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COMMiT SIGNED
Cancer Organoids Multiplexed Screening in Microfluidic Textile chips
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0COMMiT project word cloud
Explore the words cloud of the COMMiT project. It provides you a very rough idea of what is the project "COMMiT" about.
cello
breakthrough
industrialization
textile
trials
tested
tumor
reduce
single
content
encapsulated
replace
revolutionizing
prepare
models
generate
1000
screening
democratization
invented
droplets
cell
market
care
micro
screen
techniques
leads
size
fabrication
explosion
personalization
chips
notably
cancer
ercadg
animal
world
precision
calls
flow
biology
limited
throughput
microfluidics
assay
power
paradigm
overcome
anticancer
solution
turn
time
conventional
drug
samples
context
microfluidic
spheroids
fftc
proving
ranging
panels
combinations
first
3d
societal
laboratories
diagnosis
affordable
versus
treatment
individual
organs
pave
treatments
tens
point
personalized
automated
platform
consumption
industry
barrier
minute
route
medicine
pharmaceutical
clinical
nanoliter
free
drugs
resolution
biopsy
technological
chip
commit
Project "COMMiT" data sheet
The following table provides information about the project.
| Coordinator |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Organization address contact info |
| Coordinator Country | France [FR] |
| Total cost | 0 € |
| EC max contribution | 150˙000 € (0%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2019-PoC |
| Funding Scheme | ERC-POC-LS |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-09-01 to 2022-02-28 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | coordinator | 150˙000.00 |
Map
Project objective
The development of precision and personalized medicine, notably in cancer, leads to an explosion in the cost of research, clinical trials, diagnosis and treatment. It calls for a change of paradigm in cell-based personalized models, allowing-high throughput screening of large panels of drugs at low cost and on minute samples. We invented in ERCadg CellO a new technology “Free-Flow Textile Chips” (FFTC) proving a solution to the above problem. It allows the production of high-resolution complex microfluidic devices at very low cost using the power of the textile industry. Using this technology we developed an automated platform able to generate, from a single micro-biopsy, a large number of 3D tumor cell spheroids encapsulated within individual nanoliter droplets, and to screen them against tens of drug combinations. This platform will reduce the time, sample size, cost of screening and drugs consumption per assay by factors ranging from 10 to 1000. This will in turn replace animal testing, and allow low-cost high-content drug screening and affordable precision medicine. This new platform will be tested versus conventional techniques in a real world context, and steps towards industrialization will be taken. We shall first target the market of research laboratories and drug development in the pharmaceutical industry, but also prepare clinical applications to the personalization of anticancer treatments. Beyond this, FFTC represents a major breakthrough in microfluidics, a technological field that is currently revolutionizing biology and medicine. Currently its democratization and societal impact are limited by fabrication costs. FFTC will overcome this barrier. COMMiT will thus pave the route to a wide range of other applications, such as “point-of-care” devices or “organs-on-chip” to replace animal testing.
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The information about "COMMIT" are provided by the European Opendata Portal: CORDIS opendata.
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lastchecktime (2024-10-08 18:10:42) correctly updated