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EMBRYOandLATERHEALTH SIGNED

Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective

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Project "EMBRYOandLATERHEALTH" data sheet

The following table provides information about the project.

Coordinator
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM 

Organization address
address: DR MOLEWATERPLEIN 40
city: ROTTERDAM
postcode: 3015 GD
website: www.erasmusmc.nl

contact info
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name: n.a.
surname: n.a.
function: n.a.
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 Coordinator Country Netherlands [NL]
 Project website http://www.generationr.nl/next
 Total cost 1˙969˙586 €
 EC max contribution 1˙969˙586 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-CoG
 Funding Scheme ERC-COG
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) coordinator 1˙969˙586.00

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 Project objective

Children born preterm or with a small size at birth have increased risks of cardiovascular disease and type 2 diabetes in adulthood. These intriguing associations strongly suggest that common diseases have at least part of their origins in early fetal life. From both an etiological and preventive perspective, it is important to disentangle the early fetal critical periods and causal pathways. An accumulating body of evidence suggests that early pregnancy, or even the preconception period, may influence the risk of cardiovascular and metabolic disease throughout the lifecourse. The main hypothesis for this project is that adverse exposures before or very early in pregnancy induce embryonic and placental developmental adaptations, which permanently affect cardiovascular and metabolic development and predispose individuals to both adverse outcomes at birth and cardiovascular and metabolic dysfunction and diseases in later life. I will use an integrated epidemiological, molecular and clinical full lifecourse approach from preconception to adulthood embedded in three population-based cohort studies. Innovative element are: 1) focus on developmental adaptations during the embryonic phase and early placentation assessed by advanced imaging studies at 6, 8, 10 and 12 weeks of gestation; (2) detailed cardiovascular and metabolic studies in infancy and late childhood, including 3T MRI of the heart, aorta, liver and abdomen, metabolomics analyses; and (3) genome-wide DNA-methylation studies to identify specific DNA-methylation changes related to preconception or early pregnancy exposures, which persist in late childhood and adulthood and are associated with cardiovascular and metabolic outcomes in later life. With these approaches, this project will provide unique and important new perspectives into the earliest origins of cardiovascular disease and type 2 diabetes and will ultimately contribute to development of preventive strategies focused on future parents and children.

 Publications

year authors and title journal last update
List of publications.
2017 Jolien Rijlaarsdam, Marinus H. van IJzendoorn, Frank C. Verhulst, Vincent W. V. Jaddoe, Janine F. Felix, Henning Tiemeier, Marian J. Bakermans-Kranenburg
Prenatal stress exposure, oxytocin receptor gene ( OXTR ) methylation, and child autistic traits: The moderating role of OXTR rs53576 genotype
published pages: 430-438, ISSN: 1939-3806, DOI: 10.1002/aur.1681
Autism Research 10/3 2019-06-07
2018 Mònica Guxens, Małgorzata J. Lubczyńska, Ryan L. Muetzel, Albert Dalmau-Bueno, Vincent W.V. Jaddoe, Gerard Hoek, Aad van der Lugt, Frank C. Verhulst, Tonya White, Bert Brunekreef, Henning Tiemeier, Hanan El Marroun
Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children
published pages: , ISSN: 0006-3223, DOI: 10.1016/j.biopsych.2018.01.016
Biological Psychiatry 2019-06-07
2018 Elise M. Philips, Vincent W.V. Jaddoe, Alexandros G. Asimakopoulos, Kurunthachalam Kannan, Eric A.P. Steegers, Susana Santos, Leonardo Trasande
Bisphenol and phthalate concentrations and its determinants among pregnant women in a population-based cohort in the Netherlands, 2004–5
published pages: 562-572, ISSN: 0013-9351, DOI: 10.1016/j.envres.2017.11.051
Environmental Research 161 2019-06-07
2016 Susana Santos, Romy Gaillard, Andreia Oliveira, Henrique Barros, Marieke Abrahamse-Berkeveld, Eline M. van der Beek, Albert Hofman, Vincent W. V. Jaddoe
Associations of Infant Subcutaneous Fat Mass with Total and Abdominal Fat Mass at School-Age: The Generation R Study
published pages: 511-520, ISSN: 0269-5022, DOI: 10.1111/ppe.12307
Paediatric and Perinatal Epidemiology 30/5 2019-06-07
2016 Ardashel Latsuzbaia, Vincent W. V. Jaddoe, Albert Hofman, Oscar H. Franco, Janine F. Felix
Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study
published pages: 2185-2192, ISSN: 0022-2275, DOI: 10.1194/jlr.P066902
Journal of Lipid Research 57/12 2019-06-07
2016 Marjolein N. Kooijman, Claudia J. Kruithof, Cornelia M. van Duijn, Liesbeth Duijts, Oscar H. Franco, Marinus H. van IJzendoorn, Johan C. de Jongste, Caroline C. W. Klaver, Aad van der Lugt, Johan P. Mackenbach, Henriëtte A. Moll, Robin P. Peeters, Hein Raat, Edmond H. H. M. Rings, Fernando Rivadeneira, Marc P. van der Schroeff, Eric A. P. Steegers, Henning Tiemeier, André G. Uitterlinden, Frank C. Verhulst, Eppo Wolvius, Janine F. Felix, Vincent W. V. Jaddoe
The Generation R Study: design and cohort update 2017
published pages: 1243-1264, ISSN: 0393-2990, DOI: 10.1007/s10654-016-0224-9
European Journal of Epidemiology 31/12 2019-06-07
2017 N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe Jr, T Roumeliotaki, A T Hattersley, V Lindi, K Pahkala, K Panoutsopoulou, M Standl, C Flexeder, L Bouchard, E Aagaard Nohr, L Santa Marina, M Kogevinas, H Niinikoski, G Dedoussis, J Heinrich, R M Reynolds, T Lakka, E Zeggini, O T Raitakari, L Chatzi, H M Inskip, M Bustamante, M-F Hivert, M-R Jarvelin, T I A Sørensen, C Pennell, J F Felix, B Jacobsson, F Geller, D M Evans, D A Lawlor
Maternal and fetal genetic contribution to gestational weight gain
published pages: , ISSN: 0307-0565, DOI: 10.1038/ijo.2017.248
International Journal of Obesity 2019-06-07
2016 Aleksandra Jelena Vidakovic, Olta Gishti, Trudy Voortman, Janine F Felix, Michelle A Williams, Albert Hofman, Hans Demmelmair, Berthold Koletzko, Henning Tiemeier, Vincent WV Jaddoe, Romy Gaillard
Maternal plasma PUFA concentrations during pregnancy and childhood adiposity: the Generation R Study
published pages: 1017-1025, ISSN: 0002-9165, DOI: 10.3945/ajcn.115.112847
The American Journal of Clinical Nutrition 103/4 2019-06-07
