Explore the words cloud of the HoloVision project. It provides you a very rough idea of what is the project "HoloVision" about.
The following table provides information about the project.
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
|Coordinator Country||Israel [IL]|
|Total cost||2˙624˙517 €|
|EC max contribution||2˙624˙517 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2016-01-01 to 2020-12-31|
Take a look of project's partnership.
|1||TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY||IL (HAIFA)||coordinator||2˙624˙517.00|
When natural sensory input is disrupted, as in outer-retinal degenerative diseases, artificial stimulation of surviving nerve cells offers a potential strategy for bypassing compromised neural circuits and substituting sensory perception. Current neuro-stimulation interfaces that use electrical currents from micro-electrode arrays are already being clinically applied for retinal stimulation, but their performance is ultimately limited by current spread and the requirement for physical contact with an implanted device. Future minimally-invasive systems could use light patterns to photo-induce complex yet precise spatio-temporal activity patterns among surviving retinal neurons, with the ultimate potential of restoring vision to a nearly normal level. Here, we will advance, optimize and test in vivo a powerful new strategy for cellular-resolution controlled patterned optogenetic excitation, based on computer-generated holographic optical neural-stimulation (HONS). Regular (one-photon) HONS systems can dynamically address large populations of optogenetically-transduced retinal ganglion cells with single-cell resolution, while related multiphoton HONS systems can extend these capabilities to three-dimensional cortical tissue (relevant to many research applications). A series of in vivo experiments will resolve basic questions regarding the efficacy of these approaches by directly examining the retinal and cortical responses to structured holographic photo-stimulation, and test novel strategies for improving it. Finally, as a major step towards clinical translation of this technology, we will design and evaluate (in blind sheep and sighted individuals) a human-scale prototype. Overall, by combining both basic and translational research, this study will advance novel optical neuro-technologies with potential impact on multiple scientific and clinical applications. Specifically, it will tackle the major engineering requirements and constraints towards the development of a
|year||authors and title||journal||last update|
Ronald W. Boutte, Sam Merlin, Guy Yona, Brandon Griffiths, Alessandra Angelucci, Itamar Kahn, Shy Shoham, Steve Blair
Utah optrode array customization using stereotactic brain atlases and 3-D CAD modeling for optogenetic neocortical interrogation in small rodents and nonhuman primates
published pages: 41502, ISSN: 2329-423X, DOI: 10.1117/1.NPh.4.4.041502
Tal Aharoni, Shy Shoham
Phase-controlled, speckle-free holographic projection with applications in precision optogenetics
published pages: 1, ISSN: 2329-423X, DOI: 10.1117/1.NPh.5.2.025004
Anat Marom, Erez Shor, Shulamit Levenberg, Shy Shoham
Spontaneous Activity Characteristics of 3D â€œOptonetsâ€
published pages: Article 602, ISSN: 1662-453X, DOI: 10.3389/fnins.2016.00602
|Frontiers in Neuroscience 10||2019-06-07|
Michael Plaksin, Eitan Kimmel and Shy Shoham
Thermal transients excite neurons through universalintramembrane mechano-electrical effects
published pages: , ISSN: , DOI: 10.1101/111724
Michael Plaksin, Eitan Kimmel, Shy Shoham
Correspondence: Revisiting the theoretical cell membrane thermal capacitance response
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-00435-5
|Nature Communications 8/1||2019-06-07|
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The information about "HOLOVISION" are provided by the European Opendata Portal: CORDIS opendata.
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