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EVOluTION SIGNED

European Vascular Interventions and Therapeutic Innovation Network

Total Cost €

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EC-Contrib. €

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Partnership

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 EVOluTION project word cloud

Explore the words cloud of the EVOluTION project. It provides you a very rough idea of what is the project "EVOluTION" about.

chemistry    communication    educational    pharma    population    biotech    transferable    pioneering    platform    sme    engagement    cutting    local    processes    integrating    young    angles    pharmacology    body    aligned    guarantee    societies    knowledge    vascular    formed    protective    gain    scientific    nutraceuticals    societal    conducive    structure    education    tools    skills    answer    vasculature    chronic    boosting    mediators    therapies    patent    interdisciplinary    view    triangle    dietary    ageing    companies    multidisciplinary    innovative    specialized    scientists    trade    policy    countries    lab    protection    resolution    mechanisms    tissue    medical    secondments    natural    focussed    diseases    maximally    valuable    visits    firm    therapeutic    boost    leaders    trained    cross    business    western    training    computational    industrial    academic    strategies    metabolic    expertise    creation    questions    endogenous    maker    yield    provides    11    entrepreneurship    evolution    detection    network    science    prevention    exploited   

Project "EVOluTION" data sheet

The following table provides information about the project.

Coordinator
QUEEN MARY UNIVERSITY OF LONDON 

Organization address
address: 327 MILE END ROAD
city: LONDON
postcode: E1 4NS
website: http://www.qmul.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://www.qmul.ac.uk/evolution/
 Total cost 2˙887˙041 €
 EC max contribution 2˙887˙041 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-04-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    QUEEN MARY UNIVERSITY OF LONDON UK (LONDON) coordinator 819˙863.00
2    UNIVERSITEIT MAASTRICHT NL (MAASTRICHT) participant 766˙122.00
3    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 498˙432.00
4    LIFEARC UK (LONDON) participant 273˙287.00
5    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) participant 265˙674.00
6    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 263˙659.00
7    Genomics England Limited UK (London) partner 0.00
8    Kilburn & Strode UK (London) partner 0.00
9    MosaMedix NL (Susteren) partner 0.00
10    QUINTILES LIMITED UK (READING) partner 0.00
11    THE ROYAL SOCIETY OF CHEMISTRY UK (CAMBRIDGE) partner 0.00
12    UCB PHARMA SA BE (BRUXELLES) partner 0.00
13    William Harvey Research Limited UK (London) partner 0.00

Map

 Project objective

EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully aligned with the knowledge triangle (business, research and higher education) platform being developed at the EU level, EVOluTION-trained young scientists will gain valuable knowledge and multidisciplinary skills: only interdisciplinary and cross-cutting research can lead to novel therapeutic tools and scientific angles to address these challenging medical, societal and industrial issues. EVOluTION provides a conducive structure by bringing 5 leading academic institutions and 1 SME, together with 6 Pharma and biotech companies, 1 Policy-maker, and 1 Patent & Trade firm as Partner Organisations, from 6 EU countries. The science of EVOluTION evolves around the innovative concept of boosting natural protective mechanisms operating in our body, focusing on the vasculature, to answer 3 key questions: Can we exploit mediators and targets of endogenous tissue protection? Can we exploit these pathways to yield innovative therapeutic strategies? Can dietary approaches boost these endogenous protective processes? The Network Partners guarantee delivery of training through knowledge creation, knowledge exploitation and knowledge communication. Scientific and educational expertise of the partners, leaders in areas like computational chemistry, nutraceuticals, resolution pharmacology and vascular therapies will be maximally exploited. The EVOluTION training platform is based on state-of-the-art lab-based and network-wide and local training activities, including secondments and scientific visits and specialized transferable skills focussed in entrepreneurship and societal engagement.

 Deliverables

List of deliverables.
EVOluTION Web site Websites, patent fillings, videos etc. 2019-07-10 10:45:12
Guidelines for recruitment strategy Documents, reports 2019-07-10 10:45:12

