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Opendata, web and dolomites

RUBICON SIGNED

Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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Outcomes and
results

RUBICON project word cloud

Explore the words cloud of the RUBICON project. It provides you a very rough idea of what is the project "RUBICON" about.

targetable cell biochemists excellent instruments respective er disorders intracellular countries laboratories diverse circadian pathophysiology tissues recognised secondments mechanisms consolidate global focussed components scientists commonalities networking class core bone human webinars communication biologists groups courses stress cartilage fertilise network matrix solid clock staff genetic meetings arena determinants biochemical reinforce biomechanical multidisciplinary pathogenesis clinicians internationally technologies secure exchange additional signalling basis animal equipped innovation connective create facilities oxidative extensive scientific data geneticists training morphologists skills laboratory participating ethics rubicon underlying soluble fundamental interdisciplinary tendons molecular cross young extracellular external homeostasis tissue attractive

Project "RUBICON" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITA DEGLI STUDI DELL'AQUILA Organization address address: PIAZZA SANTA MARGHERITA 2 city: L AQUILA postcode: 67100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Project website	http://rubicon-network.org/
Total cost	877˙500 €
EC max contribution	607˙500 € (69%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITA DEGLI STUDI DELL'AQUILA UNIVERSITA DEGLI STUDI DELL'AQUILA Organization address address: PIAZZA SANTA MARGHERITA 2 city: L AQUILA postcode: 67100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (L AQUILA)	coordinator	171˙000.00
2	THE UNIVERSITY OF MANCHESTER THE UNIVERSITY OF MANCHESTER Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL website: www.manchester.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (MANCHESTER)	participant	144˙000.00
3	REGION HOVEDSTADEN REGION HOVEDSTADEN Organization address address: KONGENS VAENGE 2 city: HILLEROD postcode: 3400 website: www.regionh.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (HILLEROD)	participant	108˙000.00
4	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	participant	94˙500.00
5	UNIVERSITY OF NEWCASTLE UPON TYNE UNIVERSITY OF NEWCASTLE UPON TYNE Organization address address: KINGS GATE city: NEWCASTLE UPON TYNE postcode: NE1 7RU website: http://www.ncl.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NEWCASTLE UPON TYNE)	participant	90˙000.00
6	ANNA UNIVERSITY CHENNAI ANNA UNIVERSITY CHENNAI Organization address address: Sardar Patel Road city: CHENNAI postcode: 600025 website: www.annauniv.edu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IN (CHENNAI)	partner	0.00
7	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Organization address address: ONE GUSTAVE L LEVY PLACE BOX 1075 city: NEW YORK postcode: 10029 6574 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (NEW YORK)	partner	0.00
8	MURDOCH CHILDRENS RESEARCH INSTITUTE MURDOCH CHILDRENS RESEARCH INSTITUTE Organization address address: FLEMINGTON ROAD RCH city: PARKVILLE postcode: 3052 website: www.mcri.edu.au contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AU (PARKVILLE)	partner	0.00
9	THE UNIVERSITY OF HONG KONG THE UNIVERSITY OF HONG KONG Organization address address: Pokfulam Road city: Pokfulam postcode: n.a. website: www.hku.hk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HK (Pokfulam)	partner	0.00
10	UNIVERSITY OF CAPE TOWN UNIVERSITY OF CAPE TOWN Organization address address: PRIVATE BAG X3 city: RONDEBOSCH postcode: 7701 website: www.uct.ac.za contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ZA (RONDEBOSCH)	partner	0.00

Map

Project objective

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field. Researchers involved in secondments between RUBICON participants will investigate genetic determinants, circadian clock, extracellular matrix components, soluble biochemical factors and intracellular signalling pathways, ER stress and oxidative components involved in connective tissue homeostasis and pathogenesis. Extensive training during secondments will include new technologies and innovation, study design, interdisciplinary laboratory research, data analysis, research management, ethics in animal and human studies, and development of scientific and communication skills. All participating laboratories will ensure attractive working conditions in excellent and internationally recognised institutions, equipped with state-of-the-art instruments and excellent core facilities. Webinars, courses and meetings will provide additional opportunities for training and networking, also be open to external participants. RUBICON is a unique interdisciplinary network including cell biologists, molecular biologists, animal biologists, morphologists, geneticists, biochemists and clinicians who will cross-fertilise their respective research fields. The long-term goal of RUBICON is to consolidate a class of young scientists to secure future developments in the connective tissue arena and create a solid basis for further collaboration in this field.

