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CoSTREAM SIGNED

Common mechanisms and pathways in Stroke and Alzheimer's disease.

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

CoSTREAM project word cloud

Explore the words cloud of the CoSTREAM project. It provides you a very rough idea of what is the project "CoSTREAM" about.

strategies common epidemiologists ad multidisciplinary incorporating disease vast linking vasculopathy alzheimer crime datasets imaging genomics brain shared neurologists explore longstanding disentangle link network analytical metabolomics fellow record geneticists risk stroke caa radiologists overlapping unravel etiology sequential mr ischemic diverge track pathyphysiological co international pathogenesis technologies travelers big diseases causing either occurrence mechanisms

Project "CoSTREAM" data sheet

The following table provides information about the project.

Coordinator	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://www.costream.eu
Total cost	5˙100˙372 €
EC max contribution	4˙590˙185 € (90%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-PHC-2015-two-stage
Funding Scheme	RIA
Starting year	2015
Duration (year-month-day)	from 2015-12-01 to 2020-11-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	coordinator	1˙098˙750.00
2	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 website: www.uni-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	510˙000.00
3	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	participant	509˙946.00
4	MIMETAS BV MIMETAS BV Organization address address: JH Oortweg 19 city: Leiden postcode: 2333CH website: www.mimetas.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (Leiden)	participant	509˙625.00
5	KING'S COLLEGE LONDON KING'S COLLEGE LONDON Organization address address: STRAND city: LONDON postcode: WC2R 2LS website: www.kcl.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	476˙228.00
6	UNIVERSITEIT LEIDEN UNIVERSITEIT LEIDEN Organization address address: RAPENBURG 70 city: LEIDEN postcode: 2311 EZ website: www.universiteitleiden.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (LEIDEN)	participant	409˙510.00
7	INSTITUT PASTEUR DE LILLE FONDATION INSTITUT PASTEUR DE LILLE FONDATION Organization address address: RUE DU PROFESSEUR CALMETTE 1 city: LILLE postcode: 59019 website: http://www.pasteur-lille.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LILLE)	participant	324˙875.00
8	EIBIR GEMEINNUETZIGE GMBH ZUR FOERDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG EIBIR GEMEINNUETZIGE GMBH ZUR FOERDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG Organization address address: Neutorgasse 9/2 city: VIENNA postcode: 1010 website: www.eibir.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (VIENNA)	participant	323˙750.00
9	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	256˙250.00
10	UNIVERSITE DE BORDEAUX UNIVERSITE DE BORDEAUX Organization address address: PLACE PEY BERLAND 35 city: BORDEAUX postcode: 33000 website: www.nouvelle-univ-bordeaux.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (BORDEAUX)	participant	171˙250.00
11	UNIVERSITE DE GENEVE UNIVERSITE DE GENEVE Organization address address: RUE DU GENERAL DUFOUR 24 city: GENEVE postcode: 1211 website: www.unige.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVE)	participant	0.00

Map

Project objective

Common mechanisms and pathways in Stroke and Alzheimer's disease. It has long been recognized that stroke and (Alzheimer’s Disease) AD often co-occur and have an overlapping pathogenesis. As such, these two diseases are not considered fellow travelers, but rather partners in crime. This multidisciplinary consortium includes epidemiologists, geneticists, radiologists, neurologists with a longstanding track-record on the etiology of stroke and AD. This project aims to improve our understanding of the co-occurrence of stroke and AD. An essential concept of our proposal is that stroke and AD are sequential diseases that have overlapping pathyphysiological mechanisms in addition to shared risk factors. We will particularly focus on these common mechanisms and disentangle when and how these mechanisms diverge into causing either stroke, or AD, or both. Another important concept is that mechanisms under study will not only include the known pathways of ischemic vasculopathy and CAA, but we will explore and unravel novel mechanisms linking stroke and AD. We will do so by exploiting our vast international network in order to link various big datasets and by incorporating novel analytical strategies with emerging technologies in the field of genomics, metabolomics, and brain MR-imaging.

