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Personalized PREvention of Chronic DIseases

Total Cost €


EC-Contrib. €






Project "PRECeDI" data sheet

The following table provides information about the project.


Organization address
address: Largo Agostino Gemelli 1
city: MILANO
postcode: 20123

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website
 Total cost 792˙000 €
 EC max contribution 792˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2014
 Funding Scheme MSCA-RISE
 Starting year 2015
 Duration (year-month-day) from 2015-01-01   to  2018-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
4    DEBRECENI EGYETEM HU (DEBRECEN) participant 90˙000.00
5    STICHTING VUMC NL (AMSTERDAM) participant 63˙000.00
6    BETTER VALUE HEALTHCARE LTD UK (OXFORD) participant 58˙500.00
9    Myriad Genetics Srl IT (Milano) participant 0.00
10    STICHTING VU NL (AMSTERDAM) participant 0.00


 Project objective

The aim of the Personalized pREvention of Chronic DIseases consortium (PRECeDI) is to provide high-quality, multidisciplinary knowledge through training and research in Personalized Medicine (PM), with specific reference to prevention of chronic diseases. There is a large consensus that PM is a driver of innovation for research and health care, and also for the health care system and industry as a whole. In order to harness the potential of this new concept, the PRECeDI consortium provides a cohesive framework for training staff from academic and non-academic (NA) institutions on research topics related to PM, with specific reference to the prevention of chronic diseases where there is a lack of substantial evidence, though the potential is huge. The acquisition of skills from staff will come from dedicated secondments aimed at training on research topics not available at the home institutions, and attendance to courses, workshops, seminars, conferences. The goal of secondment is to enable staff to make informed decisions for appropriately serve health care systems, new biotech industries and policy makers at the dawn of the post-genomic era PRECeDI is a multidisciplinary group of institutions working on different facets of PM, from basic research, to economic evaluations, health service organization, and ethical, social, and policy issues. The consortium is embedded in existing cooperation structures, such as the PerMed project and the Erasmus Mundus ERAWEB II program, with additional leading SMEs in Europe and Canada as beneficiaries. The consortium consists of 8 beneficiaries and 3 partners, of which 7 are academic institutions and 4 NA, including 2 SMEs. During 4-years, 23 ESRs and 7 ERs will be seconded to 11 institutions, where researchers will be supported by a team of leading EU scientists in PM-related disciplines. In the long run, PRECeDI will foster the integration of PM in the field of prevention, thus contributing to better health for Europe’s citizen


List of deliverables.
Common Guidelines on Personalised Medicine Documents, reports 2019-07-23 10:52:54
Scientific Publications Documents, reports 2019-07-23 10:52:54
Report on open workshop “Policy Development in PM” Documents, reports 2019-07-23 10:52:54
Final Conference Other 2019-07-23 10:52:54
Workshop on “Policy Development in PM” Other 2019-07-23 10:52:54
Website Websites, patent fillings, videos etc. 2019-07-23 10:52:52
Report on Seminar Personalised Medicine 2020 and Beyond Documents, reports 2019-07-23 10:52:52
Seminar Personalised Medicine 2020 and Beyond Other 2019-07-23 10:52:52

Take a look to the deliverables list in detail:  detailed list of PRECeDI deliverables.


