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B6VitaStat SIGNED

A diagnostic device for personalized determination of vitamin B6 status and health

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 B6VitaStat project word cloud

Explore the words cloud of the B6VitaStat project. It provides you a very rough idea of what is the project "B6VitaStat" about.

suffer    blood    first    recognition    cancer    device    bound    direct    commercialization    disease    cofactor    patients    binding    limited    enzyme    populations    enzymes    probe    sites    risk    stroke    engineering    kinds    hallmarked    basis    reliability    class    detection    active    rates    printed    estimate    pronounced    world    tag    constant    combines    b6vitastat    balanced    continuous    customized    performed    diverse    desired    microarray    reproducible    nutrient    infrastructure    speed    diabetes    stringent    entrepreneurship    termed    suited    team    erythrocytes    medical    b6    monitoring    mimics    structure    clinical    stronger    expensive    drawn    elderly    incorporated    chemistry    scope    introduce    convenience    tests    countries    dependent    status    diet    external    laboratories    alcoholics    specialized    array    envisioned    point    signal    people    vitamin    assay    deficiency    cheap    complementary    equipped    cardiovascular    care    doctor    visualize    levels    expertise    antibody   

Project "B6VitaStat" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITAET MUENCHEN 

Organization address
address: Arcisstrasse 21
city: MUENCHEN
postcode: 80333
website: www.tu-muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) coordinator 150˙000.00

Map

 Project objective

Vitamin B6 is an essential nutrient and part of a well-balanced diet. However, B6 deficiency is often observed in elderly people, diabetes patients and alcoholics and associated with higher rates of cardiovascular disease, stroke and cancer. All these risk populations need a stringent and continuous monitoring of B6 levels. At present B6 detection systems suffer from limited speed, scope, convenience and reliability. These tests require a medical doctor as well as external laboratories with expensive and specialized equipment for analysis increasing the overall costs. We here develop a customized assay for vitamin B6 detection with a desired application as reliable, cheap and easy-to-use point-of-care device. This assay system, termed B6VitaStat, is based on the direct monitoring of cofactor binding into diverse enzyme active sites which will be performed in erythrocytes drawn from blood. Key to B6VitaStat is a tailored probe which mimics the structure of the cofactor. This probe is equipped with a recognition tag allowing to visualize binding to B6-dependent enzymes. The less B6 is bound, the stronger the signal, the higher the overall deficiency. This principle will be incorporated in an easy-to-use device that is based on an antibody printed microarray hallmarked by its cheap and reproducible production. The robust array can be used world-wide including developing countries with less pronounced medical infrastructure. The B6VitaStat team combines complementary expertise including chemistry, engineering and entrepreneurship, which will provide a basis for the envisioned commercialization. Given that B6VitaStat will be the first device of this class we estimate a significant cost reduction compared to current clinical procedures. Overall, we aim to introduce a new device for constant monitoring B6 vitamin status in risk patients and provide a cheap, easy-to-use and reliable method suited for all kinds of applications including those in less-developed countries.

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The information about "B6VITASTAT" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2022-11-27 5:01:54) correctly updated