Deliverables

List of deliverables.
WP3 Midterm recruitment report	Documents, reports	2019-10-04 10:18:22

Take a look to the deliverables list in detail: detailed list of CoSTREAM deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Steffen Tiedt, Marco Duering, Christian Barro, Asli Gizem Kaya, Julia Boeck, Felix J. Bode, Matthias Klein, Franziska Dorn, Benno Gesierich, Lars Kellert, Birgit Ertl-Wagner, Michael W. Goertler, Gabor C. Petzold, Jens Kuhle, Frank A. Wollenweber, Nils Peters, Martin Dichgans Serum neurofilament light published pages: e1338-e1347, ISSN: 0028-3878, DOI: 10.1212/wnl.0000000000006282	Neurology 91/14	2019-10-04
2018	Lana Fani, Frank J. Wolters, M. Kamran Ikram, Marco J. Bruno, Albert Hofman, Peter J. Koudstaal, Sarwa Darwish Murad, M. Arfan Ikram Helicobacter pylori and the risk of dementia: A population-based study published pages: 1377-1382, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.05.005	Alzheimer\'s & Dementia 14/10	2019-10-04
2018	Christina S. Dintica, Debora Rizzuto, Anna Marseglia, GrÃ©goria Kalpouzos, Anna-Karin Welmer, Inger WÃ¥rdh, Lars BÃ¤ckman, Weili Xu Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study published pages: 23-30, ISSN: 0197-4580, DOI: 10.1016/j.neurobiolaging.2018.03.003	Neurobiology of Aging 67	2019-10-04
2018	Steffen Tiedt, Martin Dichgans Role of Non-Coding RNAs in Stroke published pages: 3098-3106, ISSN: 0039-2499, DOI: 10.1161/strokeaha.118.021010	Stroke 49/12	2019-10-04
2018	Loes C.A. Rutten-Jacobs, Daniel J. Tozer, Marco Duering, Rainer Malik, Martin Dichgans, Hugh S. Markus, Matthew Traylor Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia published pages: 1340-1347, ISSN: 0039-2499, DOI: 10.1161/STROKEAHA.118.020811	Stroke 49/6	2019-10-04
2018	Steffen Tiedt, Martin Dichgans Role of Non-Coding RNAs in Stroke published pages: 3098-3106, ISSN: 0039-2499, DOI: 10.1161/strokeaha.118.021010	Stroke 49/12	2019-10-04
2018	Lana Fani, Frank J. Wolters, M. Kamran Ikram, Marco J. Bruno, Albert Hofman, Peter J. Koudstaal, Sarwa Darwish Murad, M. Arfan Ikram Helicobacter pylori and the risk of dementia: A population-based study published pages: 1377-1382, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.05.005	Alzheimer\'s & Dementia 14/10	2019-10-04
2018	Federica Prinelli, Debora Rizzuto, Behnaz Shakersain, Ingegerd Johansson, Fulvio Daniele Adorni, Massimo Musicco, Laura Fratiglioni, Weili Xu THE IMPACT OF NUTRIENT PATTERNS ON COGNITIVE DECLINE AMONG SWEDISH OLDER ADULTS: A POPULATION-BASED LONGITUDINAL STUDY published pages: P973-P975, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.06.1308	Alzheimer\'s & Dementia 14/7	2019-10-04
2017	Lori B. Chibnik, Frank J. Wolters, Kristoffer BÃ¤ckman, Alexa Beiser, Claudine Berr, Joshua C. Bis, Eric Boerwinkle, Daniel Bos, Carol Brayne, Jean-Francois Dartigues, Sirwan K. L. Darweesh, Stephanie Debette, Kendra L. Davis-Plourde, Carole Dufouil, Myriam Fornage, Leslie Grasset, Vilmundur Gudnason, Christoforos Hadjichrysanthou, Catherine Helmer, M. Arfan Ikram, M. Kamran Ikram, Silke Kern, Lewis H. Kuller, Lenore Launer, Oscar L. Lopez, Fiona Matthews, Osorio Meirelles, Thomas Mosley, Alison Ower, Bruce M. Psaty, Claudia L. Satizabal, Sudha Seshadri, Ingmar Skoog, Blossom C. M. Stephan, Christophe Tzourio, Reem Waziry, Mei Mei Wong, Anna Zettergren, Albert Hofman Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium published pages: 931-938, ISSN: 0393-2990, DOI: 10.1007/s10654-017-0320-5	European Journal of Epidemiology 32/10	2019-10-04
