Opendata, web and dolomites

DNAGAM SIGNED

DNA-guided self-organized active materials

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DNAGAM project word cloud

Explore the words cloud of the DNAGAM project. It provides you a very rough idea of what is the project "DNAGAM" about.

cross    synthetic    exerting    shapeless    molecular    preparation    proteins    environments    travelling    programmable    network    inspired    clusters    guiding    diverse    active    biocompatible    dna    made    soft    methodology    group    material    shapes    autonomy    morphogenetic    man    predictably    manner    organization    microtubules    fronts    multiscale    programming    spatiotemporal    stark    ordered    macroscale    modular    action    conceptually    networks    waves    organism    natural    diffusion    structuring    integration    self    accomplished    embryo    first    autonomous    fabricated    stable    pioneered    cells    biomolecules    gels    kinesin    biological    single    motor    stranded    elusive    mechanical    indispensable    dependent    linking    physicochemical    concentrations    transformations    precision    starting    multistep    apart    later    generates    contrast    patterned    morphogenesis    act    shape    living    force    collective    host    linker    patterns    robotics    chemical    unknown    levels    exert    instruct    precise    morphogen    nanoscale    latter    combined    morphogens    entire    morphological    patterning    kinesins    equilibrium   

Project "DNAGAM" data sheet

The following table provides information about the project.

Coordinator
SORBONNE UNIVERSITE 

Organization address
address: 21 RUE DE L'ECOLE DE MEDECINE
city: PARIS
postcode: 75006
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2020
 Duration (year-month-day) from 2020-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SORBONNE UNIVERSITE FR (PARIS) coordinator 196˙707.00

Map

 Project objective

Programming the autonomous and multiscale structuring of shapeless synthetic soft matter is unknown and conceptually challenging. In stark contrast, a living embryo is highly ordered at all levels – from cells to the entire organism. The ordering is a multistep process, starting from the patterning of biomolecules (morphogens) which later instruct autonomous shape transformations (morphogenesis). Inspired by these natural physicochemical processes, we aim at the preparation of a first-ever synthetic biocompatible material which can be self-organized in a programmable and autonomous manner. The programming will be achieved by an out-of-equilibrium DNA-based chemical network which predictably generates single-stranded DNA morphogens. Combined with diffusion, the concentrations of the morphogen can be patterned with a unique spatiotemporal precision, including travelling waves and stable fronts, which were pioneered by the host group. The autonomy of morphological structuring will be accomplished by linking the mechanical activity of active gels, composed of DNA-kinesins and microtubules, to the presence of the DNA morphogen. Latter will act as a cross-linker creating the clusters of kinesins and thus guiding the self-organization of the soft material by the collective action of nanoscale kinesin motor proteins which exert force on microtubules. Apart from the preparation of a first biocompatible man-made morphogenetic material, we will learn how the self-organization of active gels is dependent on morphogens’ patterns. This knowledge is indispensable for the advanced programming of the precise macroscale shapes at the molecular level of chemical networks, which are diverse and modular. With further developments, our methodology could lead to so far elusive self-fabricated, force-exerting synthetic soft matter with the potential of integration in soft robotics and biological environments.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DNAGAM" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DNAGAM" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

CORRELATION (2020)

Characterization and prediction of service-level traffic for future sliced mobile network

Read More  

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More  

CoCoNat (2019)

Coordination in constrained and natural distributed systems

Read More