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ADVANTAGE SIGNED

ADvanced Validation of A Novel TB Active disease diagnostic to address Global unmet needs: a European consortium approach

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 ADVANTAGE project word cloud

Explore the words cloud of the ADVANTAGE project. It provides you a very rough idea of what is the project "ADVANTAGE" about.

supply    demonstrated    eight    microfluidic    costly    reagents    despite    efforts    profile    bn    active    poorly    reduce    ground    creation    healthcare    risks    regulatory    samples    tb    laboratory    point    million    successfully    disruptive    analytes    structured    reader    diagnostic    private    breaking    uk    panel    companies    packages    transitioning    hold    performance    instrument    confirm    clear    validation    proven    biomarker    human    poc    commercial    mediated    burden    serum    tuberculosis    proof    biomarkers    security    meet    plus    care    company    clinical    biosensia    400    massive    yield    improvements    practises    elusive    deaths    investment    patient    diagnostics    assay    analytical    advantage    validated    global    unmet    proteinlogic    variety    standards    cartridge    summary    stimulate    slow    jobs    selective    1    time    rapid    eradicate    globally    platform    accounting    commercialisation    cell    ing    successful    protein   

Project "ADVANTAGE" data sheet

The following table provides information about the project.

Coordinator		 PROTEINLOGIC LIMITED 

Organization address
address: SHAKESPEARE HOUSE 42 NEWMARKET ROAD
city: CAMBRIDGE CAMBRIDGESHIRE
postcode: CB5 8EP
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country United Kingdom [UK]
 Project website http://www.proteinlogic.com
 Total cost 3˙893˙307 €
 EC max contribution 3˙583˙396 € (92%)
 Programme 1. H2020-EU.3.1. (SOCIETAL CHALLENGES - Health, demographic change and well-being)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-2-2014
 Funding Scheme SME-2
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2018-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PROTEINLOGIC LIMITED UK (CAMBRIDGE CAMBRIDGESHIRE) coordinator 2˙921˙750.00
2    BIOSENSIA LIMITED IE (DUBLIN) participant 661˙646.00

Map

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 Project objective

Tuberculosis (TB) remains an EU and global healthcare priority resulting in over 1.4 million deaths each year. Despite this and efforts to reduce TB by the EU commission, the WHO and others, a simple, rapid, diagnostic test for active tuberculosis (TB) remains elusive. Current diagnostic procedures, while accounting for over $1 bn globally, are poorly selective for active TB, hold risks for healthcare personnel, are slow to yield results and costly.

The large potential and high unmet need provide a clear target for commercialisation of a point-of-care (POC) test. Using over 400 clinical samples, ProteinLogic (a UK based diagnostics company) have demonstrated proof of concept for a ground-breaking approach using a panel of protein biomarkers on human serum samples that profile the cell mediated patient response to TB.

The objectives of the eight structured work packages within this three year project are to build on the validation of the biomarker TB panel transitioning from a laboratory assay to Biosensia’s novel microfluidic POC platform that has already been successfully proven with a variety of human analytes. Reagents will be developed as part of this project to ensure reduced costs and security of commercial supply. A unique instrument reader plus TB cartridge-based product will be developed to meet EU regulatory standards. The products will be validated in order to confirm analytical and clinical performance, and to provide evidence of major time, cost & performance improvements compared to current TB testing practises. Successful commercialisation will lead to the creation of over 30 new jobs and will stimulate further private investment in each of the companies.

In summary, ADVANTAGE has the potential to deliver a disruptive POC TB diagnostic test that can help eradicate the massive TB burden not only in EU but also globally.

 Deliverables

List of deliverables.
Clone scale Websites, patent fillings, videos etc. 2019-05-30 13:18:55

Take a look to the deliverables list in detail:  detailed list of ADVANTAGE deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "ADVANTAGE" project.

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Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

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The information about "ADVANTAGE" are provided by the European Opendata Portal: CORDIS opendata.

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ADVANTAGE (2015)

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