PARVIRDIS

Enhancing natural wastewater treatment systems: the role of particles in sunlight-mediated virus inactivation

 Coordinatore ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE 

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Tamar
Cognome: Kohn
Email: send email
Telefono: +41 21 693 0891
Fax: -

 Nazionalità Coordinatore Switzerland [CH]
 Totale costo 188˙793 €
 EC contributo 188˙793 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2007-4-2-IIF
 Funding Scheme MC-IIF
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-07-01   -   2010-06-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Tamar
Cognome: Kohn
Email: send email
Telefono: +41 21 693 0891
Fax: -

CH (LAUSANNE) coordinator 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

wetland    waters    surface    adsorption    photoreactive    treatment    onto    virus    viral    sunlight    inactivation    viruses    efficiency    natural    ros    destruction    exposed    particles    constructed   

 Obiettivo del progetto (Objective)

'The processes by which viruses are inactivated in sunlight-exposed surface waters remains largely unknown. This lack of information severely limits our ability to predict the efficiency of and rationally design natural treatment systems that utilize sunlight-mediated inactivation (e.g., constructed wetlands). Viruses commonly associate with particles in surface waters, including photoreactive particles that can 1) adsorb viruses and 2) produce reactive oxygen species (ROS) when exposed to sunlight. Virus adsorption onto the surface of photoreactive particles exposes them to elevated ROS concentration and may increase inactivation compared to free viruses. The goal of this research is to characterize the adsorption and inactivation of particle-associated viruses in the dark and exposed to sunlight, with the aim of predicting the fate of viral pathogens within natural systems and using this information to improve their efficiency. We will quantify how different viral characteristics (e.g., isoelectric points, capsid size and composition, genome type) influence adsorption and inactivation, and which modes of inactivation are dominant (e.g., ROS damage to viral host binding sites, destruction of viral capsids by ROS or adsorption, and modification or destruction of genomic nucleic acids by ROS or nucleases). To aid in this study, a novel qPCR-based method for determining virus viability will be developed, a tool that will be of use for a variety of fields including environmental microbiology, public health and medicine. The detailed information gathered in this study will then guide the development of methods to improve the viral removal efficiency of a highly controllable constructed wetland. Different wetland configurations will be tested to promote virus adsorption onto iron-oxide coated sand and to maximize viral exposure to ROS. In so doing, this project will increase the efficacy of low-cost, effective systems for water and wastewater treatment.'

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