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AFFECT-EU SIGNED

DIGITAL, RISK-BASED SCREENING FOR ATRIAL FIBRILLATION IN THE EUROPEAN COMMUNITY

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "AFFECT-EU" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF 

Organization address
address: Martinistrasse 52
city: HAMBURG
postcode: 20251
website: www.uke.uni-hamburg.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 8˙182˙458 €
 EC max contribution 5˙947˙925 € (73%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF DE (HAMBURG) coordinator 1˙471˙735.00
2    REGION HOVEDSTADEN DK (HILLEROD) participant 846˙991.00
3    LINKOPINGS UNIVERSITET SE (LINKOPING) participant 821˙038.00
4    TERVEYDEN JA HYVINVOINNIN LAITOS FI (HELSINKI) participant 673˙853.00
5    SOCIETE EUROPEENNE DE CARDIOLOGIE FR (BIOT SOPHIA ANTIPOLIS) participant 459˙945.00
6    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 249˙563.00
7    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 229˙870.00
8    EDINBURGH NAPIER UNIVERSITY UK (EDINBURGH) participant 157˙437.00
9    HEALTH SERVICE EXECUTIVE HSE IE (NAAS) participant 126˙918.00
10    KOMPETENZNETZ VORHOFFLIMMERN E.V. DE (Muenster) participant 109˙497.00
11    FACULTY OF MEDICINE, UNIVERSITY OF BELGRADE RS (BELGRADE) participant 103˙375.00
12    FONDAZIONE NEUROMED IT (POZZILLI) participant 92˙500.00
13    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) participant 91˙282.00
14    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 90˙000.00
15    UNIVERSITAETSKLINIKUM AACHEN DE (AACHEN) participant 89˙320.00
16    UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA IT (MODENA) participant 89˙046.00
17    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 58˙763.00
18    UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET NO (TROMSO) participant 55˙000.00
19    UMEA UNIVERSITET SE (UMEA) participant 53˙250.00
20    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 35˙785.00
21    THE TRUSTEES OF BOSTON UNIVERSITY US (BOSTON MA) participant 25˙500.00
22    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) participant 17˙252.00
23    MCMASTER UNIVERSITY CA (HAMILTON) participant 0.00
24    PFIZER PHARMA GMBH DE (BERLIN) participant 0.00
25    ROCHE DIAGNOSTICS INTERNATIONAL AG CH (ROTKREUZ) participant 0.00
26    THE UNIVERSITY OF SYDNEY AU (SYDNEY) participant 0.00

Map

 Project objective

Atrial fibrillation (AF) is an increasingly common arrhythmia in the aging European population. Its prevalence will more than double by the year 2050 affecting 5% of EU women and men aged ≥65 years. AF carries a high risk of stroke, heart failure, and dementia, which result in a significant loss of quality-adjusted life years and high mortality. The EU guiding principles for active aging (no. 17468/12) recommend disease prevention to maximise healthy life, and early detection of AF is recommended by the European Society of Cardiology (ESC). Nonetheless, to date, a risked-based screening strategy is lacking. AFFECT-EU’s major goal is the development of a risk-based, accurate, and ready for implementation AF screening algorithm, using digital devices, for early AF detection in the community. For this objective we will (1) Develop a risk-based AF screening algorithm, by combining the available information from the largest outcome trials (Danish LOOP, STROKESTOP, SAFER) and multiple screening studies across Europe (Ntotal>100,000) including health modifiers and biomarkers; (2) Refine the stratification of high-risk populations in a personalised approach through exploration of distinct digital screening methods and multiple health determinants in deeply-phenotyped population cohorts; (3) Validate the AFFECT-EU risked-based screening recommendations in a meta-analysis of European and world-wide studies; (4) Demonstrate cost benefits and acceptability of AF screening across different European healthcare systems; (5) Identify the AF screening potential to be taken up by differing healthcare systems; (6) Foster the dissemination of results and adoption of the risked-based AF screening algorithm in the ESC (an AFFECT-EU partner) guidelines. AFFECT-EU will develop the first targeted, risk-based AF screening algorithm, and thus contribute to the reduction of AF-related health inequities, morbidity and mortality in Europe.

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The information about "AFFECT-EU" are provided by the European Opendata Portal: CORDIS opendata.

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