2017 Despoina Manousaki, Tom Dudding, Simon Haworth, Yi-Hsiang Hsu, Ching-Ti Liu, Carolina Medina-Gómez, Trudy Voortman, Nathalie van der Velde, Håkan Melhus, Cassianne Robinson-Cohen, Diana L. Cousminer, Maria Nethander, Liesbeth Vandenput, Raymond Noordam, Vincenzo Forgetta, Celia M.T. Greenwood, Mary L. Biggs, Bruce M. Psaty, Jerome I. Rotter, Babette S. Zemel, Jonathan A. Mitchell, Bruce Taylor, Mattias Lorentzon, Magnus Karlsson, Vincent V.W. Jaddoe, Henning Tiemeier, Natalia Campos-Obando, Oscar H. Franco, Andre G. Utterlinden, Linda Broer, Natasja M. van Schoor, Annelies C. Ham, M. Arfan Ikram, David Karasik, Renée de Mutsert, Frits R. Rosendaal, Martin den Heijer, Thomas J. Wang, Lars Lind, Eric S. Orwoll, Dennis O. Mook-Kanamori, Karl Michaëlsson, Bryan Kestenbaum, Claes Ohlsson, Dan Mellström, Lisette C.P.G.M. de Groot, Struan F.A. Grant, Douglas P. Kiel, M. Carola Zillikens, Fernando Rivadeneira, Stephen Sawcer, Nicholas J. Timpson, J. Brent Richards
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis
published pages: 227-238, ISSN: 0002-9297, DOI: 10.1016/j.ajhg.2017.06.014
The American Journal of Human Genetics 101/2 2019-06-07
2016 Tim I.M. Korevaar, Daan Nieboer, Peter H.L.T. Bisschop, Mariette Goddijn, Marco Medici, Layal Chaker, Yolanda B. de Rijke, Vincent W.V. Jaddoe, Theo J. Visser, Ewout W. Steyerberg, Henning Tiemeier, Tanja G. Vrijkotte, Robin P. Peeters
Risk factors and a clinical prediction model for low maternal thyroid function during early pregnancy: two population-based prospective cohort studies
published pages: 902-909, ISSN: 0300-0664, DOI: 10.1111/cen.13153
Clinical Endocrinology 85/6 2019-06-07
2016 Kristina Gervin, Christian Magnus Page, Hans Christian D. Aass, Michelle A. Jansen, Heidi Elisabeth Fjeldstad, Bettina Kulle Andreassen, Liesbeth Duijts, Joyce B. van Meurs, Menno C. van Zelm, Vincent W. Jaddoe, Hedvig Nordeng, Gunn Peggy Knudsen, Per Magnus, Wenche Nystad, Anne Cathrine Staff, Janine F. Felix, Robert Lyle
Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition
published pages: 690-698, ISSN: 1559-2294, DOI: 10.1080/15592294.2016.1214782
Epigenetics 11/9 2019-06-07
2018 Herman T. den Dekker, Vincent W. V. Jaddoe, Irwin K. Reiss, Johan C. de Jongste, Liesbeth Duijts
Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
published pages: 183-192, ISSN: 1073-449X, DOI: 10.1164/rccm.201703-0631OC
American Journal of Respiratory and Critical Care Medicine 197/2 2019-06-07
2016 Laura Birks, Maribel Casas, Ana M. Garcia, Jan Alexander, Henrique Barros, Anna Bergström, Jens Peter Bonde, Alex Burdorf, Nathalie Costet, Asta Danileviciute, Merete Eggesbø, Mariana F. Fernández, M. Carmen González-Galarzo, Regina Gražulevičienė, Wojciech Hanke, Vincent Jaddoe, Manolis Kogevinas, Inger Kull, Aitana Lertxundi, Vasiliki Melaki, Anne-Marie Nybo Andersen, Nicolás Olea, Kinga Polanska, Franca Rusconi, Loreto Santa-Marina, Ana Cristina Santos, Tanja Vrijkotte, Daniela Zugna, Mark Nieuwenhuijsen, Sylvaine Cordier, Martine Vrijheid
Occupational Exposure to Endocrine-Disrupting Chemicals and Birth Weight and Length of Gestation: A European Meta-Analysis
published pages: , ISSN: 0091-6765, DOI: 10.1289/EHP208
Environmental Health Perspectives 124/11 2019-06-07
2017 Laura Benschop, Sarah Schalekamp–Timmermans, Jeanine E. Roeters van Lennep, Vincent W. V. Jaddoe, Tien Yin Wong, Carol Y. Cheung, Eric A. P. Steegers, M. Kamran Ikram
Gestational hypertensive disorders and retinal microvasculature: the Generation R Study
published pages: , ISSN: 1741-7015, DOI: 10.1186/s12916-017-0917-2
BMC Medicine 15/1 2019-06-07
2017 Gemma C Sharp, Lucas A Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W Holloway, Akram Ghantous, Simon K Merid, Kelly M Bakulski, Leanne K Küpers, Hongmei Zhang, Rebecca C Richmond, Christian M Page, Liesbeth Duijts, Rolv T Lie, Phillip E Melton, Judith M Vonk, Ellen A Nohr, ClarLynda Williams-DeVane, Karen Huen, Sheryl L Rifas-Shiman, Carlos Ruiz-Arenas, Semira Gonseth, Faisal I Rezwan, Zdenko Herceg, Sandra Ekström, Lisa Croen, Fahimeh Falahi, Patrice Perron, Margaret R Karagas, Bilal M Quraishi, Matthew Suderman, Maria C Magnus, Vincent W V Jaddoe, Jack A Taylor, Denise Anderson, Shanshan Zhao, Henriette A Smit, Michele J Josey, Asa Bradman, Andrea A Baccarelli, Mariona Bustamante, Siri E Håberg, Göran Pershagen, Irva Hertz-Picciotto, Craig Newschaffer, Eva Corpeleijn, Luigi Bouchard, Debbie A Lawlor, Rachel L Maguire, Lisa F Barcellos, George Davey Smith, Brenda Eskenazi, Wilfried Karmaus, Carmen J Marsit, Marie-France Hivert, Harold Snieder, M Daniele Fallin, Erik Melén, Monica C Munthe-Kaas, Hasan Arshad, Joseph L Wiemels, Isabella Annesi-Maesano, Martine Vrijheid, Emily Oken, Nina Holland, Susan K Murphy, Thorkild I A Sørensen, Gerard H Koppelman, John P Newnham, Allen J Wilcox, Wenche Nystad, Stephanie J London, Janine F Felix, Caroline L Relton
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
published pages: 4067-4085, ISSN: 0964-6906, DOI: 10.1093/hmg/ddx290
Human Molecular Genetics 26/20 2019-06-07
2017 Tamara Marinkovic, Liza Toemen, Claudia J. Kruithof, Irwin Reiss, Lennie van Osch-Gevers, Albert Hofman, Oscar H. Franco, Vincent W.V. Jaddoe
Early Infant Growth Velocity Patterns and Cardiovascular and Metabolic Outcomes in Childhood
published pages: , ISSN: 0022-3476, DOI: 10.1016/j.jpeds.2017.02.004
The Journal of Pediatrics 2019-06-07
2016 A A E Vinkhuyzen, D W Eyles, T H J Burne, L M E Blanken, C J Kruithof, F Verhulst, V W Jaddoe, H Tiemeier, J J McGrath
Gestational vitamin D deficiency and autism-related traits: the Generation R Study
published pages: , ISSN: 1359-4184, DOI: 10.1038/mp.2016.213
Molecular Psychiatry 2019-06-07
2017 Rebecca C. Richmond, Nicholas J. Timpson, Janine F. Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W. Jaddoe, Debbie A. Lawlor
Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study
published pages: e1002221, ISSN: 1549-1277, DOI: 10.1371/journal.pmed.1002221
PLOS Medicine 14/1 2019-06-07
2016 Susana Santos, Romy Gaillard, Andreia Oliveira, Henrique Barros, Albert Hofman, Oscar H. Franco, Vincent W.V. Jaddoe
Subcutaneous fat mass in infancy and cardiovascular risk factors at school-age: The generation R study
published pages: 424-429, ISSN: 1930-7381, DOI: 10.1002/oby.21343
Obesity 24/2 2019-06-07
2016 Claire Monnereau, Suzanne Vogelezang, Claudia J. Kruithof, Vincent W. V. Jaddoe, Janine F. Felix
Associations of genetic risk scores based on adult adiposity pathways with childhood growth and adiposity measures
published pages: , ISSN: 1471-2156, DOI: 10.1186/s12863-016-0425-y
BMC Genetics 17/1 2019-06-07
2016 Mariona Bustamante, Marie Standl, Quique Bassat, Natalia Vilor-Tejedor, Carolina Medina-Gomez, Carolina Bonilla, Tarunveer S. Ahluwalia, Jonas Bacelis, Jonathan P. Bradfield, Carla M.T. Tiesler, Fernando Rivadeneira, Susan Ring, Nadja H. Vissing, Nadia R. Fink, Astanand Jugessur, Frank D. Mentch, Ferran Ballester, Jennifer Kriebel, Jessica C. Kiefte-de Jong, Helene M. Wolsk, Sabrina Llop, Elisabeth Thiering, Systke A. Beth, Nicholas J. Timpson, Josefine Andersen, Holger Schulz, Vincent W.V. Jaddoe, David M. Evans, Johannes Waage, Hakon Hakonarson, Struan F.A. Grant, Bo Jacobsson, Klaus Bønnelykke, Hans Bisgaard, George Davey Smith, Henriette A. Moll, Joachim Heinrich, Xavier Estivill, Jordi Sunyer
