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B6VitaStat SIGNED

A diagnostic device for personalized determination of vitamin B6 status and health

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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0

 B6VitaStat project word cloud

Explore the words cloud of the B6VitaStat project. It provides you a very rough idea of what is the project "B6VitaStat" about.

reliability    hallmarked    disease    nutrient    b6    world    external    cardiovascular    vitamin    probe    elderly    convenience    reproducible    recognition    device    constant    kinds    expertise    direct    signal    enzyme    blood    risk    cofactor    deficiency    specialized    diet    diabetes    array    dependent    first    desired    patients    stroke    b6vitastat    stronger    entrepreneurship    suited    structure    binding    sites    chemistry    combines    microarray    termed    pronounced    introduce    commercialization    balanced    continuous    medical    bound    tag    envisioned    monitoring    populations    active    expensive    alcoholics    basis    status    erythrocytes    drawn    clinical    mimics    class    tests    complementary    assay    rates    countries    printed    incorporated    infrastructure    team    antibody    cheap    customized    cancer    suffer    speed    limited    doctor    visualize    diverse    detection    performed    people    care    engineering    stringent    laboratories    scope    levels    enzymes    equipped    point    estimate   

Project "B6VitaStat" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITAET MUENCHEN 

Organization address
address: Arcisstrasse 21
city: MUENCHEN
postcode: 80333
website: www.tu-muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) coordinator 150˙000.00

Map

 Project objective

Vitamin B6 is an essential nutrient and part of a well-balanced diet. However, B6 deficiency is often observed in elderly people, diabetes patients and alcoholics and associated with higher rates of cardiovascular disease, stroke and cancer. All these risk populations need a stringent and continuous monitoring of B6 levels. At present B6 detection systems suffer from limited speed, scope, convenience and reliability. These tests require a medical doctor as well as external laboratories with expensive and specialized equipment for analysis increasing the overall costs. We here develop a customized assay for vitamin B6 detection with a desired application as reliable, cheap and easy-to-use point-of-care device. This assay system, termed B6VitaStat, is based on the direct monitoring of cofactor binding into diverse enzyme active sites which will be performed in erythrocytes drawn from blood. Key to B6VitaStat is a tailored probe which mimics the structure of the cofactor. This probe is equipped with a recognition tag allowing to visualize binding to B6-dependent enzymes. The less B6 is bound, the stronger the signal, the higher the overall deficiency. This principle will be incorporated in an easy-to-use device that is based on an antibody printed microarray hallmarked by its cheap and reproducible production. The robust array can be used world-wide including developing countries with less pronounced medical infrastructure. The B6VitaStat team combines complementary expertise including chemistry, engineering and entrepreneurship, which will provide a basis for the envisioned commercialization. Given that B6VitaStat will be the first device of this class we estimate a significant cost reduction compared to current clinical procedures. Overall, we aim to introduce a new device for constant monitoring B6 vitamin status in risk patients and provide a cheap, easy-to-use and reliable method suited for all kinds of applications including those in less-developed countries.

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The information about "B6VITASTAT" are provided by the European Opendata Portal: CORDIS opendata.

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