year authors and title journal last update
List of publications.
2018 Erica Pitini, Corrado De Vito, Carolina Marzuillo, Elvira D’Andrea, Annalisa Rosso, Antonio Federici, Emilio Di Maria, Paolo Villari
How is genetic testing evaluated? A systematic review of the literature
published pages: 605-615, ISSN: 1018-4813, DOI: 10.1038/s41431-018-0095-5
European Journal of Human Genetics 26/5 2019-07-23
2017 Alessia Tognetto, Maria Benedetta Michelazzo, Giovanna Elisa Calabró, Brigid Unim, Marco Di Marco, Walter Ricciardi, Roberta Pastorino, Stefania Boccia
A Systematic Review on the Existing Screening Pathways for Lynch Syndrome Identification
published pages: , ISSN: 2296-2565, DOI: 10.3389/fpubh.2017.00243
Frontiers in Public Health 5 2019-07-23
2018 Szilvia Fiatal, Róza Ádány
Application of Single-Nucleotide Polymorphism-Related Risk Estimates in Identification of Increased Genetic Susceptibility to Cardiovascular Diseases: A Literature Review
published pages: , ISSN: 2296-2565, DOI: 10.3389/fpubh.2017.00358
Frontiers in Public Health 5 2019-07-23
2018 Emanuele Leoncini, Vladimir Vukovic, Gabriella Cadoni, Luca Giraldi, Roberta Pastorino, Dario Arzani, Livia Petrelli, Victor Wünsch-Filho, Tatiana Natasha Toporcov, Raquel Ayub Moyses, Keitaro Matsuo, Cristina Bosetti, Carlo La Vecchia, Diego Serraino, Lorenzo Simonato, Franco Merletti, Paolo Boffetta, Mia Hashibe, Yuan-Chin Amy Lee, Stefania Boccia
Tumour stage and gender predict recurrence and second primary malignancies in head and neck cancer: a multicentre study within the INHANCE consortium
published pages: 1205-1218, ISSN: 0393-2990, DOI: 10.1007/s10654-018-0409-5
European Journal of Epidemiology 33/12 2019-07-23
2018 Elvira D’Andrea, Tyra Lagerberg, Corrado De Vito, Erica Pitini, Carolina Marzuillo, Azzurra Massimi, Maria Rosaria Vacchio, Paola Grammatico, Paolo Villari
Patient experience and utility of genetic information: a cross-sectional study among patients tested for cancer susceptibility and thrombophilia
published pages: , ISSN: 1018-4813, DOI: 10.1038/s41431-017-0083-1
European Journal of Human Genetics 2019-07-23
2017 9. Rosso A, Pitini E, D\'Andrea E, Massimi A, De Vito C, Marzuillo C, Villari P.
The Cost-effectiveness of Genetic Screening for Familial Hypercholesterolemia: a Systematic Review.
published pages: , ISSN: 1120-9135, DOI: 10.7416/ai.2017.2178
Ann Ig 2019-07-23
2018 Roberta Pastorino, Anna Puggina, Robert Carreras-Torres, Pagona Lagiou, Ivana Holcátová, Lorenzo Richiardi, Kristina Kjaerheim, Antonio Agudo, Xavier Castellsagué, Tatiana V. Macfarlane, Luigi Barzan, Cristina Canova, Nalin S. Thakker, David I. Conway, Ariana Znaor, Claire M. Healy, Wolfgang Ahrens, David Zaridze, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Eleonora Fabianova, Ioan Nicolae Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paul Brennan, Valérie Gaborieau, James D. McKay, Stefania Boccia
Genetic Contributions to The Association Between Adult Height and Head and Neck Cancer: A Mendelian Randomization Analysis
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-22626-w
Scientific Reports 8/1 2019-07-23
2016 Elvira D’Andrea, Carolina Marzuillo, Corrado De Vito, Marco Di Marco, Erica Pitini, Maria Rosaria Vacchio, Paolo Villari
Which BRCA genetic testing programs are ready for implementation in health care? A systematic review of economic evaluations
published pages: 1171-1180, ISSN: 1098-3600, DOI: 10.1038/gim.2016.29