A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways
published pages: 4127-4142, ISSN: 0964-6906, DOI: 10.1093/hmg/ddw264
Human Molecular Genetics 25/18 2019-06-07
2016 C J Kruithof, O Gishti, A Hofman, R Gaillard, V W V Jaddoe
Infant weight growth velocity patterns and general and abdominal adiposity in school-age children. The Generation R Study
published pages: 1144-1150, ISSN: 0954-3007, DOI: 10.1038/ejcn.2016.60
European Journal of Clinical Nutrition 70/10 2019-06-07
2017 Trudy Voortman, Myrte J. Tielemans, Wendy Stroobant, Josje D. Schoufour, Jessica C. Kiefte-de Jong, Jolien Steenweg-de Graaff, Edith H. van den Hooven, Henning Tiemeier, Vincent W.V. Jaddoe, Oscar H. Franco
Plasma fatty acid patterns during pregnancy and child\'s growth, body composition, and cardiometabolic health: The Generation R Study
published pages: , ISSN: 0261-5614, DOI: 10.1016/j.clnu.2017.04.006
Clinical Nutrition 2019-06-07
2016 Lea Kragt, Justin T. van der Tas, Henriëtte A. Moll, Marlies E.C. Elfrink, Vincent W.V. Jaddoe, Eppo B. Wolvius, Edwin M. Ongkosuwito
Early Caries Predicts Low Oral Health-Related Quality of Life at a Later Age
published pages: 471-479, ISSN: 0008-6568, DOI: 10.1159/000448599
Caries Research 50/5 2019-06-07
2016 Kozeta Miliku, Suzanne Vogelezang, Oscar H. Franco, Albert Hofman, Vincent W.V. Jaddoe, Janine F. Felix
Influence of common genetic variants on childhood kidney outcomes
published pages: 60-66, ISSN: 0031-3998, DOI: 10.1038/pr.2016.44
Pediatric Research 80/1 2019-06-07
2017 Lea Kragt, Eppo B. Wolvius, Vincent W. V. Jaddoe, Henning Tiemeier, Edwin M. Ongkosuwito
Influence of self-esteem on perceived orthodontic treatment need and oral health-related quality of life in children: the Generation R Study
published pages: , ISSN: 0141-5387, DOI: 10.1093/ejo/cjx054
European Journal of Orthodontics 2019-06-07
2015 Aleksandra Jelena Vidakovic, Vincent W. V. Jaddoe, Olta Gishti, Janine F. Felix, Michelle A. Williams, Albert Hofman, Hans Demmelmair, Berthold Koletzko, Henning Tiemeier, Romy Gaillard
Body mass index, gestational weight gain and fatty acid concentrations during pregnancy: the Generation R Study
published pages: 1175-1185, ISSN: 0393-2990, DOI: 10.1007/s10654-015-0106-6
European Journal of Epidemiology 30/11 2019-06-07
2016 MN Kooijman, R Gaillard, IKM Reiss, A Hofman, EAP Steegers, VWV Jaddoe
Influence of fetal blood flow redistribution on fetal and childhood growth and fat distribution: the Generation R Study
published pages: 2104-2112, ISSN: 1470-0328, DOI: 10.1111/1471-0528.13933
BJOG: An International Journal of Obstetrics & Gynaecology 123/13 2019-06-07
2016 Ellis Voerman, Vincent W.V. Jaddoe, Olta Gishti, Albert Hofman, Oscar H. Franco, Romy Gaillard
Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age
published pages: 1170-1177, ISSN: 1930-7381, DOI: 10.1002/oby.21466
Obesity 24/5 2019-06-07
2018 H. T. den Dekker, V. W.V. Jaddoe, I. K. Reiss, J. C. de Jongste, L. Duijts
Maternal folic acid use during pregnancy, methylenetetrahydrofolate reductase gene polymorphism, and child\'s lung function and asthma
published pages: 175-185, ISSN: 0954-7894, DOI: 10.1111/cea.13056
Clinical & Experimental Allergy 48/2 2019-06-07
2017 Janine F Felix, Bonnie R Joubert, Andrea A Baccarelli, Gemma C Sharp, Catarina Almqvist, Isabella Annesi-Maesano, Hasan Arshad, Nour Baïz, Marian J Bakermans-Kranenburg, Kelly M Bakulski, Elisabeth B Binder, Luigi Bouchard, Carrie V Breton, Bert Brunekreef, Kelly J Brunst, Esteban G Burchard, Mariona Bustamante, Leda Chatzi, Monica Cheng Munthe-Kaas, Eva Corpeleijn, Darina Czamara, Dana Dabelea, George Davey Smith, Patrick De Boever, Liesbeth Duijts, Terence Dwyer, Celeste Eng, Brenda Eskenazi, Todd M Everson, Fahimeh Falahi, M Daniele Fallin, Sara Farchi, Mariana F Fernandez, Lu Gao, Tom R Gaunt, Akram Ghantous, Matthew W Gillman, Semira Gonseth, Veit Grote, Olena Gruzieva, Siri E Håberg, Zdenko Herceg, Marie-France Hivert, Nina Holland, John W Holloway, Cathrine Hoyo, Donglei Hu, Rae-Chi Huang, Karen Huen, Marjo-Riitta Järvelin, Dereje D Jima, Allan C Just, Margaret R Karagas, Robert Karlsson, Wilfried Karmaus, Katerina J Kechris, Juha Kere, Manolis Kogevinas, Berthold Koletzko, Gerard H Koppelman, Leanne K Küpers, Christine Ladd-Acosta, Jari Lahti, Nathalie Lambrechts, Sabine AS Langie, Rolv T Lie, Andrew H Liu, Maria C Magnus, Per Magnus, Rachel L Maguire, Carmen J Marsit, Wendy McArdle, Erik Melén, Phillip Melton, Susan K Murphy, Tim S Nawrot, Lorenza Nisticò, Ellen A Nohr, Björn Nordlund, Wenche Nystad, Sam S Oh, Emily Oken, Christian M Page, Patrice Perron, Göran Pershagen, Costanza Pizzi, Michelle Plusquin, Katri Raikkonen, Sarah E Reese, Eva Reischl, Lorenzo Richiardi, Susan Ring, Ritu P Roy, Peter Rzehak, Greet Schoeters, David A Schwartz, Sylvain Sebert, Harold Snieder, Thorkild IA Sørensen, Anne P Starling, Jordi Sunyer, Jack A Taylor, Henning Tiemeier, Vilhelmina Ullemar, Marina Vafeiadi, Marinus H Van Ijzendoorn, Judith M Vonk, Annette Vriens, Martine Vrijheid, Pei Wang, Joseph L Wiemels, Allen J Wilcox, Rosalind J Wright, Cheng-Jian Xu, Zongli Xu, Ivana V Yang, Paul Yousefi, Hongmei Zhang, Weiming Zhang, Shanshan Zhao, Golareh Agha, Caroline L Relton, Vincent WV Jaddoe, Stephanie J London
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
published pages: 22-23u, ISSN: 0300-5771, DOI: 10.1093/ije/dyx190
International Journal of Epidemiology 47/1 2019-06-07
2017 Rosa H. Mulder, Jolien Rijlaarsdam, Maartje P. C. M. Luijk, Frank C. Verhulst, Janine F. Felix, Henning Tiemeier, Marian J. Bakermans-Kranenburg, Marinus H. Van Ijzendoorn
Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation
published pages: 491-503, ISSN: 0954-5794, DOI: 10.1017/S095457941700013X
Development and Psychopathology 29/02 2019-06-07
2017 Iris J. Grooten, Wouter J. Den Hollander, Tessa J. Roseboom, Ernst J. Kuipers, Vincent W. Jaddoe, Romy Gaillard, Rebecca C. Painter
Helicobacter pylori infection: a predictor of vomiting severity in pregnancy and adverse birth outcome
published pages: , ISSN: 0002-9378, DOI: 10.1016/j.ajog.2017.01.042
American Journal of Obstetrics and Gynecology 2019-06-07
2015 K. Miliku, T. Voortman, E. H. van den Hooven, A. Hofman, O. H. Franco, V. W. Jaddoe
First-trimester maternal protein intake and childhood kidney outcomes: the Generation R Study
published pages: 123-129, ISSN: 0002-9165, DOI: 10.3945/ajcn.114.102228
American Journal of Clinical Nutrition 102/1 2019-06-07
2017 Liza Toemen, Romy Gaillard, Lennie van Osch-gevers, Willem A Helbing, Albert Hofman, Vincent WV Jaddoe
Tracking of structural and functional cardiac measures from infancy into school-age
published pages: 1408-1415, ISSN: 2047-4873, DOI: 10.1177/2047487317715512
European Journal of Preventive Cardiology 24/13 2019-06-07
2017 Pauline W. Jansen, Lisanne M. de Barse, Vincent W.V. Jaddoe, Frank C. Verhulst, Oscar H. Franco, Henning Tiemeier
Bi-directional associations between child fussy eating and parents\' pressure to eat: Who influences whom?
