CHROMAPHY

Structural preferences of histone variants during chromatin assembly in Physarum polycephalum

 Coordinatore LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN 

 Organization address address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539

contact info
Titolo: Dr.
Nome: Corey
Cognome: Laverty
Email: send email
Telefono: +49 89 2180 77095
Fax: +49 89 2180 77093

 Nazionalità Coordinatore Germany [DE]
 Totale costo 161˙968 €
 EC contributo 161˙968 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-01-01   -   2015-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

 Organization address address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539

contact info
Titolo: Dr.
Nome: Corey
Cognome: Laverty
Email: send email
Telefono: +49 89 2180 77095
Fax: +49 89 2180 77093

DE (MUENCHEN) coordinator 161˙968.80

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

organisms    polycephalum    physarum    biology    chromaphy    human    epigenetic    cell    genes    proteins   

 Obiettivo del progetto (Objective)

'One of the main challenges of 21st century biology is to describe the many factors controlling our genes – our ‘epigenetics’. Having sequenced the human genome in 1999, and the genomes of many other organisms since then, we already know what genes these organisms have, but we must now study where those genes are used, in which cell types, during which stage of development, and in response to what environmental factors. This ‘epigenetic’ knowledge is crucial to the understanding of development and disease. Current models in this field can demonstrate that epigenetic information is passed through generations, but they cannot fully explain how the information is inherited. The ChromaPhy project studies the mechanisms of epigenetic inheritance. We combine novel techniques of chemical biology and live-cell imaging with those of molecular genetics, in the model organism Physarum polycephalum. Physarum has a unique ability to absorb whole proteins from its environment into its cellular physiology, making it ideal for our study. ChromaPhy brings together four research groups in Germany and France to support and enable the UK-trained researcher. Because chromatin components are some of the most highly conserved proteins in nature, discoveries we learn from Physarum polycephalum will be directly applicable to human biology.'

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