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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €

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EC-Contrib. €

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Partnership

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 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

personalized    elucidation    vistas    slu    cell    ume    belgium    interplay    skills    cellular    elongation    researcher    walls    aring    mentoring    follow    plants    developmental    achievement    plays    embryonic    opening    plant    ma    training    environments    endoreduplication    biomechanics    plan    protects    biochemistry    student    secondments    yuan    msca    decipher    outstanding    goals    force    engagement    forms    regulating    damage    wall    ens    organisms    seedlings    enclosed    hypothesized    signals    atomic    mechanics    simultaneously    young    dr    passes    ghent    expertise    public    host    hook    france    survival    successful    hypocotyl    apical    shoot    shown    grant    edge    ambition    immunocytochemistry    deciphered    stem    folding    gained    replication    career    germination    techniques    experimental    dna    cutting    tissue    engineering    flow    lab    cells    biology    scientist    communication    differential    leader    division    critical    genomics    synergistically    writing    theoretical    fellowship    hormonal    phd    cytometry    microscopy    poorly    sweden    vib    meristem    subsequent    receive    soil    model    complementing    rigid    mechanisms    lyon    seedling    upsc   

Project "MendoFold" data sheet

The following table provides information about the project.

Coordinator
SVERIGES LANTBRUKSUNIVERSITET 

Organization address
address: ALMAS ALLE 8
city: UPPSALA
postcode: 750 07
website: http://www.slu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SVERIGES LANTBRUKSUNIVERSITET SE (UPPSALA) coordinator 203˙852.00

Map

 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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