published pages: , ISSN: 0031-9384, DOI: 10.1016/j.physbeh.2017.02.015
Physiology & Behavior 2019-06-07
2015 Sunayna Bahadoer, Romy Gaillard, Janine F. Felix, Hein Raat, Carry M. Renders, Albert Hofman, Eric A.P. Steegers, Vincent W.V. Jaddoe
Ethnic disparities in maternal obesity and weight gain during pregnancy. The Generation R Study
published pages: 51-60, ISSN: 0301-2115, DOI: 10.1016/j.ejogrb.2015.06.031
European Journal of Obstetrics & Gynecology and Reproductive Biology 193 2019-06-07
2017 Ivonne P.M. Derks, Desana Kocevska, Vincent W.V. Jaddoe, Oscar H. Franco, Melissa Wake, Henning Tiemeier, Pauline W. Jansen
Longitudinal Associations of Sleep Duration in Infancy and Early Childhood with Body Composition and Cardiometabolic Health at the Age of 6 Years: The Generation R Study
published pages: 400-408, ISSN: 2153-2168, DOI: 10.1089/chi.2016.0341
Childhood Obesity 13/5 2019-06-07
2018 Evelien R van Meel, Herman T den Dekker, Niels J Elbert, Pauline W Jansen, Henriëtte A Moll, Irwin K Reiss, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
A population-based prospective cohort study examining the influence of early-life respiratory tract infections on school-age lung function and asthma
published pages: 167-173, ISSN: 0040-6376, DOI: 10.1136/thoraxjnl-2017-210149
Thorax 73/2 2019-06-07
2017 Evelien R. van Meel, Vincent W. V. Jaddoe, Klaus Bønnelykke, Johan C. de Jongste, Liesbeth Duijts
The role of respiratory tract infections and the microbiome in the development of asthma: A narrative review
published pages: 1363-1370, ISSN: 8755-6863, DOI: 10.1002/ppul.23795
Pediatric Pulmonology 52/10 2019-06-07
2017 Lea Kragt, Eppo B. Wolvius, Hein Raat, Vincent W. V. Jaddoe, Edwin M. Ongkosuwito
Social inequalities in children’s oral health-related quality of life: the Generation R Study
published pages: 3429-3437, ISSN: 0962-9343, DOI: 10.1007/s11136-017-1679-1
Quality of Life Research 26/12 2019-06-07
2018 Florence Demenais, Patricia Margaritte-Jeannin, Kathleen C. Barnes, William O. C. Cookson, Janine Altmüller, Wei Ang, R. Graham Barr, Terri H. Beaty, Allan B. Becker, John Beilby, Hans Bisgaard, Unnur Steina Bjornsdottir, Eugene Bleecker, Klaus Bønnelykke, Dorret I. Boomsma, Emmanuelle Bouzigon, Christopher E. Brightling, Myriam Brossard, Guy G. Brusselle, Esteban Burchard, Kristin M. Burkart, Andrew Bush, Moira Chan-Yeung, Kian Fan Chung, Alexessander Couto Alves, John A. Curtin, Adnan Custovic, Denise Daley, Johan C. de Jongste, Blanca E. Del-Rio-Navarro, Kathleen M. Donohue, Liesbeth Duijts, Celeste Eng, Johan G. Eriksson, Martin Farrall, Yuliya Fedorova, Bjarke Feenstra, Manuel A. Ferreira, Maxim B. Freidin, Zofia Gajdos, Jim Gauderman, Ulrike Gehring, Frank Geller, Jon Genuneit, Sina A. Gharib, Frank Gilliland, Raquel Granell, Penelope E. Graves, Daniel F. Gudbjartsson, Tari Haahtela, Susan R. Heckbert, Dick Heederik, Joachim Heinrich, Markku Heliövaara, John Henderson, Blanca E. Himes, Hiroshi Hirose, Joel N. Hirschhorn, Albert Hofman, Patrick Holt, Jouke Hottenga, Thomas J. Hudson, Jennie Hui, Medea Imboden, Vladimir Ivanov, Vincent W. V. Jaddoe, Alan James, Christer Janson, Marjo-Riitta Jarvelin, Deborah Jarvis, Graham Jones, Ingileif Jonsdottir, Pekka Jousilahti, Michael Kabesch, Mika Kähönen, David B. Kantor, Alexandra S. Karunas, Elza Khusnutdinova, Gerard H. Koppelman, Anita L. Kozyrskyj, Eskil Kreiner, Michiaki Kubo, Rajesh Kumar, Ashish Kumar, Mikko Kuokkanen, Lies Lahousse, Tarja Laitinen, Catherine Laprise, Mark Lathrop, Susanne Lau, Young-Ae Lee, Terho Lehtimäki, Sébastien Letort, Albert M. Levin, Guo Li, Liming Liang, Laura R. Loehr, Stephanie J. London, Daan W. Loth, Ani Manichaikul, Ingo Marenholz, Fernando J. Martinez, Melanie C. Matheson, Rasika A. Mathias, Kenji Matsumoto, Hamdi Mbarek, Wendy L. McArdle, Mads Melbye, Erik Melén, Deborah Meyers, Sven Michel, Hamida Mohamdi, Arthur W. Musk, Rachel A. Myers, Maartje A. E. Nieuwenhuis, Emiko Noguchi, George T. O’Connor, Ludmila M. Ogorodova, Cameron D. Palmer, Aarno Palotie, Julie E. Park, Craig E. Pennell, Göran Pershagen, Alexey Polonikov, Dirkje S. Postma, Nicole Probst-Hensch, Valery P. Puzyrev, Benjamin A. Raby, Olli T. Raitakari, Adaikalavan Ramasamy, Stephen S. Rich, Colin F. Robertson, Isabelle Romieu, Muhammad T. Salam, Veikko Salomaa, Vivi Schlünssen, Robert Scott, Polina A. Selivanova, Torben Sigsgaard, Angela Simpson, Valérie Siroux, Lewis J. Smith, Maria Solodilova, Marie Standl, Kari Stefansson, David P. Strachan, Bruno H. Stricker, Atsushi Takahashi, Philip J. Thompson, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Carla M. T. Tiesler, Dara G. Torgerson, Tatsuhiko Tsunoda, André G. Uitterlinden, Ralf J. P. van der Valk, Amaury Vaysse, Sailaja Vedantam, Andrea von Berg, Erika von Mutius, Judith M. Vonk, Johannes Waage, Nick J. Wareham, Scott T. Weiss, Wendy B. White, Magnus Wickman, Elisabeth Widén, Gonneke Willemsen, L. Keoki Williams, Inge M. Wouters, James J. Yang, Jing Hua Zhao, Miriam F. Moffatt, Carole Ober, Dan L. Nicolae
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
published pages: 42-53, ISSN: 1061-4036, DOI: 10.1038/s41588-017-0014-7
Nature Genetics 50/1 2019-06-07
2017 Justin T. van der Tas, Lea Kragt, Marlies E.C. Elfrink, Loes C.M. Bertens, Vincent W.V. Jaddoe, Henriëtte A. Moll, Edwin M. Ongkosuwito, Eppo B. Wolvius
Social inequalities and dental caries in six-year-old children from the Netherland s
published pages: 18-24, ISSN: 0300-5712, DOI: 10.1016/j.jdent.2017.04.008