Genetics in Medicine 18/12 2019-07-23
2018 Sven J. van der Lee, Charlotte E. Teunissen, René Pool, Martin J. Shipley, Alexander Teumer, Vincent Chouraki, Debora Melo van Lent, Juho Tynkkynen, Krista Fischer, Jussi Hernesniemi, Toomas Haller, Archana Singh-Manoux, Aswin Verhoeven, Gonneke Willemsen, Francisca A. de Leeuw, Holger Wagner, Jenny van Dongen, Johannes Hertel, Kathrin Budde, Ko Willems van Dijk, Leonie Weinhold, M. Arfan Ikram, Maik Pietzner, Markus Perola, Michael Wagner, Nele Friedrich, P. Eline Slagboom, Philip Scheltens, Qiong Yang, Robert E. Gertzen, Sarah Egert, Shuo Li, Thomas Hankemeier, Catharina E.M. van Beijsterveldt, Ramachandran S. Vasan, Wolfgang Maier, Carel F.W. Peeters, Hans Jörgen Grabe, Alfredo Ramirez, Sudha Seshadri, Andres Metspalu, Mika Kivimäki, Veikko Salomaa, Ayşe Demirkan, Dorret I. Boomsma, Wiesje M. van der Flier, Najaf Amin, Cornelia M. van Duijn
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies
published pages: 707-722, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2017.11.012
Alzheimer\'s & Dementia 14/6 2019-07-23
2017 A Rosso, E D\'Andrea, M Di Marco, E Pitini, B Unim, V Baccolini, C De Vito, C Marzuillo, MR Vacchio, F Barnhoorn, D Zeegers, P Villari
Interim results of EUPHA network members’ s survey on Public Health Genomics
published pages: , ISSN: 1101-1262, DOI: 10.1093/eurpub/ckx187.327
European Journal of Public Health 27/suppl_3 2019-07-23
2018 K Bíró, V Dombrádi, A Jani, K Boruzs, M Gray
Creating a common language: defining individualized, personalized and precision prevention in public health
published pages: , ISSN: 1741-3842, DOI: 10.1093/pubmed/fdy066
Journal of Public Health 2019-07-23
2018 Marco Di Marco, Elvira D’Andrea, Paolo Villari
Universal screening of Lynch syndrome is ready for implementation
published pages: , ISSN: 1098-3600, DOI: 10.1038/s41436-018-0027-3
Genetics in Medicine 2019-07-23
2016 B Unim, T Lagerberg, G Adamo, E Pitini, E D’Andrea, MR Vacchio, C De Vito, P Villari
Delivery models for predictive genetic testing: preliminary results of a systematic review
published pages: , ISSN: 1101-1262, DOI: 10.1093/eurpub/ckw169.043
European Journal of Public Health 26/suppl_1 2019-07-23
2018 Sven J van der Lee, Frank J Wolters, M Kamran Ikram, Albert Hofman, M Arfan Ikram, Najaf Amin, Cornelia M van Duijn
The effect of APOE and other common genetic variants on the onset of Alzheimer\'s disease and dementia: a community-based cohort study
published pages: 434-444, ISSN: 1474-4422, DOI: 10.1016/s1474-4422(18)30053-x
The Lancet Neurology 17/5 2019-07-23
2018 Juho Tynkkynen, Vincent Chouraki, Sven J. van der Lee, Jussi Hernesniemi, Qiong Yang, Shuo Li, Alexa Beiser, Martin G. Larson, Katri Sääksjärvi, Martin J. Shipley, Archana Singh-Manoux, Robert E. Gerszten, Thomas J. Wang, Aki S. Havulinna, Peter Würtz, Krista Fischer, Ayse Demirkan, M. Arfan Ikram, Najaf Amin, Terho Lehtimäki, Mika Kähönen, Markus Perola, Andres Metspalu, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, Ramachandran S. Vasan, Mika Kivimäki, Cornelia M. van Duijn, Sudha Seshadri, Veikko Salomaa
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer\'s disease: A prospective study in eight cohorts
published pages: 723-733, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.01.003
Alzheimer\'s & Dementia 14/6 2019-07-23
2017 Jun Liu, Sabina Semiz, Sven J. van der Lee, Ashley van der Spek, Aswin Verhoeven, Jan B. van Klinken, Eric Sijbrands, Amy C. Harms, Thomas Hankemeier, Ko Willems van Dijk, Cornelia M. van Duijn, AyÅŸe Demirkan
Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study
published pages: , ISSN: 1573-3882, DOI: 10.1007/s11306-017-1239-2
Metabolomics 13/9 2019-07-23
2018 Adrienne Tin, Yong Li, Jennifer A. Brody, Teresa Nutile, Audrey Y. Chu, Jennifer E. Huffman, Qiong Yang, Ming-Huei Chen, Cassianne Robinson-Cohen, Aurélien Macé, Jun Liu, Ayşe Demirkan, Rossella Sorice, Sanaz Sedaghat, Melody Swen, Bing Yu, Sahar Ghasemi, Alexanda Teumer, Peter Vollenweider, Marina Ciullo, Meng Li, André G. Uitterlinden, Robert Kraaij, Najaf Amin, Jeroen van Rooij, Zoltán Kutalik, Abbas Dehghan, Barbara McKnight, Cornelia M. van Duijn, Alanna Morrison, Bruce M. Psaty, Eric Boerwinkle, Caroline S. Fox, Owen M. Woodward, Anna Köttgen
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-06620-4
Nature Communications 9/1 2019-07-23
2017 Martina C. Cornel, Carla G. van El
Barriers and Facilitating Factors for Implementation of Genetic Services: A Public Health Perspective
published pages: , ISSN: 2296-2565, DOI: 10.3389/fpubh.2017.00195
Frontiers in Public Health 5 2019-07-23
2017 Brigid Unim, Tyra Lagerberg, Erica Pitini, Corrado De Vito, Maria Rosaria Vacchio, Giovanna Adamo, Annalisa Rosso, Elvira D’Andrea, Carolina Marzuillo, Paolo Villari
Identification of Delivery Models for the Provision of Predictive Genetic Testing in Europe: Protocol for a Multicentre Qualitative Study and a Systematic Review of the Literature
published pages: , ISSN: 2296-2565, DOI: 10.3389/fpubh.2017.00223
Frontiers in Public Health 5 2019-07-23
2017 Francisca A. de Leeuw, Carel F.W. Peeters, Maartje I. Kester, Amy C. Harms, Eduard A. Struys, Thomas Hankemeier, Herman W.T. van Vlijmen, Sven J. van der Lee, Cornelia M. van Duijn, Philip Scheltens, AyÅŸe Demirkan, Mark A. van de Wiel, Wiesje M. van der Flier, Charlotte E. Teunissen
Blood-based metabolic signatures in Alzheimer\'s disease
published pages: 196-207, ISSN: 2352-8729, DOI: 10.1016/j.dadm.2017.07.006
Alzheimer\'s & Dementia: Diagnosis, Assessment & Disease Monitoring 8 2019-07-23
2017 Annalisa Rosso; Elvira D\'Andrea; Marco Di Marco; Erica Pitini; Brigid Unim; Corrado De Vito; Carolina Marzuillo; Paolo Villari
European survey on knowledge and attitudes of public health professionals on public health genomics: Pilot Study
published pages: , ISSN: 2282-0930, DOI: 10.2427/12531
Epidemiology, Biostatistics and Public Health; Vol 14, No 3 (2017) 1 2019-07-23
2018 Carla van El, Valentina Baccolini, Peter Piko, Martina Cornel
Stakeholder Views on Active Cascade Screening for Familial Hypercholesterolemia
published pages: 108, ISSN: 2227-9032, DOI: 10.3390/healthcare6030108
Healthcare 6/3 2019-07-23
2017 W. Mazzucco, R. Pastorino, T. Lagerberg, M. Colotto, E. d’Andrea, C. Marotta, C. Marzuillo, P. Villari, A. Federici, W. Ricciardi, S. Boccia
Current state of genomic policies in healthcare among EU member states: results of a survey of chief medical officers
published pages: ckw155, ISSN: 1101-1262, DOI: 10.1093/eurpub/ckw155
The European Journal of Public Health 2019-07-23
2018 Claudia Tamar Silva, Irina V. Zorkoltseva, Maartje N. Niemeijer, Marten E. van den Berg, Najaf Amin, Ayşe Demirkan, Elisa van Leeuwen, Adriana I. Iglesias, Laura B. Piñeros-Hernández, Carlos M. Restrepo, Jan A. Kors, Anatoly V. Kirichenko, Rob Willemsen, Ben A. Oostra, Bruno H. Stricker, André G. Uitterlinden, Tatiana I. Axenovich, Cornelia M. van Duijn, Aaron Isaacs
