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Development of a digital diagnostics rapid Lung Maturity Test (LMT) for premature infants, to assist neonatologists in the diagnosis of Respiratory Distress Syndrome at birth

Total Cost €


EC-Contrib. €






 SIME-LMT project word cloud

Explore the words cloud of the SIME-LMT project. It provides you a very rough idea of what is the project "SIME-LMT" about.

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Project "SIME-LMT" data sheet

The following table provides information about the project.


Organization address
address: Stevenage Bioscience Catalyst, Gunnel Wood Road
postcode: SG1 2FX
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 3˙417˙674 €
 EC max contribution 2˙864˙455 € (84%)
 Programme 1. H2020-EU.3.1. (SOCIETAL CHALLENGES - Health, demographic change and well-being)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-2-2014
 Funding Scheme SME-2
 Starting year 2015
 Duration (year-month-day) from 2015-04-01   to  2017-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SIME DIAGNOSTICS LIMITED UK (STEVENAGE) coordinator 2˙864˙455.00


 Project objective

SIME LMT will develop a simple digital, software and cloud-based diagnostic test to analyse very small samples of bodily fluid at point of care that predicts the risk of an infant developing Respiratory Distress Syndrome (RDS) within 10 minutes of birth. The platform will offer neonatologists more control through greater accuracy and faster results so they can deliver optimal patient care and improve clinical outcomes. Such technology has not been deployed before in healthcare diagnostics because of the complexity of the required knowledge and expertise in the field of chemometrics. RDS can only be prevented by a quick diagnosis of lung maturity and treatment at birth.

We have developed a working prototype test that measures within 95% of the established laboratory and chemistry validation methods. We are currently refining the method in a pre-clinical test which will provide test validation data and demonstrate that the test improves clinical outcomes and enables change in clinical practice from the current treatment standard to a preventative treatment protocol which reduces RDS i.e. generating Level 4 – Level 1 evidence.

Our initial target market is the NICUs: 2000 in the US and 1,400 in the EU, where there is an estimated market of 916,000 tests and a revenue potential of approx. €375m per annum. SIME Diagnostics also has the potential to reduce neonatal intensive care treatment including mechanical ventilation by 60%, less time on oxygen and hospital stay by 10 days. The overall savings opportunity has been estimated to be more than €3.4bn total, and €1.5m per 100 cases representing a cost savings and profit making opportunity for healthcare providers worldwide. The project is well aligned with our business growth strategy which is aimed at growing the business through digitising biological information, driving innovation in life sciences and healthcare. Attaining level 1 clinical evidence will increase company valuation to >€60m.


List of deliverables.
Approved publication Documents, reports 2019-05-30 11:42:35
Project Specific Website Other 2019-05-30 11:42:34
Production tooling, sample batch (spectrometers) Demonstrators, pilots, prototypes 2019-05-30 11:42:35

Take a look to the deliverables list in detail:  detailed list of SIME-LMT deliverables.

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The information about "SIME-LMT" are provided by the European Opendata Portal: CORDIS opendata.

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