Journal of Dentistry 62 2019-06-07
2016 Bonnie R. Joubert, Janine F. Felix, Paul Yousefi, Kelly M. Bakulski, Allan C. Just, Carrie Breton, Sarah E. Reese, Christina A. Markunas, Rebecca C. Richmond, Cheng-Jian Xu, Leanne K. Küpers, Sam S. Oh, Cathrine Hoyo, Olena Gruzieva, Cilla Söderhäll, Lucas A. Salas, Nour Baïz, Hongmei Zhang, Johanna Lepeule, Carlos Ruiz, Symen Ligthart, Tianyuan Wang, Jack A. Taylor, Liesbeth Duijts, Gemma C. Sharp, Soesma A. Jankipersadsing, Roy M. Nilsen, Ahmad Vaez, M. Daniele Fallin, Donglei Hu, Augusto A. Litonjua, Bernard F. Fuemmeler, Karen Huen, Juha Kere, Inger Kull, Monica Cheng Munthe-Kaas, Ulrike Gehring, Mariona Bustamante, Marie José Saurel-Coubizolles, Bilal M. Quraishi, Jie Ren, Jörg Tost, Juan R. Gonzalez, Marjolein J. Peters, Siri E. Håberg, Zongli Xu, Joyce B. van Meurs, Tom R. Gaunt, Marjan Kerkhof, Eva Corpeleijn, Andrew P. Feinberg, Celeste Eng, Andrea A. Baccarelli, Sara E. Benjamin Neelon, Asa Bradman, Simon Kebede Merid, Anna Bergström, Zdenko Herceg, Hector Hernandez-Vargas, Bert Brunekreef, Mariona Pinart, Barbara Heude, Susan Ewart, Jin Yao, Nathanaël Lemonnier, Oscar H. Franco, Michael C. Wu, Albert Hofman, Wendy McArdle, Pieter Van der Vlies, Fahimeh Falahi, Matthew W. Gillman, Lisa F. Barcellos, Ashish Kumar, Magnus Wickman, Stefano Guerra, Marie-Aline Charles, John Holloway, Charles Auffray, Henning W. Tiemeier, George Davey Smith, Dirkje Postma, Marie-France Hivert, Brenda Eskenazi, Martine Vrijheid, Hasan Arshad, Josep M. Antó, Abbas Dehghan, Wilfried Karmaus, Isabella Annesi-Maesano, Jordi Sunyer, Akram Ghantous, Göran Pershagen, Nina Holland, Susan K. Murphy, Dawn L. DeMeo, Esteban G. Burchard, Christine Ladd-Acosta, Harold Snieder, Wenche Nystad, Gerard H. Koppelman, Caroline L. Relton, Vincent W.V. Jaddoe, Allen Wilcox, Erik Melén, Stephanie J. London
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
published pages: 680-696, ISSN: 0002-9297, DOI: 10.1016/j.ajhg.2016.02.019
The American Journal of Human Genetics 98/4 2019-06-07
2017 Lea Kragt, Vincent Jaddoe, Eppo Wolvius, Edwin Ongkosuwito
The association of subjective orthodontic treatment need with oral health-related quality of life
published pages: , ISSN: 0301-5661, DOI: 10.1111/cdoe.12299
Community Dentistry and Oral Epidemiology 2019-06-07
2017 Elise M. Philips, Vincent W.V. Jaddoe, Leonardo Trasande
Effects of early exposure to phthalates and bisphenols on cardiometabolic outcomes in pregnancy and childhood
published pages: 105-118, ISSN: 0890-6238, DOI: 10.1016/j.reprotox.2016.08.015
Reproductive Toxicology 68 2019-06-07
2017 Evelien R. van Meel, Mandy de Jong, Niels J. Elbert, Herman T. den Dekker, Irwin K. Reiss, Johan C. de Jongste, Vincent W.V. Jaddoe, Liesbeth Duijts
Duration and exclusiveness of breastfeeding and school-age lung function and asthma
published pages: 21-26.e2, ISSN: 1081-1206, DOI: 10.1016/j.anai.2017.05.002
Annals of Allergy, Asthma & Immunology 119/1 2019-06-07
2017 Ioanna Tachmazidou, Dániel Süveges, Josine L. Min, Graham R.S. Ritchie, Julia Steinberg, Klaudia Walter, Valentina Iotchkova, Jeremy Schwartzentruber, Jie Huang, Yasin Memari, Shane McCarthy, Andrew A. Crawford, Cristina Bombieri, Massimiliano Cocca, Aliki-Eleni Farmaki, Tom R. Gaunt, Pekka Jousilahti, Marjolein N. Kooijman, Benjamin Lehne, Giovanni Malerba, Satu Männistö, Angela Matchan, Carolina Medina-Gomez, Sarah J. Metrustry, Abhishek Nag, Ioanna Ntalla, Lavinia Paternoster, Nigel W. Rayner, Cinzia Sala, William R. Scott, Hashem A. Shihab, Lorraine Southam, Beate St Pourcain, Michela Traglia, Katerina Trajanoska, Gialuigi Zaza, Weihua Zhang, María S. Artigas, Narinder Bansal, Marianne Benn, Zhongsheng Chen, Petr Danecek, Wei-Yu Lin, Adam Locke, Jian’an Luan, Alisa K. Manning, Antonella Mulas, Carlo Sidore, Anne Tybjaerg-Hansen, Anette Varbo, Magdalena Zoledziewska, Chris Finan, Konstantinos Hatzikotoulas, Audrey E. Hendricks, John P. Kemp, Alireza Moayyeri, Kalliope Panoutsopoulou, Michal Szpak, Scott G. Wilson, Michael Boehnke, Francesco Cucca, Emanuele Di Angelantonio, Claudia Langenberg, Cecilia Lindgren, Mark I. McCarthy, Andrew P. Morris, Børge G. Nordestgaard, Robert A. Scott, Martin D. Tobin, Nicholas J. Wareham, Paul Burton, John C. Chambers, George Davey Smith, George Dedoussis, Janine F. Felix, Oscar H. Franco, Giovanni Gambaro, Paolo Gasparini, Christopher J. Hammond, Albert Hofman, Vincent W.V. Jaddoe, Marcus Kleber, Jaspal S. Kooner, Markus Perola, Caroline Relton, Susan M. Ring, Fernando Rivadeneira, Veikko Salomaa, Timothy D. Spector, Oliver Stegle, Daniela Toniolo, André G. Uitterlinden, Inês Barroso, Celia M.T. Greenwood, John R.B. Perry, Brian R. Walker, Adam S. Butterworth, Yali Xue, Richard Durbin, Kerrin S. Small, Nicole Soranzo, Nicholas J. Timpson, Eleftheria Zeggini
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
published pages: 865-884, ISSN: 0002-9297, DOI: 10.1016/j.ajhg.2017.04.014
The American Journal of Human Genetics 100/6 2019-06-07