Deliverables

List of deliverables.
Press releases	Websites, patent fillings, videos etc.	2020-02-20 16:54:37
Reports on RUBICON training events and webinars	Documents, reports	2020-02-20 16:54:37
Info-packs describing arrangements for receiving staff exchanges	Documents, reports	2020-02-20 16:54:37
Project website	Websites, patent fillings, videos etc.	2020-02-20 16:54:37
Communication and media protocol	Other	2020-02-20 16:54:37

Take a look to the deliverables list in detail: detailed list of RUBICON deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Antonio Maurizi, Mattia Capulli, Annabel Curle, Rajvi Patel, Argia Ucci, Juliana Alves CÃ´rtes, Harriet Oxford, Shireen R. LamandÃ©, John F. Bateman, Nadia Rucci, Anna Teti Extra-skeletal manifestations in mice affected by Clcn7-dependent autosomal dominant osteopetrosis type 2 clinical and therapeutic implications published pages: , ISSN: 2095-6231, DOI: 10.1038/s41413-019-0055-x	Bone Research 7/1	2020-03-11
2019	Peter Hung Thanh Tran The mechanisms behind the development of tendinopathy: Early structural, inflammatory, nociceptive and clinical changes published pages: , ISSN: , DOI:		2020-02-20
2017	Maurizi A, Capulli M, Patel R, Rucci N, Teti. CLCN7-dependent Autosomal Dominant Osteopetrosis type 2 (ADO2): more than a bone disease. published pages: , ISSN: 0884-0431, DOI: 10.1002/jbmr.v32.S1	Journal of Bone and Mineral Research 32/S1	2020-02-20
2017	Vimal Veeriah, University of L\'Aquila, Mattia Capulli, University of L\'Aquila, Angelo Zanniti Interleukin 1Î² (IL1Î²), Nitric Oxide Synthase 2 (NOS2), Lipocalin 2 (LCN2) and Vascular Endothelial Growth Factor (VEGF) Orchestrate the Coupled Mechanoresponse of Skeletal Angiogenesis and Osteogenesis published pages: , ISSN: 0884-0431, DOI: 10.1002/jbmr.v31.S1	Journal of Bone and Mineral Research 31/S1	2020-02-20
2017	Antonio Maurizi, Nadia Rucci, Tina Schleicher, Yadhu Kumar, Anna Teti, Mattia Capulli,. Transcriptomic Analysis of Osteoclasts from Autosomal Dominant Osteopetrosis type2 (ADO2) Mice harboring the G213R Mutation of the Chloride-Proton Antiporter type 7 (ClC7) published pages: , ISSN: 1523-4681, DOI: 10.1002/jbmr.v32.S1/issuetoc	Journal of Bone and Mineral Research 32/S1	2020-02-20
2017	Maurizi A, Capulli M, Patel R, Rucci N, Teti. A deep phenotyping of autosomal dominant osteopetrosis type 2 (ADO2) mouse model revealed multiorgan dysfunctions. published pages: , ISSN: , DOI:	International Conference on Children Bone Health held in WÃ¼rzburg, Germany, on June 10-13, 2017.	2020-02-20
2018	Vimal Veeriah, Riccardo Paone, Suvro Chatterjee, Anna Teti, Mattia Capulli Osteoblasts Regulate Angiogenesis in Response to Mechanical Unloading published pages: , ISSN: 0171-967X, DOI: 10.1007/s00223-018-0496-z	Calcified Tissue International Nov 21	2020-02-20
2016	Vimal Veeriah, Angelo Zanniti, Riccardo Paone, Suvro Chatterjee, Nadia Rucci, Anna Teti, Mattia Capulli Interleukin-1Î², lipocalin 2 and nitric oxide synthase 2 are mechano-responsive mediators of mouse and human endothelial cell-osteoblast crosstalk published pages: 6:29880, ISSN: 2045-2322, DOI: 10.1038/srep29880	Scientific Reports 6/1	2020-02-20
2017	Anna Teti, Michael J. Econs Osteopetroses, emphasizing potential approaches to treatment published pages: pii: S8756-3282(, ISSN: 8756-3282, DOI: 10.1016/j.bone.2017.02.002	Bone 102	2020-02-20
2018	John F. Bateman, Lisa Sampurno, Antonio Maurizi, Shireen R. LamandÃ©, Natalie A. Sims, Tegan L. Cheng, Aaron Schindeler, David G. Little Effect of rapamycin on bone mass and strength in the Î±2(I)-G610C mouse model of osteogenesis imperfecta published pages: , ISSN: 1582-1838, DOI: 10.1111/jcmm.14072	Journal of Cellular and Molecular Medicine 2018;00:1â€11	2020-02-20

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The information about "RUBICON" are provided by the European Opendata Portal: CORDIS opendata.

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