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YIELDFACTOR

Using SP1 to control plastid development and yield in cereals

Total Cost €

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EC-Contrib. €

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Partnership

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 YIELDFACTOR project word cloud

Explore the words cloud of the YIELDFACTOR project. It provides you a very rough idea of what is the project "YIELDFACTOR" about.

brachypodium    rates    sensitive    2012    outer    plant    survival    thoroughly    etiolation    sp1    traits    transgenic    science    staygreen    yield    manipulating    unpublished    importing    toc    translocon    combination    correlated    significantly    membrane    function    model    delaying    inefficient    delayed    strength    responsible    arabidopsis    grain    shown    interconversion    phenotype    degradation    weight    cytosolic    plastids    regulate    generate    expression    sativa    differentiation    seed    e3    cereals    transformants    skills    plastid    cereal    amyloplast    leaf    content    time    host    senescence    starch    oryza    plants    achieves    found    proteasome    encoded    distachyon    338    discovery    lab    stress    agriculture    proteins    regulates    de    resistance    decreasing    components    expertise    germination    655    modifying    suggests    beneficial    mutants    linked    ups    first    manipulated    versatile    rice    data    ubiquitin    types    suggest    null    recently    ligase    levels    complementarity    nucleus    chloroplast    multiple    26s   

Project "YIELDFACTOR" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Organization address
address: WELLINGTON SQUARE UNIVERSITY OFFICES
city: OXFORD
postcode: OX1 2JD
website: www.ox.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://users.ox.ac.uk/
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-07   to  2018-03-06

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) coordinator 195˙454.00

Map

 Project objective

Recently, the host lab found that a novel ubiquitin E3 ligase, SP1, regulates the translocon of the outer chloroplast membrane (TOC), which is responsible for importing nucleus-encoded proteins into plastids. SP1 achieves this by promoting the degradation TOC components by the cytosolic 26S proteasome. This is the first time the ubiquitin proteasome system (UPS) has been shown to directly regulate plastid development and function. By increasing or decreasing SP1 levels in transgenic Arabidopsis plants, multiple effects of SP1 were observed; e.g., inefficient de-etiolation leading to low survival rates and delayed leaf senescence in sp1 null mutants (Science 2012, 338:655-9). Also, sp1 mutants are significantly more sensitive to stress (unpublished). These data suggest that SP1 is important for the differentiation and interconversion of different plastid types, and all of the effects are highly correlated with plant growth and yield. Thus, discovery of SP1 strongly suggests potential applications in agriculture, such as delaying leaf senescence to produce a staygreen phenotype, or controlling amyloplast development during grain development, by modifying SP1 expression. This project will investigate the function of SP1 in cereals, and assess the potential of SP1 for manipulating plastids to improve cereal yield. I will generate transgenic plants with manipulated SP1 expression in Brachypodium distachyon (a versatile cereal model) and Oryza sativa (rice). I will study the development of plastids in the transformants, and assess the transformants for beneficial effects on yield parameters, such as starch content, seed weight, germination, de-etiolation, leaf senescence and stress resistance. At the end, I will have thoroughly assessed the potential use of SP1 for manipulating cereal traits linked to yield. A major strength of the proposal is the complementarity of my expertise with that of the host. Our unique combination of skills will ensure success of the project.

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The information about "YIELDFACTOR" are provided by the European Opendata Portal: CORDIS opendata.

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