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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €

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EC-Contrib. €

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Partnership

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 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

engineering    regulating    genomics    differential    host    techniques    vistas    complementing    goals    forms    hook    follow    embryonic    synergistically    plants    training    soil    shown    biology    grant    germination    gained    wall    public    protects    lyon    ambition    researcher    survival    decipher    slu    yuan    replication    seedling    ens    interplay    personalized    damage    hormonal    achievement    critical    skills    experimental    upsc    cellular    folding    engagement    writing    plan    microscopy    young    cell    cytometry    ghent    apical    belgium    mentoring    environments    simultaneously    hypocotyl    dr    edge    dna    biochemistry    successful    leader    force    student    biomechanics    subsequent    shoot    outstanding    expertise    poorly    endoreduplication    mechanisms    ma    enclosed    fellowship    lab    opening    sweden    signals    phd    receive    flow    immunocytochemistry    career    seedlings    cutting    elucidation    tissue    division    passes    hypothesized    vib    plant    organisms    elongation    theoretical    stem    cells    plays    mechanics    atomic    meristem    secondments    ume    model    communication    aring    msca    deciphered    scientist    france    walls    rigid    developmental   

Project "MendoFold" data sheet

The following table provides information about the project.

Coordinator		 SVERIGES LANTBRUKSUNIVERSITET 

Organization address
address: ALMAS ALLE 8
city: UPPSALA
postcode: 750 07
website: http://www.slu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SVERIGES LANTBRUKSUNIVERSITET SE (UPPSALA) coordinator 203˙852.00

Map

 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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