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MediHealth SIGNED

Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources

Total Cost €

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EC-Contrib. €

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Partnership

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 MediHealth project word cloud

Explore the words cloud of the MediHealth project. It provides you a very rough idea of what is the project "MediHealth" about.

scheme    plant    countries    silico    benefits    innovation    isolation    core    multidisciplinary    stage    nutraceuticals    pharmacological    profiling    global    base    vivo    sources    enterprises    interests    competences    complimentary    healthy    model    extended    vitro    orientation    dietary    comprise    special    embrace    metabolites    environments    mediterranean    successful    mice    complementary    cell    medihealth    subjected    public    levels    metabolism    seconded    efficient    natural    active    transferred    evaluation    skills    lasting    food    generating    expertise    mutual    assays    innovative    sectors    models    balanced    performed    constituents    tc    synergies    analytical    carry    discovery    synthesis    platform    supplements    scientific    plants    optimization    identification    industry    training    introduce    universities    diet    techniques    ageing    agents    rationally    interactive    bioactive    area    researcher    flies    secondments    aspires    academia    valuable    considerably   

Project "MediHealth" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAET INNSBRUCK 

Organization address
address: INNRAIN 52
city: INNSBRUCK
postcode: 6020
website: http://www.uibk.ac.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Project website http://medihealth.eu/
 Total cost 1˙224˙000 €
 EC max contribution 1˙224˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2015
 Funding Scheme MSCA-RISE
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAET INNSBRUCK AT (INNSBRUCK) coordinator 288˙000.00
2    ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON EL (ATHINA) participant 292˙500.00
3    UNIVERSITE DE GENEVE CH (GENEVE) participant 153˙000.00
4    UNIVERSITEIT ANTWERPEN BE (ANTWERPEN) participant 130˙500.00
5    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 103˙500.00
6    GALENICA FARMAKEFTIKI VIDMICHANIA ANONYMOS ETAIRIA EL (KIFISIA) participant 90˙000.00
7    ROUSSELET CENTRIFUGATION SA FR (ANNONAY) participant 90˙000.00
8    BIONORICA RESEARCH GMBH AT (INNSBRUCK) participant 58˙500.00
9    VIVACELL BIOTECHNOLOGY GMBH DE (DENZLINGEN) participant 18˙000.00
10    FACULTE DES SCIENCES DE SFAX TN (SFAX) partner 0.00
11    TRUONG DAI HOC Y DUOC TP.HCM VN (HO CHI MINH CITY) partner 0.00
12    TSHWANE UNIVERSITY OF TECHNOLOGY ZA (PRETORIA) partner 0.00
13    UNIVERSIDAD CATOLICA DEL NORTE CL (ANTOFAGASTA) partner 0.00

Map

 Project objective

The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved through an extended and well-balanced scheme of researcher’s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing complementary expertise will be the base of this proposal. Plants from the Mediterranean diet and food plants from TC will be rationally selected and will be subjected to an integrated, interactive and comprehensive platform including in silico, in vitro (advanced cell-based assays), in vivo (flies and mice models) & metabolism assessment. Advanced analytical techniques will embrace the pharmacological evaluation process for the efficient isolation and identification of bioactive plant constituents. Pharmacological profiling of bioactive natural products as well as identification and synthesis of their metabolites will be carried out. Finally, to carry to the stage of development innovative products in the area of nutraceuticals/dietary supplements process-optimization studies will be performed. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). MediHealth aspires to comprise a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia generating innovation potential at the European and global levels.

