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IonoChem

IonoChem: A new and highly efficient cross membrane drug delivery strategy

Total Cost €

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EC-Contrib. €

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Partnership

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 IonoChem project word cloud

Explore the words cloud of the IonoChem project. It provides you a very rough idea of what is the project "IonoChem" about.

technologies    inside    withdrawn    refinement    perform    qualification    classes    elaboration    ups    many    quantities    11    business    initial    enter    upscaling    drugs    designed    eg    dna    plan    experimental    establishment    head    search    licensing    one    nature    therapeutics    systemic    times    contact    administered    amounts    turn    types    billion    easily    vs    151    cell    ionovation    company    pricing    annual    sales    molecules    lipophilization    us    intracellular    valued    toxic    market    vioxx    quarters    membranes    manufacturer    introduction    molecule    proprietary    worth    lipohilic    platform    line    service    global    tail    pass    2013    hydrophobic    suitable    tails    setting    customers    ratio    facilities    membrane    rnai    segments    rna    preclinical    techniques    cells    sufficient    fee    gmp    manufacturers    drug    biological    contract    adding    model    customer    patient    ionochem    solution    clients   

Project "IonoChem" data sheet

The following table provides information about the project.

Coordinator
IONOVATION GMBH 

Organization address
address: WESTERBREITE 7
city: OSNABRUCK
postcode: 49084
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.ionovation.com/index.php/ionochem
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2016-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IONOVATION GMBH DE (OSNABRUCK) coordinator 50˙000.00

Map

 Project objective

Many drugs are designed to target molecules inside cells. Due to the hydrophobic nature of the cell membranes however not all types of drugs can enter the cells in sufficient quantities. Thus large amounts of drug need to be administered which can lead to highly toxic systemic effects for the patient. Furthermore, new classes of therapeutics such as RNA- and DNA-based drugs require advanced delivery techniques to reach their intracellular targets. Ionovation’s proprietary IonoChem technology will provide a novel and highly effective solution to this problem by adding lipohilic “tails” directly to drug molecules at a one-on-one ratio. These “tails” allow drugs to easily pass through the cell membrane. As part of a service offer Ionovation will work with clients to identify the most effective tail for a particular molecule, and will also perform the lipophilization. The IonoChem platform will enable Ionovation GmbH (a manufacturer of experimental set-ups for the analysis of biological membranes) to enter the market for drug delivery technologies, thus creating a new line of business for the company. IonoChem will target the market for drug delivery systems, which was valued at US$151 billion in 2013. Market segments for initial introduction of the technology include RNAi drug delivery (a market worth US $11,7 billion in 2013) and drugs withdrawn from the market (eg Vioxx with 2.5 billion US $ annual global sales). Objectives of the phase I project include analysis of customer needs (pricing, expected turn-around times etc.), refinement of business model (licensing/fee for use model for contract manufacturers vs. service offer with production facilities at Ionovation’s head quarters); search for a suitable contract manufacturer for the phase II activities and the elaboration of a business plan. Phase II objectives include upscaling of the production under GMP conditions, establishment of contact to customers and the qualification of IonoChem in a preclinical setting.

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The information about "IONOCHEM" are provided by the European Opendata Portal: CORDIS opendata.

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