XNA

Development of an artificial information system

 Coordinatore KATHOLIEKE UNIVERSITEIT LEUVEN 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore Belgium [BE]
 Totale costo 2˙500˙000 €
 EC contributo 2˙500˙000 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2012-ADG_20120216
 Funding Scheme ERC-AG
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-04-01   -   2018-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITE D'EVRY-VAL D'ESSONNE

 Organization address address: BOULEVARD FRANCOIS MITTERAND 23 1
city: EVRY
postcode: 91025

contact info
Titolo: Mrs.
Nome: Corine
Cognome: Le Grand
Email: send email
Telefono: +33 1 69 47 90 57

FR (EVRY) beneficiary 595˙360.00
2    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Dr.
Nome: Elke
Cognome: Lammertyn
Email: send email
Telefono: +32 16 32 06 21
Fax: +32 16 32 06 21

BE (LEUVEN) hostInstitution 1˙904˙640.00
3    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Prof.
Nome: Piet
Cognome: Herdewyn
Email: send email
Telefono: +32 16 337387
Fax: +32 16 337340

BE (LEUVEN) hostInstitution 1˙904˙640.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

natural    biology    nucleic    therapeutics    orthogonal    acids    become    first    synthesize    synthetic    genetic    artificial   

 Obiettivo del progetto (Objective)

'Artificial genetic sequences have become an important tool for the development of new therapeutics but may also define a trait of technological innovation. The possibility to synthesize genes, plasmids and chromosomes combined with the possibilities of directed mutagenesis and genetically reprogramming organisms and directing their evolution will become a crucial issue in synthetic biology. The uniformity of genetic alphabets, the universality of the genetic code, the ubiquity of genetic interchanges and the risks of genetic pollution cannot be overlooked. On the other hand, synthetic nucleic acids will become more and more important as potential new drugs. It is proposed to develop an additional type of nucleic acids for the use as information system for the propagation of specific information of non-natural origin. It is the aim of the project to contribute to the development of an artificial genetic system orthogonal to the natural system that can be used as well in synthetic biology as in medicine. Therefore we have to select & develop the appropriate chemical and enzymatic tools. This means (chemically) the selection of unnatural nucleic acids, their precursors and their modification for uptake in bacteria. Specialized polymerases as well as ligases will need to be developed for this purpose. The goal of the project is to design and synthesize a first orthogonal plasmid and new series of aptamers. A first application is the production of new therapeutics. This is a multidisciplinary project involving mainly chemistry and biotechnology. The general project architecture is to explore experimental progress in vivo and in vitro to reach the final assembly of an XNA episome.'

Altri progetti dello stesso programma (FP7-IDEAS-ERC)

SIMP (2008)

Ultra-high-Q Physics: Towards single molecules and phonons

Read More  

EVOBREED (2013)

Evolutionary strategy for plant breeding

Read More  

IN-AFRICA (2012)

IN AFRICA: THE ROLE OF EAST AFRICA IN THE EVOLUTION OF HUMAN DIVERSITY

Read More