Opendata, web and dolomites

HaloCat SIGNED

Elemental Halogen-Free Reversible Construction and Deconstruction of 1,2-Dihalides via Shuttle Catalysis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 HaloCat project word cloud

Explore the words cloud of the HaloCat project. It provides you a very rough idea of what is the project "HaloCat" about.

excellent    compounds    expertise    fellowship    building    me    indispensable    besides    tackle    blocks    handling    toxic    materials    agrochemicals    realize    cl2    exceedingly    br2    rare    enantioselective    morandi    transfers    bromofluorination    excellence    mild    zurich    strategy    pharmaceuticals    daily    corrosive    halogenated    career    significantly    prof    containing    correcting    play    life    versatile    halogenating    asymmetric    demonstrating    caused    chemicals    risks    scientific    reversible    hazardous    alkynes    last    releasing    dihalogenation    enabled    helping    competences    first    eth    shuttle    reagents    reversibly    harsh    construct    deconstruct    molecules    brf    serve    unprecedented    alkenes    launch    combined    proposes    dihalides    dramatically    unrivaled    environment    practical    independent    suffer    multi    protocols    industry    interconversion    moiety    self    mechanism    devoted    formal    sustainable    catalysis    world    transfer    reaction    unmet    chemical    combination    bromofluorine    preliminary    feasibility    safety   

Project "HaloCat" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 203˙149 €
 EC max contribution 203˙149 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 203˙149.00

Map

 Project objective

Multi-halogenated compounds play a significant role in our daily life, as they are not only widely used as materials, pharmaceuticals, and agrochemicals but also serve as practical and indispensable building blocks in the chemical industry. However, most of the existing halogenating protocols suffer from safety risks and harsh reaction conditions caused by toxic and corrosive halogenating reagents (Cl2, Br2). Moreover, the enantioselective 1,2-dihalogenation of alkenes remains an unmet challenge. Besides, practical approaches to the versatile 1,2-bromofluorine-containing building blocks are exceedingly rare. Recently, the shuttle catalysis strategy, which reversibly transfers a chemical moiety between two molecules to construct and deconstruct compounds without handling hazardous reagents, is emerging as a potential strategy to tackle these long-standing challenges. This proposal aims to achieve the shuttle catalysis enabled reversible interconversion of 1,2-dihalides and alkenes/alkynes without using or releasing hazardous chemicals (e.g., Br2, Cl2, and BrF) under mild conditions. The first part is devoted to developing the reversible interconversion between 1,2-dihalides and alkenes. The second part aims to realize the enantioselective Br2 transfer between 1,2-dihalides and alkenes. The last part proposes to develop the unprecedented formal transfer 1,2-bromofluorination of alkenes via a unique self-correcting mechanism. The world-leading research environment of ETH Zurich combined with Prof. Morandi’s unrivaled scientific expertise on shuttle catalysis and my excellent knowledge of asymmetric catalysis offer the best combination to achieve the proposed research. This fellowship will dramatically improve my knowledge and competences, helping me launch my independent career. With promising preliminary results demonstrating the project’s feasibility, the proposed work will significantly contribute to the research excellence and sustainable development of the EU.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "HALOCAT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "HALOCAT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

Widow Spider Mating (2020)

Immature mating as a novel tactic of an invasive widow spider

Read More  

TARGET SLEEP (2020)

Boosting motor learning through sleep and targeted memory reactivation in ageing and Parkinson’s disease

Read More  

MY MITOCOMPLEX (2021)

Functional relevance of mitochondrial supercomplex assembly in myeloid cells

Read More