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YAKUT SIGNED

Genomics, epigenomics and transcriptomics of Yakutian horses, a unique domestic breed adapted to life in the Arctic

Total Cost €

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EC-Contrib. €

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Partnership

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 YAKUT project word cloud

Explore the words cloud of the YAKUT project. It provides you a very rough idea of what is the project "YAKUT" about.

despite    adaptations    origin    succeeded    parked    hair    densities    yakutia    exceptional    cold    winter    underlying    gene    regulating    months    transcriptomics    yakutian    responsible    care    breeding    mechanisms    capacities    time    unsurprisingly    spectacular    horses    cutting    reveal    domestic    economy    first    expression    modifications    stables    life    horse    tools    ordm    republic    grazing    seasonal    metabolism    temperatures    cover    receive    deep    history    russian    environment    record    contrast    vegetation    amazing    dna    sound    controversial    federation    natural    northern    reconstruct    sakha    epigenomics    edge    genomic    dataset    extreme    coldest    epigenetic    efforts    breed    found    metabolic    human    genetic    arctic    air    70    yakut    preserve    levels    extensive    heritage    people    ancient    strategies    hemisphere    country    evolutionary    mysterious    genomics    genome    cattle    origins    living    snow   

Project "YAKUT" data sheet

The following table provides information about the project.

Coordinator		 KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Denmark [DK]
 Total cost 200˙194 €
 EC max contribution 200˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-15   to  2017-09-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 200˙194.00

Map

 Project objective

Yakutia (Sakha Republic, Russian Federation) is the coldest country in the Northern hemisphere with winter record temperatures as low as -70ºC. Despite such extreme conditions, the Yakut people succeeded in developing an economy based on extensive horse and cattle breeding. In contrast to cattle, that are parked in stables at winter, horses do not receive much human care, living all the year in the open air and grazing on vegetation that is under deep snow cover for 7-8 months. Unsurprisingly, Yakutian horses developed amazing adaptations to life in the cold Arctic, including exceptional hair densities for domestic horses and spectacular capacities for regulating their metabolism. The origin of Yakutian horses is controversial. In the YAKUT project, we will use cutting-edge genomic tools including genomics, transcriptomics and epigenomics, together with state-of-the-art methods in ancient DNA research, to reconstruct the evolutionary history of Yakutian horses from its mysterious origins to its adaptation to life in the Arctic. Our extensive genomic dataset will provide essential information to foster efforts for developing sound management strategies to preserve this unique genetic heritage. Following seasonal gene expression levels and associated epigenetic modifications at the whole genome scale, we will reveal for the first time the mechanisms responsible for the exceptional metabolic adaptations found in Yakutian horses. Overall, the YAKUT project aims at understanding the process of natural selection underlying the adaptation of a domestic breed to life in an extreme environment.

 Publications

year authors and title journal last update
List of publications.
2016 Michela Leonardi, Pablo Librado, Clio Der Sarkissian, Mikkel Schubert, Ahmed H. Alfarhan, Saleh A. Alquraishi, Khaled A. S. Al-Rasheid, Cristina Gamba, Eske Willerslev, Ludovic Orlando
Evolutionary Patterns and Processes: Lessons from Ancient DNA
published pages: syw059, ISSN: 1063-5157, DOI: 10.1093/sysbio/syw059 		Systematic Biology 2019-06-13
2016 P. Librado, A. Fages, C. Gaunitz, M. Leonardi, S. Wagner, N. Khan, K. Hanghoj, S. A. Alquraishi, A. H. Alfarhan, K. A. Al-Rasheid, C. Der Sarkissian, M. Schubert, L. Orlando
The Evolutionary Origin and Genetic Makeup of Domestic Horses
published pages: 423-434, ISSN: 0016-6731, DOI: 10.1534/genetics.116.194860 		Genetics 204/2 2019-06-13

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