 Deliverables

List of deliverables.
Establishment of a website Websites, patent fillings, videos etc. 2020-02-12 09:16:01

Take a look to the deliverables list in detail:  detailed list of MediHealth deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Waltenberger B., Adamopoulos N., Allouche N., Fiebich B., Halabalaki M., Heinke R., Jansen-Dürr P., Kesternich V., Pieters L., Queiroz E.F., Schönbichler S., Schwaiger S., Skaltsounis A.-L., Tran H., Trougakos I.P., Viljoen A., Wolfender J.-L., Wolfrum C., Xynos N., Stuppner H.
Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources - the MediHealth project
published pages: , ISSN: , DOI:
PHYTO Valley - First Austrian Summit on Natural Products 2020-02-13
2019 B Waltenberger, N Adamopoulos, N Allouche, B Fiebich, M Halabalaki, P Jansen-Dürr, V Kesternich, L Pieters, S Schönbichler, LA Skaltsounis, H Tran, IP Trougakos, A Viljoen, J-L Wolfender, C Wolfrum, N Xynos, H Stuppner
MediHealth – an interdisciplinary and international research and innovation staff exchange project to identify novel natural products for healthy ageing
published pages: 1572, ISSN: , DOI: 10.1055/s-0039-3400404
67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP 85(18) 2020-02-13
2018 Nora S. Engels, Birgit Waltenberger, Barbara Michalak, Loi Huynh, Hung Tran, Anna K. Kiss, Hermann Stuppner
Inhibition of Pro-Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves
published pages: e1800269, ISSN: 1612-1872, DOI: 10.1002/cbdv.201800269
Chemistry & Biodiversity 15/11 2020-02-13
2018 Dimitrios Stagos, Dimitrios Balabanos, Salomi Savva, Zoi Skaperda, Alexandros Priftis, Efthalia Kerasioti, Eleni V. Mikropoulou, Konstantina Vougogiannopoulou, Sofia Mitakou, Maria Halabalaki, Demetrios Kouretas
Extracts from the Mediterranean Food Plants Carthamus lanatus , Cichorium intybus , and Cichorium spinosum Enhanced GSH Levels and Increased Nrf2 Expression in Human Endothelial Cells
published pages: 1-14, ISSN: 1942-0900, DOI: 10.1155/2018/6594101
Oxidative Medicine and Cellular Longevity 2018 2020-02-13
2018 Sophia Wedel, Maria Manola, Maria Cavinato, Ioannis Trougakos, Pidder Jansen-Dürr
Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing
published pages: 1219, ISSN: 1420-3049, DOI: 10.3390/molecules23051219
Molecules 23/5 2020-02-13
2018 Eleni Mikropoulou, Konstantina Vougogiannopoulou, Eleftherios Kalpoutzakis, Aimilia Sklirou, Zoi Skaperda, Joëlle Houriet, Jean-Luc Wolfender, Ioannis Trougakos, Dimitrios Kouretas, Maria Halabalaki, Sofia Mitakou
Phytochemical Composition of the Decoctions of Greek Edible Greens (Chórta) and Evaluation of Antioxidant and Cytotoxic Properties
published pages: 1541, ISSN: 1420-3049, DOI: 10.3390/molecules23071541
Molecules 23/7 2020-02-13
2018 Waltenberger, Birgit; Halabalaki, Maria; Schwaiger, Stefan; Adamopoulos, Nicolas; Allouche, Noureddine; Fiebich, Bernd L; Hermans, Nina; Jansen-Dürr, Pidder; Kesternich, Victor; Pieters, Luc; Schönbichler, Stefan; Skaltsounis, Alexios-Leandros; Tran, Hung; Trougakos, Ioannis P; Viljoen, Alvaro; Wolfender, Jean-Luc; Wolfrum, Christian; Xynos, Nikos; Stuppner, Hermann
Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources—The MediHealth Project
published pages: 1097, ISSN: 1420-3049, DOI: 10.3929/ethz-b-000277279
Molecules 23(5) 2020-02-13
2017 Sentiljana Gumeni, Zoi Evangelakou, Vassilis Gorgoulis, Ioannis Trougakos
Proteome Stability as a Key Factor of Genome Integrity
