PARENTAL AGE EFFECTS

Epigenetic transgenerational Effects of Parental Age on Fitness

 Coordinatore MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. 

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Mr.
Nome: Thomas
Cognome: Dzionsko
Email: send email
Telefono: +49 8157 932 202
Fax: +49 8157 932 214

 Nazionalità Coordinatore Germany [DE]
 Totale costo 100˙000 €
 EC contributo 100˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-CIG
 Funding Scheme MC-CIG
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-08-01   -   2017-07-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Mr.
Nome: Thomas
Cognome: Dzionsko
Email: send email
Telefono: +49 8157 932 202
Fax: +49 8157 932 214

DE (MUENCHEN) coordinator 100˙000.00

Mappa


 Word cloud

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offspring    affect    wild    evolution    grand    sparrows    parental    longevity    individual    fitness    age    evolutionary    epigenetic    population    lifespan    models   

 Obiettivo del progetto (Objective)

'Why do organisms age? This is one of the big, unsolved questions in biology, because it is unclear how a process that decreases fitness can persist evolutionarily, and why species do not evolve to live longer. Many evolutionary theories have been suggested to explain, but it is likely that multiple factors contribute to the phenomenon. One potentially very important factor has been largely ignored: transgenerational epigenetic effects of senescence. Epigenetic effects can strongly affect the predictions of evolutionary models. One such epigenetic, trans-generational factor that affects fitness is parental age. It has been known for nearly a century that a mother's age can affect her offspring's, and even her grand- offspring's fitness. However, all studies have been done in the laboratory. Therefore, it is unknown whether the effect of parental age operates in wild populations, and how it contributes to our understanding of the evolution of longevity. We propose to study the effects of parental and grand-parental age on their offspring's lifespan, reproductive success, physiology and genetics in a wild population of house sparrows. We have data available from a long-term study of sparrows in which we will examine these topics in detail. Only a closed population such as the one that we is uniquely suited for this study, as we can accurately estimate lifespan, fitness and parentage, which are all prerequisites for the longitudinal study of longevity on individual fitness. Also, we will use focused experiments with captive birds to cement our hypotheses, and individual-based simulation models to explore the implications of parental age effects on the evolution of longevity.'

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