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YAKUT SIGNED

Genomics, epigenomics and transcriptomics of Yakutian horses, a unique domestic breed adapted to life in the Arctic

Total Cost €

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EC-Contrib. €

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Partnership

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 YAKUT project word cloud

Explore the words cloud of the YAKUT project. It provides you a very rough idea of what is the project "YAKUT" about.

country    cover    strategies    breeding    heritage    reconstruct    sound    adaptations    genomic    months    spectacular    evolutionary    found    care    genome    mysterious    amazing    controversial    origins    exceptional    northern    reveal    seasonal    first    hair    transcriptomics    tools    regulating    history    breed    levels    edge    yakut    snow    dna    capacities    despite    arctic    preserve    human    mechanisms    dataset    stables    underlying    living    ordm    horse    expression    horses    origin    time    cutting    cattle    unsurprisingly    genetic    yakutian    grazing    republic    receive    gene    responsible    epigenetic    winter    yakutia    efforts    natural    extensive    parked    hemisphere    70    temperatures    cold    modifications    deep    federation    epigenomics    coldest    life    succeeded    vegetation    environment    metabolism    people    ancient    russian    contrast    densities    genomics    record    metabolic    air    economy    sakha    domestic    extreme   

Project "YAKUT" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 200˙194 €
 EC max contribution 200˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-15   to  2017-09-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 200˙194.00

Map

 Project objective

Yakutia (Sakha Republic, Russian Federation) is the coldest country in the Northern hemisphere with winter record temperatures as low as -70ºC. Despite such extreme conditions, the Yakut people succeeded in developing an economy based on extensive horse and cattle breeding. In contrast to cattle, that are parked in stables at winter, horses do not receive much human care, living all the year in the open air and grazing on vegetation that is under deep snow cover for 7-8 months. Unsurprisingly, Yakutian horses developed amazing adaptations to life in the cold Arctic, including exceptional hair densities for domestic horses and spectacular capacities for regulating their metabolism. The origin of Yakutian horses is controversial. In the YAKUT project, we will use cutting-edge genomic tools including genomics, transcriptomics and epigenomics, together with state-of-the-art methods in ancient DNA research, to reconstruct the evolutionary history of Yakutian horses from its mysterious origins to its adaptation to life in the Arctic. Our extensive genomic dataset will provide essential information to foster efforts for developing sound management strategies to preserve this unique genetic heritage. Following seasonal gene expression levels and associated epigenetic modifications at the whole genome scale, we will reveal for the first time the mechanisms responsible for the exceptional metabolic adaptations found in Yakutian horses. Overall, the YAKUT project aims at understanding the process of natural selection underlying the adaptation of a domestic breed to life in an extreme environment.

 Publications

year authors and title journal last update
List of publications.
2016 Michela Leonardi, Pablo Librado, Clio Der Sarkissian, Mikkel Schubert, Ahmed H. Alfarhan, Saleh A. Alquraishi, Khaled A. S. Al-Rasheid, Cristina Gamba, Eske Willerslev, Ludovic Orlando
Evolutionary Patterns and Processes: Lessons from Ancient DNA
published pages: syw059, ISSN: 1063-5157, DOI: 10.1093/sysbio/syw059
Systematic Biology 2019-06-13
2016 P. Librado, A. Fages, C. Gaunitz, M. Leonardi, S. Wagner, N. Khan, K. Hanghoj, S. A. Alquraishi, A. H. Alfarhan, K. A. Al-Rasheid, C. Der Sarkissian, M. Schubert, L. Orlando
The Evolutionary Origin and Genetic Makeup of Domestic Horses
published pages: 423-434, ISSN: 0016-6731, DOI: 10.1534/genetics.116.194860
Genetics 204/2 2019-06-13

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