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Versatile optomechANical GRaphene Device for bio-tissue engineering

Total Cost €


EC-Contrib. €






 VANGUARD project word cloud

Explore the words cloud of the VANGUARD project. It provides you a very rough idea of what is the project "VANGUARD" about.

first    health    microscopy    thanks    scalable    desired    organs    flat    vitro    regeneration    roughness    substrate    fabricate    partly    consuming    membrane    oxide    damaged    care    model    consists    vivo    spatial    attachment    damage    human    fabrication    combination    functions    manner    tissue    flexibility    initially    asperities    cells    designing    maxima    analogously    local    reconfigurable    rough    versatile    shapes    material    costly    detected    hierarchical    scaffolds    vanguard    graphene    mimic    single    accounts    surfaces    onto    deformation    components    restoring    hardware    strength    plan    laser    caused    made    opto    special    business    easily    surgical    dynamically    device    injury    atomic    techniques    dynamical    entire    commercialization    light    porous    successful    force    idea    deposited    tissues    layer    pixelated    feasibility    consisting    software    emerged    realize    grafting    contact    extremely    mechanical    modulator    natural    efficient    engineering    fabricating    expanding    time    profile    fold    adhesion    utilize    biological    surface    prototype    deform    building    seeding    scaffold    repair    organ   

Project "VANGUARD" data sheet

The following table provides information about the project.


Organization address
city: ROMA
postcode: 185

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-04-01   to  2016-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Tissue and organ failure, caused by injury or other type of damage, accounts for a large part of the health care costs in EU and U.S. Current surgical or grafting procedures are only partly successful in restoring the functions of the damaged tissues.Tissue Engineering has emerged as a rapidly expanding field for repair and regeneration of damaged tissue and organs.This involves the seeding and attachment of human cells onto a scaffold through in-vitro, or a combination of in-vitro and in-vivo. Existing scaffold fabrication techniques are time consuming and costly. We plan to take the first steps towards the commercialization of a novel system to fabricate tissue scaffolds made of Graphene Oxide (GO) in an extremely dynamical and efficient manner. The prototype consists of opto-mechanical and laser components that will be used to dynamically deform the initially flat surface consisting of a single layer of GO deposited over a porous membrane. Specifically, we will utilize a Spatial Light Modulator laser and a novel software application in order to realize a pixelated surface with the desired profile. The spatial deformation will be controlled and detected with the use of Atomic Force Microscopy. Special shapes of the asperities, i.e. local surface maxima of a rough surface, enhance adhesion over the entire surface when in contact with a biological material. Analogously to known natural surfaces with hierarchical roughness, we aim to mimic this kind of effects by using Graphene thanks to its high strength and flexibility. All in all, the goal of VANGuaRD is two-fold: (1) to establish the technical feasibility of our idea by designing and building a highly versatile prototype device that includes both hardware and software components for fabricating easily reconfigurable GO-based scaffolds using only a single substrate. (2) to establish the commercialization potential of such system by means of designing a viable and scalable business model.


year authors and title journal last update
List of publications.
2016 Maria Chiara Braidotti, Silvia Gentilini, Claudio Conti
Gamow vectors explain the shock profile
published pages: 21963, ISSN: 1094-4087, DOI: 10.1364/OE.24.021963
Optics Express 24/19 2019-07-24
2016 Renato Fastampa, Mauro Missori, Maria Chiara Braidotti, Claudio Conti, Maria Aurora Vincenti, Rosa Maria Montereali
Temperature behavior of optical absorption bands in colored LiF crystals
published pages: 74-75, ISSN: 2211-3797, DOI: 10.1016/j.rinp.2016.01.013
Results in Physics 6 2019-07-24
2016 Massimiliano Papi, Valentina Palmieri, Francesca Bugli, Marco De Spirito, Maurizio Sanguinetti, Carlotta Ciancico, Maria Chiara Braidotti, Silvia Gentilini, Luca Angelani, Claudio Conti
Biomimetic antimicrobial cloak by graphene-oxide agar hydrogel
published pages: 12, ISSN: 2045-2322, DOI: 10.1038/s4159801600107
Scientific Reports 6 2019-07-24
2015 Silvia Gentilini, Maria Chiara Braidotti, Giulia Marcucci, Eugenio DelRe, Claudio Conti
Physical realization of the Glauber quantum oscillator
published pages: 15816, ISSN: 2045-2322, DOI: 10.1038/srep15816
Scientific Reports 5 2019-07-24
2016 Maria Chiara Braidotti, Silvia Gentilini, Adam Fleming, Michiel C. Samuels, Andrea Di Falco, Claudio Conti
Optothermal nonlinearity of silica aerogel
published pages: 41104, ISSN: 0003-6951, DOI: 10.1063/1.4959240
Applied Physics Letters 109/4 2019-07-24

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