INDUHEART

Induced pluripotent stem cells for cardiomyocyte generation in mouse

 Coordinatore BIOTALENTUM TUDASFEJLESZTO KFT 

 Organization address address: AULICH LAJOS UTCA 26
city: GOEDOELLO
postcode: 2100

contact info
Titolo: Prof.
Nome: András
Cognome: Dinnyés
Email: send email
Telefono: +36 20 510 9632
Fax: -669

 Nazionalità Coordinatore Hungary [HU]
 Totale costo 100˙000 €
 EC contributo 100˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-IRG-2008
 Funding Scheme MC-IRG
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-03-16   -   2013-03-15

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    BIOTALENTUM TUDASFEJLESZTO KFT

 Organization address address: AULICH LAJOS UTCA 26
city: GOEDOELLO
postcode: 2100

contact info
Titolo: Prof.
Nome: András
Cognome: Dinnyés
Email: send email
Telefono: +36 20 510 9632
Fax: -669

HU (GOEDOELLO) coordinator 100˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

es    stem    cardiac    embryonic    cell    ips    generation    mouse    cells    cardiomyocytes    differentiation    induheart   

 Obiettivo del progetto (Objective)

'The scientific aim of InduHeart is to produce novel comparative information on the generation, maintenance, characteristics of iPS cells in mouse and on their differentiation towards the cardiac lineage. InduHeart will also employ mouse embryonic stem (ES) cell lines to develop innovative methods for the targeted preparation of differentiated cardiac muscle cells. The characteristics of cardiomyocytes generated from iPS and Embryonic Stem (ES) cells will be compared and their ability to report disease phenotypes and drug responses faithfully will be investigated. Technical focus will be generating a novel and potentially patentable technology in Europe for reprogramming somatic cells to an embryonic state without the use of viral constructs, which have a perceived risk for future cell based therapy. This will lead towards the generation of iPS cells in a more predictable, controlled and safer way than previously. Overall, the results are expected to provide novel information on the pathways and differentiation events leading to a high percentage of cardiomyocytes in the special supplement based mouse ES cell differentiation system. These cardiomyocytes can serve also as useful tools for high-throughput screenings for pharmacological studies including efficacy, safety, and toxicology. InduHeart will contribute to the field of modern tissue engineering and regenerative medicine.'

Altri progetti dello stesso programma (FP7-PEOPLE)

BFLDS (2012)

"Direct Imaging of Budding and Fusion of Lipid Droplets Mediated by Proteins in Emulsion Droplets Based on Microfluidics - Dynamics of Proteins Interactions, Assembly and Metabolism Energy"

Read More  

LCMVACC (2012)

Prophylactic and therapeutic use of recombinant lymphocytic choriomeningitis virus against melanoma

Read More  

BIMATH (2011)

Brain and Behavior of Math Cognition in bilinguals. Implications for dyscalculia

Read More