FLOWGENE

Following the Genomic Footprints of Early Europeans

 Coordinatore UPPSALA UNIVERSITET 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore Sweden [SE]
 Totale costo 1˙500˙000 €
 EC contributo 1˙500˙000 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2012-StG_20111109
 Funding Scheme ERC-SG
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-10-01   -   2017-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UPPSALA UNIVERSITET

 Organization address address: SANKT OLOFSGATAN 10 B
city: UPPSALA
postcode: 751 05

contact info
Titolo: Dr.
Nome: Bo Mattias
Cognome: Jakobsson
Email: send email
Telefono: +46 18 4716449
Fax: +46 18 4716310

SE (UPPSALA) hostInstitution 1˙500˙000.00
2    UPPSALA UNIVERSITET

 Organization address address: SANKT OLOFSGATAN 10 B
city: UPPSALA
postcode: 751 05

contact info
Titolo: Mrs.
Nome: Frida
Cognome: Svedbergh
Email: send email
Telefono: +46 18 471 2867

SE (UPPSALA) hostInstitution 1˙500˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

material    modern    human    tools    theory    genomes    temporal    full    recent    demographic    data    history    complete    time    population    prehistory    ancient    evolutionary    variation    dna    genomic    revolution    genetic    genome   

 Obiettivo del progetto (Objective)

'Two of greatest challenges of the post-genomic era are to (i) develop a detailed understanding of the heritable variation in the human genome, and to (ii) determine which key events in human evolutionary history that are responsible for patterns of genomic variation. The recent genomic revolution will be instrumental in these quests and we will very soon have access to several thousand complete genomes from diverse populations.

Extracting genetic information from ancient material has for long been hampered by numerous difficulties after its first steps some two decades ago, but in the last few years, many of these problems have been solved and the use of ancient DNA is now beginning to show its full potential. The use of ancient DNA has been announced among the top-ten ‘insights of the decade’ by Science, and promises to transform our views on human origins and prehistory.

The demographic history of Europeans attracts great interest in archaeology, anthropology, and human genetics, and it has drawn extensive research focus for more than a century. The recent genomic revolution has opened up the time dimension for genomic analyses, however, to harness the full potential of genomic data from modern and ancient material, we need new population genetic theory and modern statistical analysis tools. I propose to conduct 3 Ancient Genome Projects to generate complete genomes for multiple individuals from 3 time epochs in the European prehistory; the Cro-Magnon-, the Mesolithic-, and the Neolithic-Genome project. These Genome Projects will proceed in concert with development a) new population genetic theory and novel tools for demographic inference, b) a novel, temporal based, framework for characterizing selection and local adaptation, and c) explore the evolutionary history of gene-variants associated with traits and diseases. Genomic data from temporal samples has the potential to revolutionize our understanding of human evolution and the demographic history of Europe.'

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