TRANSMEM

Fast transformation between episodic and semantic memories: Interactions between the hippocampal formation and related regions and their breakdown in Alzheimer’s disease

 Coordinatore UNIVERSITY OF SUSSEX 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 1˙169˙788 €
 EC contributo 1˙169˙788 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2013-StG
 Funding Scheme ERC-SG
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-02-01   -   2019-01-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITY OF SUSSEX

 Organization address address: Sussex House
city: FALMER, BRIGHTON
postcode: BN1 9RH

contact info
Titolo: Dr.
Nome: Christopher
Cognome: Bird
Email: send email
Telefono: +44 1273 876816
Fax: +44 1273 678058

UK (FALMER, BRIGHTON) hostInstitution 1˙169˙788.00
2    UNIVERSITY OF SUSSEX

 Organization address address: Sussex House
city: FALMER, BRIGHTON
postcode: BN1 9RH

contact info
Titolo: Dr.
Nome: Sui-Mee
Cognome: Chan
Email: send email
Telefono: +44 1273 873448
Fax: +44 1273 678192

UK (FALMER, BRIGHTON) hostInstitution 1˙169˙788.00

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brain    hf    semantic    experimental    theories    transmem    memories    episodic    regions    mind    events    time    ad    memory    human   

 Obiettivo del progetto (Objective)

'Our memories define who we are and allow us to live independently. Conscious memory is commonly split into two components; “episodic memory” for events that are specific in time and place, and “semantic memory” for our conceptual knowledge about the world. The acquisition of both episodic and semantic memories depends upon the hippocampal formation (HF) and its interactions with other brain regions. Disruption to this brain system causes dramatic memory impairment, notably in the case of Alzheimer’s disease (AD). Current theories propose that episodic and semantic memory are either neuroanatomically inseparable, are independent, or that there is a gradual transformation from episodic to semantic over time. These theories fail to account for experimental evidence demonstrating the dynamic nature of human memory. TRANSMEM comprises a series of experiments designed to test a novel hypothesis; that semantic memory comprises high-level “structures” as well as “elements”, and memories for events are rapidly transformed between episodic and semantic representations and vice versa. In doing so, TRANSMEM will answer fundamental questions about the human mind, such as “Why do we remember certain things but not others?”, and “How do we store and retrieve our memories for the past?” Innovative methods, including the use of video clips and virtual reality, will be used to investigate memory for realistic materials. In a fully interdisciplinary approach, I will employ cutting-edge fMRI techniques and neuropsychology to establish how the HF interacts with other brain regions to mediate these transformations and how these processes break down in AD. Completion of the TRANSMEM project will lead to major advances in research and practice in experimental and clinical psychology, cognitive and behavioural neuroscience, neurology, and will be of interest to all scholars of the complexities of human mind.'

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