published pages: 2036, ISSN: 1422-0067, DOI: 10.3390/ijms18102036
International Journal of Molecular Sciences 18/10 2020-02-13
2019 EV Mikropoulou, Z Evangelakou, M Manola, S Gumeni, IP Trougakos, LA Skaltsounis, M Halabalaki
A holistic UPLC-HRMS-based approach exploring the phytochemistry, bioactivity and metabolome impact of Cichorium spinosum’ s decoction in Drosophila melanogaster
published pages: , ISSN: , DOI: 10.1055/s-0039-3399823
67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP 2020-02-13
2019 ME Sakavitsi, A Breynaert, A Angelis, L Pieters, N Hermans, S Mitakou, M Halabalaki
Simulating Human Gastrointestinal and colonic biotransformation pathways through and in vitro assay reveals insight on hydroxytyrosol and oleuropein metabolism
published pages: , ISSN: , DOI:
Young Researchers Workshop GA 2019 2020-02-13
2016 Vincent Brieudes, Apostolis Angelis, Konstantina Vougogiannopoulou, Harris Pratsinis, Dimitris Kletsas, Sofia Mitakou, Maria Halabalaki, Leandros Skaltsounis
Phytochemical Analysis and Antioxidant Potential of the Phytonutrient-Rich Decoction of Cichorium spinosum and C. intybus
published pages: 1070-1078, ISSN: 0032-0943, DOI: 10.1055/s-0042-107472
Planta Medica 82/11/12 2020-02-12
2017 Ioannis P. Trougakos
Proteostasis network deregulation as a main molecular link of ageing and carcinogenesis
published pages: , ISSN: , DOI:
39th ANNUAL CONFERENCE OF THE HELLENIC SOCIETY FOR BIOLOGICAL SCIENCES Proceedings Lecture 2020-02-12
2017 ME Sakavitsi, Z Evangelakou, A Faúndez Catherine, G Lemus Belen Ringele, A Argyropoulou, V Kesternich, I Trougakos, M Halabalaki, A Skaltsounis Leandros
Phytochemical investigation of the Chilean berries Aristotelia chilensis and Ugni molinae. Evaluation of their anti-ageing effects employing a Drosophila model.
published pages: , ISSN: , DOI: 10.1055/s-0037-1608278
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017) 2020-02-12
2018 Eleni N. Tsakiri, Sentiljana Gumeni, Kalliopi K. Iliaki, Dimitra Benaki, Konstantinos Vougas, Gerasimos P. Sykiotis, Vassilis G. Gorgoulis, Emmanuel Mikros, Luca Scorrano and Ioannis P. Trougakos
Nrf2 as a main hub in the wiring of proteostatic, mitostatic and metabolic pathways
published pages: , ISSN: , DOI:
COST Action BM1307 PROTEOSTASIS, Proteostatic Mechanisms in Health & Disease Proceedings Oral Presentation 2020-02-12
2017 Ioannis P. Trougakos
Nrf2 as a central hub in the wiring of proteostatic, mitostatic and metabolic pathways
published pages: 12, ISSN: , DOI:
68th Panhellenic Congress of the Greek Biochemical and Molecular Biology Society Proceedings Lecture 14 2020-02-12
2017 N Mncwangi, B Waltenberger, G Baraldo, P Jansen-Dürr, A Viljoen, H Stuppner
Sclerocarya birrea cortex ethanolic extract – Chemical characterisation and NOX4 inhibition (anti-ageing property)
published pages: , ISSN: , DOI: 10.1055/s-0037-1608258
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017) 2020-02-12
2017 Maria-Eleni Sakavitsi, Zoi Evangelakou, Gabriela Belen Lemus Ringele, Amal Ghorbel, Aikaterini Argyropoulou, Victor Kesternich, Noureddine Allouche, Ioannis Trougakos, Maria Halabalaki, Leandros Skaltsounis
EXPLORATION OF DIETARY PLANTS FROM WORLDWIDE BIODIVERSITY AIMING THE DISCOVERY OF ACTIVE AGENTS WITH ANTI-AGEING EFFECTS
published pages: 20, ISSN: , DOI:
Proceedings PP192 2020-02-12

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