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RISCC SIGNED

RISK-BASED SCREENING FOR CERVICAL CANCER

Total Cost €

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EC-Contrib. €

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Partnership

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Project "RISCC" data sheet

The following table provides information about the project.

Coordinator
STICHTING VUMC 

Organization address
address: DE BOELELAAN 1117
city: AMSTERDAM
postcode: 1081 HV
website: www.vumc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 5˙792˙355 €
 EC max contribution 5˙792˙355 € (100%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VUMC NL (AMSTERDAM) coordinator 1˙584˙871.00
2    PIRKANMAA HOSPITAL DISTRICT FI (TAMPERE) participant 1˙191˙708.00
3    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 855˙480.00
4    SCIENSANO BE (ELSENE) participant 662˙958.00
5    INSTITUT CATALA D'ONCOLOGIA ES (L'HOSPITALET DEL LLOBREGAT) participant 378˙125.00
6    SELF-SCREEN BV NL (AMSTERDAM) participant 300˙000.00
7    AZIENDA OSPEDALIERA CITTA DELLA SALUTE E DELLA SCIENZA DI TORINO IT (TORINO) participant 256˙250.00
8    UNIVERZA V LJUBLJANI SI (LJUBLJANA) participant 250˙461.00
9    REGION STOCKHOLM SE (STOCKHOLM) participant 200˙000.00
10    EUROPEAN SOCIETY OF GYNAECOLOGICAL CH (GENEVA) participant 112˙500.00
11    CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER FR (LYON CEDEX 08) participant 0.00

Map

 Project objective

Screening for cervical cancer is a globally recommended public health policy. Many risk factors are known, but so far only “one-size-fits-all” screening programs have been implemented, providing suboptimal protection for women at high risk, suboptimal allocation of resources and substantial screening-related harms. Development of risk-stratified screening is a priority, because cervical cancer is on the rise in many countries, the uptake of screening remains moderate in subpopulations at high risk, and costs related to screening are high. RISCC will develop risk-based screening based on screening history, HPV vaccination status and other relevant risk factors. Risk profiles based on screening history will be developed using joint data from several large European randomized HPV screening trials with long-term follow-up, HPV self-sampling trials, and registries of both cytology- and HPV-based screening programs. Risk profiles based on vaccination status will be developed for cohorts with varying screening and vaccination coverage using data from a community randomized vaccination trial, linked vaccination/screening/cancer registries, and a cohort of women vaccinated at screening age. Risk-based screening algorithms will be evaluated with respect to effectiveness, harms and costs by predictive and health-economic modelling. Finally, open source e-health and m-health applications using the risk-based screening algorithms will be developed to support implementation into real-life programs. The use of risk-based screening and a digital platform for screening invitations will be evaluated in an implementation trial within the Swedish organized screening program. The RISCC risk-based approach to cervical screening is directly related to the work program as it is based on a wealth of data sources on different, important risk factors for cervical cancer, builds on open science enabling citizens, and could thus constitute a role model for personalized screening.

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The information about "RISCC" are provided by the European Opendata Portal: CORDIS opendata.

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