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B6VitaStat SIGNED

A diagnostic device for personalized determination of vitamin B6 status and health

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 B6VitaStat project word cloud

Explore the words cloud of the B6VitaStat project. It provides you a very rough idea of what is the project "B6VitaStat" about.

diabetes    tag    chemistry    reliability    diverse    enzyme    vitamin    expensive    balanced    drawn    risk    first    disease    patients    binding    b6    world    class    medical    suited    commercialization    recognition    device    alcoholics    constant    cardiovascular    engineering    hallmarked    assay    populations    laboratories    convenience    reproducible    external    blood    status    mimics    doctor    tests    performed    team    antibody    erythrocytes    b6vitastat    signal    infrastructure    cofactor    desired    continuous    incorporated    speed    specialized    probe    printed    suffer    cheap    point    expertise    combines    diet    basis    countries    nutrient    pronounced    stroke    entrepreneurship    complementary    envisioned    rates    stringent    cancer    sites    introduce    care    elderly    equipped    limited    termed    active    kinds    estimate    bound    people    clinical    structure    direct    microarray    stronger    levels    customized    enzymes    array    deficiency    detection    monitoring    scope    visualize    dependent   

Project "B6VitaStat" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITAET MUENCHEN 

Organization address
address: Arcisstrasse 21
city: MUENCHEN
postcode: 80333
website: www.tu-muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) coordinator 150˙000.00

Map

 Project objective

Vitamin B6 is an essential nutrient and part of a well-balanced diet. However, B6 deficiency is often observed in elderly people, diabetes patients and alcoholics and associated with higher rates of cardiovascular disease, stroke and cancer. All these risk populations need a stringent and continuous monitoring of B6 levels. At present B6 detection systems suffer from limited speed, scope, convenience and reliability. These tests require a medical doctor as well as external laboratories with expensive and specialized equipment for analysis increasing the overall costs. We here develop a customized assay for vitamin B6 detection with a desired application as reliable, cheap and easy-to-use point-of-care device. This assay system, termed B6VitaStat, is based on the direct monitoring of cofactor binding into diverse enzyme active sites which will be performed in erythrocytes drawn from blood. Key to B6VitaStat is a tailored probe which mimics the structure of the cofactor. This probe is equipped with a recognition tag allowing to visualize binding to B6-dependent enzymes. The less B6 is bound, the stronger the signal, the higher the overall deficiency. This principle will be incorporated in an easy-to-use device that is based on an antibody printed microarray hallmarked by its cheap and reproducible production. The robust array can be used world-wide including developing countries with less pronounced medical infrastructure. The B6VitaStat team combines complementary expertise including chemistry, engineering and entrepreneurship, which will provide a basis for the envisioned commercialization. Given that B6VitaStat will be the first device of this class we estimate a significant cost reduction compared to current clinical procedures. Overall, we aim to introduce a new device for constant monitoring B6 vitamin status in risk patients and provide a cheap, easy-to-use and reliable method suited for all kinds of applications including those in less-developed countries.

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The information about "B6VITASTAT" are provided by the European Opendata Portal: CORDIS opendata.

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