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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €


EC-Contrib. €






 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

gained    engagement    cell    elucidation    mentoring    secondments    vib    differential    yuan    meristem    genomics    flow    deciphered    edge    opening    shown    cutting    replication    lab    hypothesized    seedlings    experimental    shoot    expertise    young    decipher    wall    signals    complementing    protects    career    biology    walls    environments    enclosed    force    outstanding    researcher    rigid    organisms    grant    synergistically    student    damage    public    writing    ghent    germination    embryonic    endoreduplication    immunocytochemistry    dr    successful    communication    hormonal    france    scientist    plan    dna    plant    microscopy    hypocotyl    belgium    skills    biomechanics    aring    goals    simultaneously    sweden    mechanics    theoretical    soil    leader    personalized    cytometry    division    phd    model    fellowship    achievement    passes    ambition    forms    stem    developmental    subsequent    plants    ume    hook    critical    training    techniques    cellular    cells    host    slu    vistas    poorly    mechanisms    seedling    elongation    ens    upsc    folding    tissue    follow    lyon    ma    survival    engineering    apical    msca    biochemistry    receive    atomic    interplay    plays    regulating   

Project "MendoFold" data sheet

The following table provides information about the project.


Organization address
address: ALMAS ALLE 8
postcode: 750 07

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2022-08-15 13:20:46) correctly updated