2018 Robin N Beaumont, Nicole M Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C Richmond, Lavinia Paternoster, Jonathan P Bradfield, Eskil Kreiner-Møller, Ville Huikari, Sarah Metrustry, Kathryn L Lunetta, Jodie N Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J Barton, Ana Espinosa, Julie A Marsh, Catherine Potter, Ge Zhang, Wei Ang, Diane J Berry, Luigi Bouchard, Shikta Das, Hakon Hakonarson, Jani Heikkinen, Øyvind Helgeland, Berthold Hocher, Albert Hofman, Hazel M Inskip, Samuel E Jones, Manolis Kogevinas, Penelope A Lind, Letizia Marullo, Sarah E Medland, Anna Murray, Jeffrey C Murray, Pål R Njølstad, Ellen A Nohr, Christoph Reichetzeder, Susan M Ring, Katherine S Ruth, Loreto Santa-Marina, Denise M Scholtens, Sylvain Sebert, Verena Sengpiel, Marcus A Tuke, Marc Vaudel, Michael N Weedon, Gonneke Willemsen, Andrew R Wood, Hanieh Yaghootkar, Louis J Muglia, Meike Bartels, Caroline L Relton, Craig E Pennell, Leda Chatzi, Xavier Estivill, John W Holloway, Dorret I Boomsma, Grant W Montgomery, Joanne M Murabito, Tim D Spector, Christine Power, Marjo-Ritta Järvelin, Hans Bisgaard, Struan F A Grant, Thorkild I A Sørensen, Vincent W Jaddoe, Bo Jacobsson, Mads Melbye, Mark I McCarthy, Andrew T Hattersley, M Geoffrey Hayes, Timothy M Frayling, Marie-France Hivert, Janine F Felix, Elina Hyppönen, William L Lowe, David M Evans, Debbie A Lawlor, Bjarke Feenstra, Rachel M Freathy
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
published pages: 742-756, ISSN: 0964-6906, DOI: 10.1093/hmg/ddx429
Human Molecular Genetics 27/4 2019-06-07
2018 Sabrina M. C. B. Pereira de Jesus, Herman T. den Dekker, Johan C. de Jongste, Irwin K. Reiss, Eric A. Steegers, Vincent W. V. Jaddoe, Liesbeth Duijts
Maternal hemoglobin and hematocrit levels during pregnancy and childhood lung function and asthma. The Generation R Study
published pages: 130-137, ISSN: 8755-6863, DOI: 10.1002/ppul.23733
Pediatric Pulmonology 53/2 2019-06-07
2016 Momoko Horikoshi, Robin N. Beaumont, Felix R. Day, Nicole M. Warrington, Marjolein N. Kooijman, Juan Fernandez-Tajes, Bjarke Feenstra, Natalie R. van Zuydam, Kyle J. Gaulton, Niels Grarup, Jonathan P. Bradfield, David P. Strachan, Ruifang Li-Gao, Tarunveer S. Ahluwalia, Eskil Kreiner, Rico Rueedi, Leo-Pekka Lyytikäinen, Diana L. Cousminer, Ying Wu, Elisabeth Thiering, Carol A. Wang, Christian T. Have, Jouke-Jan Hottenga, Natalia Vilor-Tejedor, Peter K. Joshi, Eileen Tai Hui Boh, Ioanna Ntalla, Niina Pitkänen, Anubha Mahajan, Elisabeth M. van Leeuwen, Raimo Joro, Vasiliki Lagou, Michael Nodzenski, Louise A. Diver, Krina T. Zondervan, Mariona Bustamante, Pedro Marques-Vidal, Josep M. Mercader, Amanda J. Bennett, Nilufer Rahmioglu, Dale R. Nyholt, Ronald C. W. Ma, Claudia H. T. Tam, Wing Hung Tam, Santhi K. Ganesh, Frank J. A. van Rooij, Samuel E. Jones, Po-Ru Loh, Katherine S. Ruth, Marcus A. Tuke, Jessica Tyrrell, Andrew R. Wood, Hanieh Yaghootkar, Denise M. Scholtens, Lavinia Paternoster, Inga Prokopenko, Peter Kovacs, Mustafa Atalay, Sara M. Willems, Kalliope Panoutsopoulou, Xu Wang, Lisbeth Carstensen, Frank Geller, Katharina E. Schraut, Mario Murcia, Catharina E. M. van Beijsterveldt, Gonneke Willemsen, Emil V. R. Appel, Cilius E. Fonvig, Caecilie Trier, Carla M. T. Tiesler, Marie Standl, Zoltán Kutalik, Sílvia Bonàs-Guarch, David M. Hougaard, Friman Sánchez, David Torrents, Johannes Waage, Mads V. Hollegaard, Hugoline G. de Haan, Frits R. Rosendaal, Carolina Medina-Gomez, Susan M. Ring, Gibran Hemani, George McMahon, Neil R. Robertson, Christopher J. Groves, Claudia Langenberg, Jian’an Luan, Robert A. Scott, Jing Hua Zhao, Frank D. Mentch, Scott M. MacKenzie, Rebecca M. Reynolds, William L. Lowe, Anke Tönjes, Michael Stumvoll, Virpi Lindi, Timo A. Lakka, Cornelia M. van Duijn, Wieland Kiess, Antje Körner, Thorkild I. A. Sørensen, Harri Niinikoski, Katja Pahkala, Olli T. Raitakari, Eleftheria Zeggini, George V. Dedoussis, Yik-Ying Teo, Seang-Mei Saw, Mads Melbye, Harry Campbell, James F. Wilson, Martine Vrijheid, Eco J. C. N. de Geus, Dorret I. Boomsma, Haja N. Kadarmideen, Jens-Christian Holm, Torben Hansen, Sylvain Sebert, Andrew T. Hattersley, Lawrence J. Beilin, John P. Newnham, Craig E. Pennell, Joachim Heinrich, Linda S. Adair, Judith B. Borja, Karen L. Mohlke, Johan G. Eriksson, Elisabeth Widén, Mika Kähönen, Jorma S. Viikari, Terho Lehtimäki, Peter Vollenweider, Klaus Bønnelykke, Hans Bisgaard, Dennis O. Mook-Kanamori, Albert Hofman, Fernando Rivadeneira, André G. Uitterlinden, Charlotta Pisinger, Oluf Pedersen, Christine Power, Elina Hyppönen, Nicholas J. Wareham, Hakon Hakonarson, Eleanor Davies, Brian R. Walker, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Struan F. A. Grant, Allan A. Vaag, Debbie A. Lawlor, Timothy M. Frayling, George Davey Smith, Andrew P. Morris, Ken K. Ong, Janine F. Felix, Nicholas J. Timpson, John R. B. Perry, David M. Evans, Mark I. McCarthy, Rachel M. Freathy
Genome-wide associations for birth weight and correlations with adult disease
published pages: 248-252, ISSN: 0028-0836, DOI: 10.1038/nature19806
Nature 538/7624 2019-06-07
2015 Carolina Medina-Gómez, Alessandra Chesi, Denise H.M. Heppe, Babette S. Zemel, Jia-Lian Yin, Heidi J. Kalkwarf, Albert Hofman, Joan M. Lappe, Andrea Kelly, Manfred Kayser, Sharon E. Oberfield, Vicente Gilsanz, André G. Uitterlinden, John A. Shepherd, Vincent W.V. Jaddoe, Struan F.A. Grant, Oscar Lao, Fernando Rivadeneira
BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures
published pages: 2961-2972, ISSN: 0737-4038, DOI: 10.1093/molbev/msv170
Molecular Biology and Evolution 32/11 2019-06-07
2017 Hanneke Bakker, Romy Gaillard, Albert Hofman, Irwin K. Reiss, Eric A. P. Steegers, Vincent W. V. Jaddoe
Fetal first trimester growth is not associated with kidney outcomes in childhood
published pages: 651-658, ISSN: 0931-041X, DOI: 10.1007/s00467-016-3537-8
Pediatric Nephrology 32/4 2019-06-07
