound    deficiency    laboratories    tag    class    visualize    commercialization    enzymes    detection    introduce    patients    cofactor    structure    world    engineering    speed    specialized    monitoring    care    diverse    disease    reliability    kinds    direct    stroke    device    microarray    suffer    recognition    sites    diet    rates    combines    cheap    hallmarked    countries    cancer    team    drawn    b6vitastat    antibody    vitamin    envisioned    expertise    erythrocytes    nutrient    balanced    enzyme    clinical    chemistry    alcoholics    customized    signal    basis    mimics    equipped    external    expensive    infrastructure    dependent    reproducible    binding    assay    stringent    tests    complementary    pronounced    constant    stronger    convenience    people    active    array    performed    entrepreneurship    point    termed    incorporated    elderly   

Project "B6VitaStat" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITAET MUENCHEN 

Organization address
address: Arcisstrasse 21
city: MUENCHEN
postcode: 80333
website: www.tu-muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) coordinator 150˙000.00

Map

 Project objective

Vitamin B6 is an essential nutrient and part of a well-balanced diet. However, B6 deficiency is often observed in elderly people, diabetes patients and alcoholics and associated with higher rates of cardiovascular disease, stroke and cancer. All these risk populations need a stringent and continuous monitoring of B6 levels. At present B6 detection systems suffer from limited speed, scope, convenience and reliability. These tests require a medical doctor as well as external laboratories with expensive and specialized equipment for analysis increasing the overall costs. We here develop a customized assay for vitamin B6 detection with a desired application as reliable, cheap and easy-to-use point-of-care device. This assay system, termed B6VitaStat, is based on the direct monitoring of cofactor binding into diverse enzyme active sites which will be performed in erythrocytes drawn from blood. Key to B6VitaStat is a tailored probe which mimics the structure of the cofactor. This probe is equipped with a recognition tag allowing to visualize binding to B6-dependent enzymes. The less B6 is bound, the stronger the signal, the higher the overall deficiency. This principle will be incorporated in an easy-to-use device that is based on an antibody printed microarray hallmarked by its cheap and reproducible production. The robust array can be used world-wide including developing countries with less pronounced medical infrastructure. The B6VitaStat team combines complementary expertise including chemistry, engineering and entrepreneurship, which will provide a basis for the envisioned commercialization. Given that B6VitaStat will be the first device of this class we estimate a significant cost reduction compared to current clinical procedures. Overall, we aim to introduce a new device for constant monitoring B6 vitamin status in risk patients and provide a cheap, easy-to-use and reliable method suited for all kinds of applications including those in less-developed countries.

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The information about "B6VITASTAT" are provided by the European Opendata Portal: CORDIS opendata.

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