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IonoChem

IonoChem: A new and highly efficient cross membrane drug delivery strategy

Total Cost €

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EC-Contrib. €

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Partnership

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 IonoChem project word cloud

Explore the words cloud of the IonoChem project. It provides you a very rough idea of what is the project "IonoChem" about.

refinement    amounts    fee    turn    systemic    gmp    customers    plan    vioxx    administered    customer    techniques    drug    lipophilization    eg    model    lipohilic    elaboration    us    hydrophobic    quantities    market    ionochem    perform    proprietary    intracellular    membrane    tails    global    initial    manufacturers    licensing    search    qualification    suitable    technologies    2013    adding    establishment    segments    rnai    service    ups    contact    annual    times    designed    company    sufficient    sales    types    easily    withdrawn    ionovation    dna    biological    solution    inside    introduction    11    therapeutics    enter    one    toxic    manufacturer    line    preclinical    valued    head    clients    billion    membranes    classes    vs    ratio    platform    quarters    business    facilities    rna    pricing    many    patient    experimental    contract    worth    pass    drugs    cells    upscaling    molecules    molecule    tail    cell    151    nature    setting   

Project "IonoChem" data sheet

The following table provides information about the project.

Coordinator
IONOVATION GMBH 

Organization address
address: WESTERBREITE 7
city: OSNABRUCK
postcode: 49084
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.ionovation.com/index.php/ionochem
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2016-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IONOVATION GMBH DE (OSNABRUCK) coordinator 50˙000.00

Map

 Project objective

Many drugs are designed to target molecules inside cells. Due to the hydrophobic nature of the cell membranes however not all types of drugs can enter the cells in sufficient quantities. Thus large amounts of drug need to be administered which can lead to highly toxic systemic effects for the patient. Furthermore, new classes of therapeutics such as RNA- and DNA-based drugs require advanced delivery techniques to reach their intracellular targets. Ionovation’s proprietary IonoChem technology will provide a novel and highly effective solution to this problem by adding lipohilic “tails” directly to drug molecules at a one-on-one ratio. These “tails” allow drugs to easily pass through the cell membrane. As part of a service offer Ionovation will work with clients to identify the most effective tail for a particular molecule, and will also perform the lipophilization. The IonoChem platform will enable Ionovation GmbH (a manufacturer of experimental set-ups for the analysis of biological membranes) to enter the market for drug delivery technologies, thus creating a new line of business for the company. IonoChem will target the market for drug delivery systems, which was valued at US$151 billion in 2013. Market segments for initial introduction of the technology include RNAi drug delivery (a market worth US $11,7 billion in 2013) and drugs withdrawn from the market (eg Vioxx with 2.5 billion US $ annual global sales). Objectives of the phase I project include analysis of customer needs (pricing, expected turn-around times etc.), refinement of business model (licensing/fee for use model for contract manufacturers vs. service offer with production facilities at Ionovation’s head quarters); search for a suitable contract manufacturer for the phase II activities and the elaboration of a business plan. Phase II objectives include upscaling of the production under GMP conditions, establishment of contact to customers and the qualification of IonoChem in a preclinical setting.

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The information about "IONOCHEM" are provided by the European Opendata Portal: CORDIS opendata.

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