A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy
published pages: , ISSN: 1755-8794, DOI: 10.1186/s12920-018-0339-9
BMC Medical Genomics 11/1 2019-07-23
2018 Dina Vojinovic, Sven J. van der Lee, Cornelia M. van Duijn, Meike W. Vernooij, Maryam Kavousi, Najaf Amin, AyÅŸe Demirkan, M. Arfan Ikram, Aad van der Lugt, Daniel Bos
Metabolic profiling of intra- and extracranial carotid artery atherosclerosis
published pages: 60-65, ISSN: 0021-9150, DOI: 10.1016/j.atherosclerosis.2018.03.015
Atherosclerosis 272 2019-07-23
2018 Elvira D’Andrea, Tyra Lagerberg, Corrado De Vito, Erica Pitini, Carolina Marzuillo, Azzurra Massimi, Maria Rosaria Vacchio, Paola Grammatico, Paolo Villari
Correction: Patient experience and utility of genetic information: a cross-sectional study among patients tested for cancer susceptibility and thrombophilia
published pages: 1398-1398, ISSN: 1018-4813, DOI: 10.1038/s41431-018-0186-3
European Journal of Human Genetics 26/9 2019-07-23
2015 Stefania Boccia , Roberta Pastorino
Personalized PREvention of Chronic DIseases (PRECeDI):a Marie Curie RISE project
published pages: , ISSN: 2282-0930, DOI: 10.2427/18993
Epidemiology Biostatistics and Public Health - 2015, Volume 12, Number 2 2019-07-23
2017 L Giraldi, E Leoncini, R Pastorino, V Wünsch-Filho, M de Carvalho, R Lopez, G Cadoni, D Arzani, L Petrelli, K Matsuo, C Bosetti, C La Vecchia, W Garavello, J Polesel, D Serraino, L Simonato, C Canova, L Richiardi, P Boffetta, M Hashibe, Y C A Lee, S Boccia
Alcohol and cigarette consumption predict mortality in patients with head and neck cancer: a pooled analysis within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium
published pages: 2843-2851, ISSN: 0923-7534, DOI: 10.1093/annonc/mdx486
Annals of Oncology 28/11 2019-07-23
2017 Giuseppe Migliara, Valentina Baccolini, Annalisa Rosso, Elvira D’Andrea, Azzurra Massimi, Paolo Villari, Corrado De Vito
Familial Hypercholesterolemia: A Systematic Review of Guidelines on Genetic Testing and Patient Management
published pages: , ISSN: 2296-2565, DOI: 10.3389/fpubh.2017.00252
Frontiers in Public Health 5 2019-07-23
2017 Jun Liu, Jan Bert van Klinken, Sabina Semiz, Ko Willems van Dijk, Aswin Verhoeven, Thomas Hankemeier, Amy C. Harms, Eric Sijbrands, Nuala A. Sheehan, Cornelia M. van Duijn, AyÅŸe Demirkan
A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes
published pages: 2915-2926, ISSN: 0012-1797, DOI: 10.2337/db17-0199
Diabetes 66/11 2019-07-23
2018 Vladimir Vukovic, Jovana Stojanovic, Alessia Vecchioni, Roberta Pastorino, Stefania Boccia
Systematic Review and Meta-analysis of SNPs from Genome-Wide Association Studies of Head and Neck Cancer
published pages: 615-624, ISSN: 0194-5998, DOI: 10.1177/0194599818792262
Otolaryngology–Head and Neck Surgery 159/4 2019-07-23
2018 Marco Di Marco, Elvira D\'Andrea, Nikola Panic, Valentina Baccolini, Giuseppe Migliara, Carolina Marzuillo, Corrado De Vito, Roberta Pastorino, Stefania Boccia, Paolo Villari
Which Lynch syndrome screening programs could be implemented in the “real world”? A systematic review of economic evaluations
published pages: , ISSN: 1098-3600, DOI: 10.1038/gim.2017.244
2017 Pastorino R, Tognetto A, Boccia S
Screening Programs for Lynch Syndrome in Italy: State of the Art and Future Challenges
published pages: , ISSN: , DOI: 10.2427/12615
Epidemiology, Biostatistics and Public Health 2019-07-23

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