2016 Aleksandra Jelena Vidakovic, Susana Santos, Michelle A. Williams, Liesbeth Duijts, Albert Hofman, Hans Demmelmair, Berthold Koletzko, Vincent W.V. Jaddoe, Romy Gaillard
Maternal plasma n-3 and n-6 polyunsaturated fatty acid concentrations during pregnancy and subcutaneous fat mass in infancy
published pages: 1759-1766, ISSN: 1930-7381, DOI: 10.1002/oby.21547
Obesity 24/8 2019-06-07
2017 Varsha V. Jharap, Susana Santos, Eric A.P. Steegers, Vincent W.V. Jaddoe, Romy Gaillard
Associations of maternal obesity and excessive weight gain during pregnancy with subcutaneous fat mass in infancy
published pages: 23-28, ISSN: 0378-3782, DOI: 10.1016/j.earlhumdev.2017.03.006
Early Human Development 108 2019-06-07
2018 Carolina Medina-Gomez, John P. Kemp, Katerina Trajanoska, Jian’an Luan, Alessandra Chesi, Tarunveer S. Ahluwalia, Dennis O. Mook-Kanamori, Annelies Ham, Fernando P. Hartwig, Daniel S. Evans, Raimo Joro, Ivana Nedeljkovic, Hou-Feng Zheng, Kun Zhu, Mustafa Atalay, Ching-Ti Liu, Maria Nethander, Linda Broer, Gudmar Porleifsson, Benjamin H. Mullin, Samuel K. Handelman, Mike A. Nalls, Leon E. Jessen, Denise H.M. Heppe, J. Brent Richards, Carol Wang, Bo Chawes, Katharina E. Schraut, Najaf Amin, Nick Wareham, David Karasik, Nathalie Van der Velde, M. Arfan Ikram, Babette S. Zemel, Yanhua Zhou, Christian J. Carlsson, Yongmei Liu, Fiona E. McGuigan, Cindy G. Boer, Klaus Bønnelykke, Stuart H. Ralston, John A. Robbins, John P. Walsh, M. Carola Zillikens, Claudia Langenberg, Ruifang Li-Gao, Frances M.K. Williams, Tamara B. Harris, Kristina Akesson, Rebecca D. Jackson, Gunnar Sigurdsson, Martin den Heijer, Bram C.J. van der Eerden, Jeroen van de Peppel, Timothy D. Spector, Craig Pennell, Bernardo L. Horta, Janine F. Felix, Jing Hua Zhao, Scott G. Wilson, Renée de Mutsert, Hans Bisgaard, Unnur Styrkársdóttir, Vincent W. Jaddoe, Eric Orwoll, Timo A. Lakka, Robert Scott, Struan F.A. Grant, Mattias Lorentzon, Cornelia M. van Duijn, James F. Wilson, Kari Stefansson, Bruce M. Psaty, Douglas P. Kiel, Claes Ohlsson, Evangelia Ntzani, Andre J. van Wijnen, Vincenzo Forgetta, Mohsen Ghanbari, John G. Logan, Graham R. Williams, J.H. Duncan Bassett, Peter I. Croucher, Evangelos Evangelou, Andre G. Uitterlinden, Cheryl L. Ackert-Bicknell, Jonathan H. Tobias, David M. Evans, Fernando Rivadeneira
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
published pages: 88-102, ISSN: 0002-9297, DOI: 10.1016/j.ajhg.2017.12.005
The American Journal of Human Genetics 102/1 2019-06-07
2017 Claire Monnereau, Pauline W. Jansen, Henning Tiemeier, Vincent W.V. Jaddoe, Janine F. Felix
Influence of genetic variants associated with body mass index on eating behavior in childhood
published pages: 765-772, ISSN: 1930-7381, DOI: 10.1002/oby.21778
Obesity 25/4 2019-06-07
2017 Anna A. E. Vinkhuyzen, Darryl W. Eyles, Thomas H. J. Burne, Laura M. E. Blanken, Claudia J. Kruithof, Frank Verhulst, Tonya White, Vincent W. Jaddoe, Henning Tiemeier, John J. McGrath
Gestational vitamin D deficiency and autism spectrum disorder
published pages: 85-90, ISSN: 2056-4724, DOI: 10.1192/bjpo.bp.116.004077
BJPsych Open 3/02 2019-06-07
2017 Kozeta Miliku, Hanneke Bakker, Eiske M. Dorresteijn, Karlien Cransberg, Oscar H. Franco, Janine F. Felix, Vincent W.V. Jaddoe
Childhood Estimates of Glomerular Filtration Rate Based on Creatinine and Cystatin C: Importance of Body Composition
published pages: 320-326, ISSN: 0250-8095, DOI: 10.1159/000463395
American Journal of Nephrology 45/4 2019-06-07
2018 Laura A. van der Velde, Anh N. Nguyen, Josje D. Schoufour, Anouk Geelen, Vincent W. V. Jaddoe, Oscar H. Franco, Trudy Voortman
Diet quality in childhood: the Generation R Study
published pages: , ISSN: 1436-6207, DOI: 10.1007/s00394-018-1651-z
European Journal of Nutrition 2019-06-07
2017 Valentina Gallo, F. Nicole Dijk, John W. Holloway, Susan M. Ring, Gerard H. Koppelman, Dirkje S. Postma, David P. Strachan, Raquel Granell, Johan C. de Jongste, Vincent W. V. Jaddoe, Herman T. den Dekker, Liesbeth Duijts, A. John Henderson, Seif O. Shaheen
TRPA1 gene polymorphisms and childhood asthma
published pages: 191-198, ISSN: 0905-6157, DOI: 10.1111/pai.12673
Pediatric Allergy and Immunology 28/2 2019-06-07
2017 Kozeta Miliku, Anne Mesu, Oscar H. Franco, Albert Hofman, Eric A.P. Steegers, Vincent W.V. Jaddoe
Maternal and Fetal Folate, Vitamin B 12 , and Homocysteine Concentrations and Childhood Kidney Outcomes
published pages: 521-530, ISSN: 0272-6386, DOI: 10.1053/j.ajkd.2016.11.014
American Journal of Kidney Diseases 69/4 2019-06-07
2017 A.J. Vidakovic, V.W.V. Jaddoe, T. Voortman, H. Demmelmair, B. Koletzko, R. Gaillard
Maternal plasma polyunsaturated fatty acid levels during pregnancy and childhood lipid and insulin levels
published pages: 78-85, ISSN: 0939-4753, DOI: 10.1016/j.numecd.2016.10.001
Nutrition, Metabolism and Cardiovascular Diseases 27/1 2019-06-07
2017 Małgorzata J. Lubczyńska, Jordi Sunyer, Henning Tiemeier, Daniela Porta, Monika Kasper-Sonnenberg, Vincent W.V. Jaddoe, Xavier Basagaña, Albert Dalmau-Bueno, Francesco Forastiere, Jürgen Wittsiepe, Barbara Hoffmann, Mark Nieuwenhuijsen, Gerard Hoek, Kees de Hoogh, Bert Brunekreef, Mònica Guxens
Exposure to elemental composition of outdoor PM 2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts
published pages: 170-180, ISSN: 0160-4120, DOI: 10.1016/j.envint.2017.09.015
Environment International 109 2019-06-07
2016 Kozeta Miliku, Nienke E. Bergen, Hanneke Bakker, Albert Hofman, Eric A. P. Steegers, Romy Gaillard, Vincent W. V. Jaddoe