Take a look to the deliverables list in detail:  detailed list of EVOluTION deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Silvia Oggero, Shani Austin-Williams, Lucy Victoria Norling
The Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair
published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2019.01479
Frontiers in Pharmacology 10 2020-02-19
2019 Ploingarm Petsophonsakul, Malgorzata Furmanik, Rachael Forsythe, Marc Dweck, Geert Willem Schurink, Ehsan Natour, Chris Reutelingsperger, Michael Jacobs, Barend Mees, Leon Schurgers
Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation
published pages: 1351-1368, ISSN: 1079-5642, DOI: 10.1161/atvbaha.119.312787
Arteriosclerosis, Thrombosis, and Vascular Biology 39/7 2020-01-29
2019 Chiara Moretti, Zhengbing Zhuge, Gensheng Zhang, Sarah McCann Haworth, Luciano L. Paulo, Drielle D. Guimarães, Josiane C. Cruz, Marcelo F. Montenegro, Isabel Cordero-Herrera, Valdir A. Braga, Eddie Weitzberg, Mattias Carlström, Jon O. Lundberg
The obligatory role of host microbiota in bioactivation of dietary nitrate
published pages: 342-348, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.10.003
Free Radical Biology and Medicine 145 2019-10-29
2018 Monica de Gaetano, Caitriona McEvoy, Darrell Andrews, Antonino Cacace, Jonathan Hunter, Eoin Brennan, Catherine Godson
Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications
published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2018.01488
Frontiers in Pharmacology 9 2019-10-15
2019 Isabel Cordero-Herrera, Mikael Kozyra, Zhengbing Zhuge, Sarah McCann Haworth, Chiara Moretti, Maria Peleli, Mayara Caldeira-Dias, Arghavan Jahandideh, Han Huirong, Josiane de Campos Cruz, Andrei L. Kleschyov, Marcelo F. Montenegro, Magnus Ingelman-Sundberg, Eddie Weitzberg, Jon O. Lundberg, Mattias Carlstrom
AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis
published pages: 217-226, ISSN: 0027-8424, DOI: 10.1073/pnas.1809406115
Proceedings of the National Academy of Sciences 116/1 2019-09-02
2019 Marilena Crescente, Laura Menke, Melissa V Chan, Paul C Armstrong, Timothy D Warner
Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)
published pages: 988-999, ISSN: 0007-1188, DOI: 10.1111/bph.14196
British Journal of Pharmacology 176/8 2019-09-02
2019 Maurice Halder, Ploingarm Petsophonsakul, Asim Akbulut, Angelina Pavlic, Frode Bohan, Eric Anderson, Katarzyna Maresz, Rafael Kramann, Leon Schurgers
Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease
published pages: 896, ISSN: 1422-0067, DOI: 10.3390/ijms20040896
International Journal of Molecular Sciences 20/4 2019-09-04
2019 Bartolo Ferraro, Giovanna Leoni, Rabea Hinkel, Steffen Ormanns, Nicole Paulin, Almudena Ortega-Gomez, Joana R. Viola, Renske de Jong, Dario Bongiovanni, Tarik Bozoglu, Sanne L. Maas, Michele D’Amico, Thorsten Kessler, Tanja Zeller, Michael Hristov, Chris Reutelingsperger, Hendrik B. Sager, Yvonne Döring, Matthias Nahrendorf, Christian Kupatt, Oliver Soehnlein
Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair
published pages: 2990-3002, ISSN: 0735-1097, DOI: 10.1016/j.jacc.2019.03.503
Journal of the American College of Cardiology 73/23 2019-09-02
2018 Nicole Paulin, Joana R. Viola, Sanne L. Maas, Renske de Jong, Teresa Fernandes-Alnemri, Christian Weber, Maik Drechsler, Yvonne Döring, Oliver Soehnlein
Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability
published pages: 321-323, ISSN: 0009-7322, DOI: 10.1161/circulationaha.117.033098
Circulation 138/3 2019-09-02
2017 Jan Nagenborg, Pieter Goossens, Erik A.L. Biessen, Marjo M.P.C. Donners
Heterogeneity of atherosclerotic plaque macrophage origin, phenotype and functions: Implications for treatment
published pages: 14-24, ISSN: 0014-2999, DOI: 10.1016/j.ejphar.2017.10.005
European Journal of Pharmacology 816 2019-09-02
2017 Eoin P. Brennan, Antonino Cacace, Catherine Godson
Specialized pro-resolving mediators in renal fibrosis
published pages: 102-113, ISSN: 0098-2997, DOI: 10.1016/j.mam.2017.05.001
Molecular Aspects of Medicine 58 2019-09-02
2018 Joana Viola, Patricia Lemnitzer, Nicole Paulin, Maik Drechsler, Maliheh Nazari-Jahantigh, Sanne Maas, Renske De Jong, Janine Winter, Andreas Schober, Christian Weber, Kamran Atabai, Oliver Soehnlein
Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage
published pages: 1340-1342, ISSN: 0340-6245, DOI: 10.1055/s-0038-1649522
Thrombosis and Haemostasis 118/07 2019-09-02
2018 Sanne L. Maas, Oliver Soehnlein, Joana R. Viola
Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.02739
Frontiers in Immunology 9 2019-09-02
2019 Monica de Gaetano, Eibhlín Butler, Kevin Gahan, Andrea Zanetti, Mariam Marai, Jianmin Chen, Antonino Cacace, Emily Hams, Catherine Maingot, Alisha McLoughlin, Eoin Brennan, Xavier Leroy, Christine E. Loscher, Padraic Fallon, Mauro Perretti, Catherine Godson, Patrick J. Guiry
Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms)
published pages: 80-108, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.10.049
European Journal of Medicinal Chemistry 162 2019-07-10

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