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SIME-LMT

Development of a digital diagnostics rapid Lung Maturity Test (LMT) for premature infants, to assist neonatologists in the diagnosis of Respiratory Distress Syndrome at birth

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

SIME-LMT project word cloud

Explore the words cloud of the SIME-LMT project. It provides you a very rough idea of what is the project "SIME-LMT" about.

representing profit optimal data generating standard rds digital refining driving distress quick 2000 bodily infant biological small chemometrics 60 diagnostics digitising 60m tests neonatal prevented business point prototype providers revenue patient savings 5m accuracy days strategy cloud intensive care maturity clinical diagnosis opportunity sime annum stay 4bn life birth 400 375m software laboratory 916 worldwide market syndrome ventilation chemistry initial predicts risk respiratory gt mechanical complexity neonatologists samples reduce healthcare 95 preventative faster valuation outcomes reduces treatment innovation improves fluid validation nicus diagnostic sciences protocol expertise total oxygen attaining lung time aligned approx platform hospital company lmt minutes

Project "SIME-LMT" data sheet

The following table provides information about the project.

Coordinator	SIME DIAGNOSTICS LIMITED Organization address address: Stevenage Bioscience Catalyst, Gunnel Wood Road city: STEVENAGE postcode: SG1 2FX website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.simelmt.com
Total cost	3˙417˙674 €
EC max contribution	2˙864˙455 € (84%)
Programme	1. H2020-EU.3.1. (SOCIETAL CHALLENGES - Health, demographic change and well-being) 2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
Code Call	H2020-SMEINST-2-2014
Funding Scheme	SME-2
Starting year	2015
Duration (year-month-day)	from 2015-04-01 to 2017-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SIME DIAGNOSTICS LIMITED SIME DIAGNOSTICS LIMITED Organization address address: Stevenage Bioscience Catalyst, Gunnel Wood Road city: STEVENAGE postcode: SG1 2FX website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (STEVENAGE)	coordinator	2˙864˙455.00

Map

Project objective

SIME LMT will develop a simple digital, software and cloud-based diagnostic test to analyse very small samples of bodily fluid at point of care that predicts the risk of an infant developing Respiratory Distress Syndrome (RDS) within 10 minutes of birth. The platform will offer neonatologists more control through greater accuracy and faster results so they can deliver optimal patient care and improve clinical outcomes. Such technology has not been deployed before in healthcare diagnostics because of the complexity of the required knowledge and expertise in the field of chemometrics. RDS can only be prevented by a quick diagnosis of lung maturity and treatment at birth.

We have developed a working prototype test that measures within 95% of the established laboratory and chemistry validation methods. We are currently refining the method in a pre-clinical test which will provide test validation data and demonstrate that the test improves clinical outcomes and enables change in clinical practice from the current treatment standard to a preventative treatment protocol which reduces RDS i.e. generating Level 4 – Level 1 evidence.

Our initial target market is the NICUs: 2000 in the US and 1,400 in the EU, where there is an estimated market of 916,000 tests and a revenue potential of approx. €375m per annum. SIME Diagnostics also has the potential to reduce neonatal intensive care treatment including mechanical ventilation by 60%, less time on oxygen and hospital stay by 10 days. The overall savings opportunity has been estimated to be more than €3.4bn total, and €1.5m per 100 cases representing a cost savings and profit making opportunity for healthcare providers worldwide. The project is well aligned with our business growth strategy which is aimed at growing the business through digitising biological information, driving innovation in life sciences and healthcare. Attaining level 1 clinical evidence will increase company valuation to >€60m.

Deliverables

List of deliverables.
Approved publication	Documents, reports	2019-05-30 11:42:35
Project Specific Website	Other	2019-05-30 11:42:34
Production tooling, sample batch (spectrometers)	Demonstrators, pilots, prototypes	2019-05-30 11:42:35

Take a look to the deliverables list in detail: detailed list of SIME-LMT deliverables.

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The information about "SIME-LMT" are provided by the European Opendata Portal: CORDIS opendata.

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SIME-LMT (2015)

Development of a digital diagnostics rapid Lung Maturity Test (LMT) for premature infants, to assist neonatologists in the diagnosis of Respiratory Distress Syndrome at birth