Explore the words cloud of the EDUC8 project. It provides you a very rough idea of what is the project "EDUC8" about.
The following table provides information about the project.
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
|Coordinator Country||France [FR]|
|Total cost||2˙100˙708 €|
|EC max contribution||2˙100˙708 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2020-04-01 to 2024-03-31|
Take a look of project's partnership.
|1||INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE||FR (PARIS)||coordinator||274˙802.00|
|2||COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES||FR (PARIS 15)||participant||274˙802.00|
|4||Stichting Sanquin Bloedvoorziening||NL (Amsterdam)||participant||265˙619.00|
|5||UNIVERSITA DEGLI STUDI DI MILANO||IT (MILANO)||participant||261˙499.00|
|6||JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN||DE (FRANKFURT AM MAIN)||participant||252˙788.00|
|7||TOPAS THERAPEUTICS GMBH||DE (HAMBURG)||participant||252˙788.00|
|8||UNIVERSITAETSKLINIKUM BONN||DE (BONN)||participant||252˙788.00|
The development of anti-drug antibodies is the major complication of treatment with biotherapeutics. This is particularly true of patients with haemophilia A (HA) who develop neutralizing antibodies to therapeutic factor VIII (FVIII) following replacement therapy with exogenous pro-coagulant FVIII. The onset of neutralizing antibodies to FVIII, referred to as FVIII inhibitors, represents a major societal concern owing to the enormous cost associated to the clinical management of inhibitor-positive patients, that exceeds 200,000€/patient/year. The EDUC8 program is a multidisciplinary training program with exposure of the enrolled ESRs to a core common educational package and development of individual PhD research projects dedicated to decreasing the societal burden associated with the development of anti-FVIII antibodies in Europe. The core educational program includes exposure to basic science in the fields of immunology and hemostasis, to the most advanced “omic” technologies in order to anticipate tomorrow’s scientific discoveries, and to the importance of ethical considerations and public awareness in today’s research. A key component of the training program is provided by immersion of the ESRs in a clinical center for HA, which will provide them with a unique experience and foster the conception of novel and realistic therapeutic approaches. The ESRs will exploit the accumulated theoretic and practical experience in an entrepreneurship training on key strategic, technical, financial and human resource issues required for the creation of startups. In a tribute to the concept of the fully developed mind coined by the French philosopher Michel de Montaigne on education, our ambition is to form a novel generation of scientists with deep scientific knowledge, multicultural exposure, imagination, pragmatism and understanding of both the academic and private sectors. This will foster translational research in European on the immunogenicity of therapeutic proteins.
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The information about "EDUC8" are provided by the European Opendata Portal: CORDIS opendata.