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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €

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EC-Contrib. €

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Partnership

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 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

synergistically    immunocytochemistry    passes    division    cutting    phd    expertise    grant    embryonic    atomic    soil    public    goals    biomechanics    survival    cell    enclosed    student    dna    france    communication    forms    walls    complementing    skills    host    plan    training    shoot    ume    seedling    microscopy    engagement    engineering    lyon    protects    germination    ens    differential    meristem    career    opening    techniques    interplay    simultaneously    upsc    hypocotyl    model    dr    seedlings    mechanisms    vib    belgium    leader    writing    plays    subsequent    edge    regulating    stem    deciphered    cells    biochemistry    msca    genomics    decipher    vistas    cytometry    mechanics    ma    lab    replication    organisms    ghent    plants    elongation    slu    shown    yuan    mentoring    flow    cellular    folding    apical    signals    wall    young    theoretical    aring    receive    hypothesized    secondments    ambition    experimental    developmental    poorly    plant    rigid    follow    fellowship    biology    endoreduplication    sweden    gained    elucidation    outstanding    scientist    damage    environments    successful    achievement    force    hormonal    tissue    personalized    researcher    critical    hook   

Project "MendoFold" data sheet

The following table provides information about the project.

Coordinator
SVERIGES LANTBRUKSUNIVERSITET 

Organization address
address: ALMAS ALLE 8
city: UPPSALA
postcode: 750 07
website: http://www.slu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SVERIGES LANTBRUKSUNIVERSITET SE (UPPSALA) coordinator 203˙852.00

Map

 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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