Associations of Maternal and Paternal Blood Pressure Patterns and Hypertensive Disorders during Pregnancy with Childhood Blood Pressure
published pages: e003884, ISSN: 2047-9980, DOI: 10.1161/JAHA.116.003884
Journal of the American Heart Association 5/10 2019-06-07
2015 K Miliku, T Voortman, O H Franco, J J McGrath, D W Eyles, T H Burne, A Hofman, H Tiemeier, V W V Jaddoe
Vitamin D status during fetal life and childhood kidney outcomes
published pages: 629-634, ISSN: 0954-3007, DOI: 10.1038/ejcn.2015.216
European Journal of Clinical Nutrition 70/5 2019-06-07
2017 Ellis Voerman, Vincent W. V. Jaddoe, Oscar H. Franco, Eric A. P. Steegers, Romy Gaillard
Critical periods and growth patterns from fetal life onwards associated with childhood insulin levels
published pages: 81-88, ISSN: 0012-186X, DOI: 10.1007/s00125-016-4135-9
Diabetologia 60/1 2019-06-07
2016 Bonnie R. Joubert, Herman T. den Dekker, Janine F. Felix, Jon Bohlin, Symen Ligthart, Emma Beckett, Henning Tiemeier, Joyce B. van Meurs, Andre G. Uitterlinden, Albert Hofman, Siri E. Håberg, Sarah E. Reese, Marjolein J. Peters, Bettina Kulle Andreassen, Eric A. P. Steegers, Roy M. Nilsen, Stein E. Vollset, Øivind Midttun, Per M. Ueland, Oscar H. Franco, Abbas Dehghan, Johan C. de Jongste, Michael C. Wu, Tianyuan Wang, Shyamal D. Peddada, Vincent W. V. Jaddoe, Wenche Nystad, Liesbeth Duijts, Stephanie J. London
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
published pages: 10577, ISSN: 2041-1723, DOI: 10.1038/ncomms10577
Nature Communications 7 2019-06-07
2016 Jolien Rijlaarsdam, Irene Pappa, Esther Walton, Marian J. Bakermans-Kranenburg, Viara R. Mileva-Seitz, Ralph C.A. Rippe, Sabine J. Roza, Vincent W.V. Jaddoe, Frank C. Verhulst, Janine F. Felix, Charlotte A.M. Cecil, Caroline L. Relton, Tom R. Gaunt, Wendy McArdle, Jonathan Mill, Edward D. Barker, Henning Tiemeier, Marinus H. van IJzendoorn
An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication
published pages: 140-149, ISSN: 1559-2294, DOI: 10.1080/15592294.2016.1145329
Epigenetics 11/2 2019-06-07
2016 Janine F. Felix, Jonathan P. Bradfield, Claire Monnereau, Ralf J.P. van der Valk, Evie Stergiakouli, Alessandra Chesi, Romy Gaillard, Bjarke Feenstra, Elisabeth Thiering, Eskil Kreiner-Møller, Anubha Mahajan, Niina Pitkänen, Raimo Joro, Alana Cavadino, Ville Huikari, Steve Franks, Maria M. Groen-Blokhuis, Diana L. Cousminer, Julie A. Marsh, Terho Lehtimäki, John A. Curtin, Jesus Vioque, Tarunveer S. Ahluwalia, Ronny Myhre, Thomas S. Price, Natalia Vilor-Tejedor, Loïc Yengo, Niels Grarup, Ioanna Ntalla, Wei Ang, Mustafa Atalay, Hans Bisgaard, Alexandra I. Blakemore, Amelie Bonnefond, Lisbeth Carstensen, Johan Eriksson, Claudia Flexeder, Lude Franke, Frank Geller, Mandy Geserick, Anna-Liisa Hartikainen, Claire M.A. Haworth, Joel N. Hirschhorn, Albert Hofman, Jens-Christian Holm, Momoko Horikoshi, Jouke Jan Hottenga, Jinyan Huang, Haja N. Kadarmideen, Mika Kähönen, Wieland Kiess, Hanna-Maaria Lakka, Timo A. Lakka, Alexandra M. Lewin, Liming Liang, Leo-Pekka Lyytikäinen, Baoshan Ma, Per Magnus, Shana E. McCormack, George McMahon, Frank D. Mentch, Christel M. Middeldorp, Clare S. Murray, Katja Pahkala, Tune H. Pers, Roland Pfäffle, Dirkje S. Postma, Christine Power, Angela Simpson, Verena Sengpiel, Carla M. T. Tiesler, Maties Torrent, André G. Uitterlinden, Joyce B. van Meurs, Rebecca Vinding, Johannes Waage, Jane Wardle, Eleftheria Zeggini, Babette S. Zemel, George V. Dedoussis, Oluf Pedersen, Philippe Froguel, Jordi Sunyer, Robert Plomin, Bo Jacobsson, Torben Hansen, Juan R. Gonzalez, Adnan Custovic, Olli T. Raitakari, Craig E. Pennell, Elisabeth Widén, Dorret I. Boomsma, Gerard H. Koppelman, Sylvain Sebert, Marjo-Riitta Järvelin, Elina Hyppönen, Mark I. McCarthy, Virpi Lindi, Niinikoski Harri, Antje Körner, Klaus Bønnelykke, Joachim Heinrich, Mads Melbye, Fernando Rivadeneira, Hakon Hakonarson, Susan M. Ring, George Davey Smith, Thorkild I.A. Sørensen, Nicholas J. Timpson, Struan F.A. Grant, Vincent W.V. Jaddoe
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
published pages: 389-403, ISSN: 0964-6906, DOI: 10.1093/hmg/ddv472
Human Molecular Genetics 25/2 2019-06-07
2016 K. Miliku, A. Vinkhuyzen, L. M. Blanken, J. J. McGrath, D. W. Eyles, T. H. Burne, A. Hofman, H. Tiemeier, E. A. Steegers, R. Gaillard, V. W. Jaddoe
Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes
published pages: 1514-1522, ISSN: 0002-9165, DOI: 10.3945/ajcn.115.123752
American Journal of Clinical Nutrition 103/6 2019-06-07
2017 Olena Gruzieva, Cheng-Jian Xu, Carrie V. Breton, Isabella Annesi-Maesano, Josep M. Antó, Charles Auffray, Stéphane Ballereau, Tom Bellander, Jean Bousquet, Mariona Bustamante, Marie-Aline Charles, Yvonne de Kluizenaar, Herman T. den Dekker, Liesbeth Duijts, Janine F. Felix, Ulrike Gehring, Mònica Guxens, Vincent V.W. Jaddoe, Soesma A. Jankipersadsing, Simon Kebede Merid, Juha Kere, Ashish Kumar, Nathanael Lemonnier, Johanna Lepeule, Wenche Nystad, Christian Magnus Page, Sviatlana Panasevich, Dirkje Postma, Rémy Slama, Jordi Sunyer, Cilla Söderhäll, Jin Yao, Stephanie J. London, Göran Pershagen, Gerard H. Koppelman, Erik Melén
Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
published pages: , ISSN: 0091-6765, DOI: 10.1289/EHP36
Environmental Health Perspectives 125/1 2019-06-07

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The information about "EMBRYOANDLATERHEALTH" are provided by the European Opendata Portal: CORDIS opendata.

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