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In vivo histology using femtosecond laser multiphoton tomograph for the early diagnosis of skin cancer and corneal diseases while simultaneously reducing Europe’s health care costs

Total Cost €


EC-Contrib. €






Project "LASER-HISTO" data sheet

The following table provides information about the project.


Organization address
address: Nerkewitzer Strasse 18
postcode: 7778

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website
 Total cost 2˙477˙500 €
 EC max contribution 2˙477˙500 € (100%)
 Programme 1. H2020-EU.3.1. (SOCIETAL CHALLENGES - Health, demographic change and well-being)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JENLAB GMBH DE (NEUENGOENA) coordinator 2˙477˙500.00


 Project objective

1.3 million – this is the sad number of Europeans dying each year by cancer. JenLab, high-tech company from Germany, has therefore developed an innovative novel diagnostic medical device (TRL 7) based on femtosecond laser radiation for immediate, non-invasive early diagnosis of cancer, particularly skin cancer, within seconds and with ultra-high resolution depicting even subcellular level. This is also true for early detection of ophthalmic diseases which constitute a major burden for Europe’s society –knowing that one European in every 30 is expected to experience sight loss. In addition to intratissue cell imaging, JenLab’s technology is able to measure metabolic processes giving information about diseases even before they become visible – increasing therapy success by early detection and continuous monitoring. Moreover, the technology is applicable for imaging each tissue without labelling but using endogenous biomarkers. Outcome of the business innovation project is an miniaturised, certified and by clinical study validated ultracompact, flexible, fast multiphoton tomograph for dermatologists and ophthalmologists, representing an European market potential of EUR 11.4 bn. Particularly by its quick and reliable (using 4 different modes of diagnostic) way of diagnosis it meets user needs while simultaneously reducing Europe’s continuously growing health care costs. The business project is in line with JenLab’s philosophy of saving lifes and of facilitate healing as well as it is in line with JenLab’s strategy of developing and producing novel solutions for early diagnosis of life threatening and/or serious diseases.


List of deliverables.
CE Mark Documents, reports 2019-05-31 10:54:58
International Product Registrations Documents, reports 2019-05-31 10:54:59
Website Websites, patent fillings, videos etc. 2019-05-31 10:54:51

Take a look to the deliverables list in detail:  detailed list of LASER-HISTO deliverables.


year authors and title journal last update
List of publications.
2017 K. König
JenLab offers a new quality check for corneal transplantation
published pages: , ISSN: , DOI:
TheNewEconomy 2019-05-08
2018 K. König
Multiphoton tomography (MPT)
published pages: , ISSN: , DOI:
2018 M. Weinigel, HG Breunig, K. König
Clinical multimodal CARS imaging
published pages: , ISSN: , DOI:
2018 A. Batista, HG Breunig, A. König, A. Schindele, T. Hager, B. Seitz, AM Morgado, K. König
Assessment of human corneas prior to transplantation using high-resolution two-photon imaging
published pages: , ISSN: 1552-5783, DOI:
Investigative Ophthalmology & Visual Science 2019-05-08
2017 H.G. Breunig, B. Sauer, A. Batista, K. König
Rapid vertical tissue imaging with clinical multiphoton tomography
published pages: , ISSN: , DOI:
2018 A. Batista, HG Breunig, C. Donitzky, K. König
Two-photon microscopy and fluorescence lifetime imaging of the cornea.
published pages: , ISSN: , DOI:
2018 Andreas Schindele, Hans Georg Breunig, Karsten König
Multiphoton Tomography for in Vivo Skin Age Determination
published pages: 56-59, ISSN: 1863-1460, DOI: 10.1002/opph.201800009
Optik & Photonik 13/2 2019-05-08
2018 A. Batista, A. Uchugonova, HG. Breunig, K. König
Towards in vivo breast skin characterization using multiphoton tomography
published pages: , ISSN: , DOI:
2018 Ana Batista, Hans Georg Breunig, Aisada König, Andreas Schindele, Tobias Hager, Berthold Seitz, Karsten König
High-resolution, label-free two-photon imaging of diseased human corneas
published pages: 1, ISSN: 1083-3668, DOI: 10.1117/1.JBO.23.3.036002
Journal of Biomedical Optics 23/03 2019-05-08
2018 K. König
Multiphoton Microscopy and Fluorescence Lifetime Imaging
published pages: , ISSN: , DOI:
2017 K. König, A. Batista, B. Seitz
Multiphoton tomography of the human eye
published pages: , ISSN: , DOI:
2018 Ana Batista, Hans G. Breunig, Aisada König, António M. Morgado, Karsten König
Assessment of the metabolism and morphology of the porcine cornea, lens and retina by 2-photon imaging
published pages: e201700324, ISSN: 1864-063X, DOI: 10.1002/jbio.201700324
Journal of Biophotonics 11/7 2019-05-08
2017 A. Batista, H.G. Breunig, A. Uchugonova, K. König
In vivo multiphoton imaging of the eyelid skin
published pages: , ISSN: , DOI:
2018 K. König. A. Batista, T. Hager, B. Seitz
Multiphoton tomography of the human eye
published pages: , ISSN: , DOI:

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The information about "LASER-HISTO" are provided by the European Opendata Portal: CORDIS opendata.

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