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YAKUT SIGNED

Genomics, epigenomics and transcriptomics of Yakutian horses, a unique domestic breed adapted to life in the Arctic

Total Cost €

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EC-Contrib. €

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Partnership

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 YAKUT project word cloud

Explore the words cloud of the YAKUT project. It provides you a very rough idea of what is the project "YAKUT" about.

history    breed    air    densities    ordm    breeding    months    vegetation    despite    care    levels    succeeded    adaptations    yakutian    unsurprisingly    extensive    living    seasonal    genomic    horses    modifications    temperatures    genetic    people    record    heritage    grazing    origins    snow    republic    winter    natural    federation    sakha    hemisphere    northern    time    domestic    cover    gene    transcriptomics    yakutia    stables    country    capacities    mechanisms    regulating    tools    expression    responsible    hair    arctic    economy    horse    found    mysterious    spectacular    life    amazing    genomics    deep    coldest    preserve    efforts    exceptional    parked    origin    receive    yakut    extreme    contrast    dataset    controversial    first    epigenetic    epigenomics    edge    reconstruct    underlying    evolutionary    environment    cattle    strategies    russian    metabolism    cutting    dna    ancient    sound    genome    70    human    cold    metabolic    reveal   

Project "YAKUT" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 200˙194 €
 EC max contribution 200˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-15   to  2017-09-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 200˙194.00

Map

 Project objective

Yakutia (Sakha Republic, Russian Federation) is the coldest country in the Northern hemisphere with winter record temperatures as low as -70ºC. Despite such extreme conditions, the Yakut people succeeded in developing an economy based on extensive horse and cattle breeding. In contrast to cattle, that are parked in stables at winter, horses do not receive much human care, living all the year in the open air and grazing on vegetation that is under deep snow cover for 7-8 months. Unsurprisingly, Yakutian horses developed amazing adaptations to life in the cold Arctic, including exceptional hair densities for domestic horses and spectacular capacities for regulating their metabolism. The origin of Yakutian horses is controversial. In the YAKUT project, we will use cutting-edge genomic tools including genomics, transcriptomics and epigenomics, together with state-of-the-art methods in ancient DNA research, to reconstruct the evolutionary history of Yakutian horses from its mysterious origins to its adaptation to life in the Arctic. Our extensive genomic dataset will provide essential information to foster efforts for developing sound management strategies to preserve this unique genetic heritage. Following seasonal gene expression levels and associated epigenetic modifications at the whole genome scale, we will reveal for the first time the mechanisms responsible for the exceptional metabolic adaptations found in Yakutian horses. Overall, the YAKUT project aims at understanding the process of natural selection underlying the adaptation of a domestic breed to life in an extreme environment.

 Publications

year authors and title journal last update
List of publications.
2016 Michela Leonardi, Pablo Librado, Clio Der Sarkissian, Mikkel Schubert, Ahmed H. Alfarhan, Saleh A. Alquraishi, Khaled A. S. Al-Rasheid, Cristina Gamba, Eske Willerslev, Ludovic Orlando
Evolutionary Patterns and Processes: Lessons from Ancient DNA
published pages: syw059, ISSN: 1063-5157, DOI: 10.1093/sysbio/syw059
Systematic Biology 2019-06-13
2016 P. Librado, A. Fages, C. Gaunitz, M. Leonardi, S. Wagner, N. Khan, K. Hanghoj, S. A. Alquraishi, A. H. Alfarhan, K. A. Al-Rasheid, C. Der Sarkissian, M. Schubert, L. Orlando
The Evolutionary Origin and Genetic Makeup of Domestic Horses
published pages: 423-434, ISSN: 0016-6731, DOI: 10.1534/genetics.116.194860
Genetics 204/2 2019-06-13

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