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EXIMIOUS SIGNED

Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome

Total Cost €

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EC-Contrib. €

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Partnership

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 EXIMIOUS project word cloud

Explore the words cloud of the EXIMIOUS project. It provides you a very rough idea of what is the project "EXIMIOUS" about.

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Project "EXIMIOUS" data sheet

The following table provides information about the project.

Coordinator
KATHOLIEKE UNIVERSITEIT LEUVEN 

Organization address
address: OUDE MARKT 13
city: LEUVEN
postcode: 3000
website: www.kuleuven.be

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 10˙878˙331 €
 EC max contribution 10˙878˙331 € (100%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2019-Single-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) coordinator 4˙130˙715.00
2    FOLKEHELSEINSTITUTTET NO (OSLO) participant 1˙336˙685.00
3    BELGIAN CENTER FOR OCCUPATIONAL HYGIENE BE (GENT) participant 911˙271.00
4    "UNIVERSITATEA DE MEDICINA, FARMACIE, STIINTE SI TEHNOLOGIE ""GEORGE EMIL PALADE"" DIN TARGU MURES" RO (TARGU MURES) participant 771˙437.00
5    DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO DK (KOBENHAVN) participant 664˙875.00
6    UNIVERSITEIT HASSELT BE (HASSELT) participant 600˙725.00
7    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 549˙500.00
8    INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM BE (LEUVEN) participant 461˙025.00
9    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) participant 395˙500.00
10    THE BABRAHAM INSTITUTE UK (CAMBRIDGE) participant 256˙250.00
11    ACCELOPMENT AG CH (ZUERICH) participant 221˙890.00
12    BIOGENITY ApS DK (AALBORG) participant 180˙850.00
13    REGION HOVEDSTADEN DK (HILLEROD) participant 172˙000.00
14    THE QUEEN'S UNIVERSITY OF BELFAST UK (BELFAST) participant 158˙457.00
15    AARHUS UNIVERSITET DK (AARHUS C) participant 67˙150.00

Map

 Project objective

Immune-mediated, non-communicable diseases, such as autoimmune diseases, allergic diseases and asthma, are chronic disorders in which the interaction between exposome and immune system plays a pivotal role. As prevalence and societal costs of these diseases are rising in the EU, a holistic approach is needed. The EXIMIOUS consortium—gathering high-level experts in immunology, toxicology, clinical medicine, environmental hygiene, epidemiology, bioinformatics and sensor development—will bring about a new way of assessing the human exposome by linking innovative ways of characterizing and quantifying multiple and combined environmental exposures (exposomics) with high-dimensional immunophenotyping and -profiling platforms to map the (early) immune effects induced by these exposures (immunomics). In several cohorts—covering the entire lifespan, including prenatal life—we will extensively map exposome, immune system (immunome), other omics and clinical and socio-economic data, using two main methodologies—one starting from the exposome, the other starting from health effects—that ‘meet in the middle’. Novel bioinformatics tools, based on systems immunology and machine learning, will be used to integrate and analyse these huge datasets and to construct ‘immune fingerprints’ that reflect a person’s lifetime exposome and identify ‘immune fingerprints’ that are early signs of poor health and predictors of disease at the individual level. We will build a multifaceted toolbox for researchers, policy makers, clinicians and the general public containing the exposome/immunome tools developed during the project to help assess the impact of the exposome on the immune system at the level of individuals and populations. This will allow policy makers to grasp the components of the exposome that needs to be prioritized to be able to design targeted preventive policies to reduce healthcare and socioeconomic costs, leading to greater wellbeing for the EU population. EXIMIOUS will work together with the other projects (EXPANSE, HEAP, ATHLETE, EQUAL-LIFE, LONGITOOLS, EPHOR, REMEDIA and HEDIMED) funded within the Human Exposome programme call H2020-SC1-BHC-2018-2020, in order to achieve collaboration and synergy.

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The information about "EXIMIOUS" are provided by the European Opendata Portal: CORDIS opendata.

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