Explore the words cloud of the SEXSEA project. It provides you a very rough idea of what is the project "SEXSEA" about.
The following table provides information about the project.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
|Coordinator Country||France [FR]|
|Total cost||1˙498˙694 €|
|EC max contribution||1˙498˙694 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2015-06-01 to 2020-05-31|
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|1||CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS||FR (PARIS)||coordinator||1˙498˙694.00|
Sexual reproduction is an extraordinarily widespread phenomenon that assures the production of new genetic combinations in nearly all eukaryotic lineages. Although the core mechanisms of sexual reproduction (meiosis and syngamy) are highly conserved, the control mechanisms that determine whether an individual is male or female are remarkably labile across eukaryotes. In genetically controlled sexual systems, gender is determined by sex chromosomes, which have emerged independently and repeatedly during evolution. Sex chromosomes have been studied in only a handful of classical model organism, and empirical knowledge on the origin and evolution of the sexes is still surprisingly incomplete. The goal of our project is to exploit the remarkable richness of sexual characteristics of the brown algae to gain novel insights into the functional and evolutionary interactions between the sex chromosomes and key eukaryotic reproductive and life cycle features. First, we will use the model brown alga Ectocarpus to reveal the fundamental genetic mechanisms by which sex chromosomes control reproductive and life cycle traits of broad importance to all eukaryotes, including sex determination and asexual reproduction through parthenogenesis but also the control of gamete size and the regulation of developmental switches during the life cycle. Secondly, we will employ a combination of experimental and computational approaches on selected brown algal species exhibiting a range of reproductive and life cycle features to understand the long term evolutionary consequences of the variations in these traits to the structure of their sex chromosomes, in a phylogenetic context. These analyses will not only reveal fundamental forces that shape sex chromosome evolution in the scope of the tree of life, but will also uncover the mechanisms underlying important evolutionary transitions between major reproductive and life cycle modes and shed new light on the origin and evolution of the sexes.
|year||authors and title||journal||last update|
Nicolas Macaisne, Fuli Liu, Delphine Scornet, Akira F. Peters, Agnieszka Lipinska, Marie-Mathilde Perrineau, Antoine Henry, Martina Strittmatter, Susana M. Coelho, J. Mark Cock
The Ectocarpus IMMEDIATE UPRIGHT gene encodes a member of a novel family of cysteine-rich proteins that have an unusual distribution across the eukaryotes
published pages: dev.141523, ISSN: 0950-1991, DOI: 10.1242/dev.141523
J. Mark Cock, Fuli Liu, Delin Duan, Simon Bourdareau, Agnieszka P. Lipinska, Susana M. Coelho, James E. Tarver
Rapid Evolution of microRNA Loci in the Brown Algae
published pages: 740-749, ISSN: 1759-6653, DOI: 10.1093/gbe/evx038
|Genome Biology and Evolution 9/3||2019-05-29|
Komlan Avia, Agnieszka Lipinska, Laure Mignerot, Alejandro Montecinos, Mahwash Jamy, Sophia Ahmed, Myriam Valero, Akira Peters, J. Cock, Denis Roze, Susana Coelho
Genetic Diversity in the UV Sex Chromosomes of the Brown Alga Ectocarpus
published pages: 286, ISSN: 2073-4425, DOI: 10.3390/genes9060286
Laure Mignerot, Susana M. Coelho
The origin and evolution of the sexes: Novel insights from a distant eukaryotic linage
published pages: 252-257, ISSN: 1631-0691, DOI: 10.1016/j.crvi.2016.04.012
|Comptes Rendus Biologies 339/7-8||2019-05-29|
Komlan Avia, Susana M. Coelho, Gabriel J. Montecinos, Alexandre Cormier, Fiona Lerck, StÃ©phane Mauger, Sylvain Faugeron, Myriam Valero, J. Mark Cock, Pierre Boudry
High-density genetic map and identification of QTLs for responses to temperature and salinity stresses in the model brown alga Ectocarpus
published pages: 43241, ISSN: 2045-2322, DOI: 10.1038/srep43241
|Scientific Reports 7||2019-05-29|
RÃ©my Luthringer, Agnieszka P. Lipinska, Denis Roze, Alexandre Cormier, Nicolas Macaisne, Akira F. Peters, J. Mark Cock, Susana M. Coelho
The Pseudoautosomal Regions of the U/V Sex Chromosomes of the Brown Alga Ectocarpus Exhibit Unusual Features
published pages: 2973-2985, ISSN: 0737-4038, DOI: 10.1093/molbev/msv173
|Molecular Biology and Evolution 32/11||2019-05-29|
Olivier Godfroy, Toshiki Uji, Chikako Nagasato, Agnieszka P Lipinska, Delphine Scornet, Akira F. Peters, Komlan Avia, Sebastien Colin, Mignerot Laure, Taizo Motomura, J. Mark Cock, Susana M. Coelho
DISTAG/TBCCd1 Is Required for Basal Cell Fate Determination in Ectocarpus
published pages: tpc.00440.2017, ISSN: 1040-4651, DOI: 10.1105/tpc.17.00440
|The Plant Cell||2019-05-29|
Juliet Brodie, Cheong Xin Chan, Olivier De Clerck, J. Mark Cock, Susana M. Coelho, Claire Gachon, Arthur R. Grossman, Thomas Mock, John A. Raven, Alison G. Smith, Hwan Su Yoon, Debashish Bhattacharya
The Algal Revolution
published pages: 726-738, ISSN: 1360-1385, DOI: 10.1016/j.tplants.2017.05.005
|Trends in Plant Science 22/8||2019-05-29|
Alexandre Cormier, Komlan Avia, Lieven Sterck, Thomas Derrien, Valentin Wucher, Gwendoline Andres, Misharl Monsoor, Olivier Godfroy, Agnieszka Lipinska, Marie-Mathilde Perrineau, Yves Van De Peer, Christophe Hitte, Erwan Corre, Susana M. Coelho, J. Mark Cock
Re-annotation, improved large-scale assembly and establishment of a catalogue of noncoding loci for the genome of the model brown alga Ectocarpus
published pages: , ISSN: 0028-646X, DOI: 10.1111/nph.14321
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