2018	Juho Tynkkynen, Vincent Chouraki, Sven J. van der Lee, Jussi Hernesniemi, Qiong Yang, Shuo Li, Alexa Beiser, Martin G. Larson, Katri SÃ¤Ã¤ksjÃ¤rvi, Martin J. Shipley, Archana Singh-Manoux, Robert E. Gerszten, Thomas J. Wang, Aki S. Havulinna, Peter WÃ¼rtz, Krista Fischer, Ayse Demirkan, M. Arfan Ikram, Najaf Amin, Terho LehtimÃ¤ki, Mika KÃ¤hÃ¶nen, Markus Perola, Andres Metspalu, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, Ramachandran S. Vasan, Mika KivimÃ¤ki, Cornelia M. van Duijn, Sudha Seshadri, Veikko Salomaa Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer\'s disease: A prospective study in eight cohorts published pages: 723-733, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.01.003	Alzheimer\'s & Dementia 14/6	2019-10-04
2018	Jean Shin, Shaojie Ma, Edith Hofer, Yash Patel, Gennady Roshchupkin, Andre M Sousa, Xueqiu Jian, Rebecca Gottesmann, Thomas H Mosley, Myriam Fornage, Yasaman Saba, Lukas Pirpamer, Reinhold Schmidt, Helena Schmidt, Bernard Mazoyer, Amaia Carrion-Castillo, Joshua Bis, Shuo Li, Qiong Yang, Michelle Luciano, Sherif Karama, Lindsay Lewis, Mark Bastin, Matthew A Harris, Ian Deary, Joanna M Wardlaw, Markus Scholz, Markus Loeffler, Veronica Witte, Frauke Beyer, Arno Villringer, Hieab HHH Adams, M Arfan Ikrum, William S Kremen, Nathan A Gillespie, the ENIGMA Consortium, Nenad Sestan, Zdenka Pausova, Sudha Seshadri, Tomas Paus, the neuroCHARGE Working Group Planar cell polarity pathway and development of the human visual cortex published pages: , ISSN: , DOI: 10.1101/404558	bioRxiv	2019-10-04
2018	Christina S. Dintica, Anna Marseglia, Debora Rizzuto, Rui Wang, Janina Seubert, David A. Bennett, Weili Xu IMPAIRED OLFACTORY FUNCTION IS ASSOCIATED WITH ACCELERATED COGNITIVE DECLINE AND NEURODEGENERATION IN THE BRAIN published pages: P248-P249, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.06.2395	Alzheimer\'s & Dementia 14/7	2019-10-04
2018	Behnaz Shakersain, Debora Rizzuto, Susanna Larsson, Gerd FaxÃ©n-Irving, Laura Fratiglioni, Wei-Li Xu The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults: A Population-Based Cohort Study published pages: 229, ISSN: 2072-6643, DOI: 10.3390/nu10020229	Nutrients 10/2	2019-10-04
2018	Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten-Jacobs, Anne-Katrin Giese, Sander W. van der Laan, Solveig Gretarsdottir, Christopher D. Anderson, Michael Chong, Hieab H. H. Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M. Bartz, Oscar R. Benavente, Steve Bevan, Giorgio B. Boncoraglio, Robert D. Brown, Adam S. Butterworth, Caty Carrera, Cara L. Carty, Daniel I. Chasman, Wei-Min Chen, John W. Cole, Adolfo Correa, Ioana Cotlarciuc, Carlos Cruchaga, John Danesh, Paul I. W. de Bakker, Anita L. DeStefano, Marcel den Hoed, Qing Duan, Stefan T. Engelter, Guido J. Falcone, Rebecca F. Gottesman, Raji P. Grewal, Vilmundur Gudnason, Stefan Gustafsson, Jeffrey Haessler, Tamara B. Harris, Ahamad Hassan, Aki S. Havulinna, Susan R. Heckbert, Elizabeth G. Holliday, George Howard, Fang-Chi Hsu, Hyacinth I. Hyacinth, M. Arfan Ikram, Erik Ingelsson, Marguerite R. Irvin, Xueqiu Jian, Jordi JimÃ©nez-Conde, Julie A. Johnson, J. Wouter Jukema, Masahiro Kanai, Keith L. Keene, Brett M. Kissela, Dawn O. Kleindorfer, Charles Kooperberg, Michiaki Kubo, Leslie A. Lange, Carl D. Langefeld, Claudia Langenberg, Lenore J. Launer, Jin-Moo Lee, Robin Lemmens, Didier Leys, Cathryn M. Lewis, Wei-Yu Lin, Arne G. Lindgren, Erik Lorentzen, Patrik K. Magnusson, Jane Maguire, Ani Manichaikul, Patrick F. McArdle, James F. Meschia, Braxton D. Mitchell, Thomas H. Mosley, Michael A. Nalls, Toshiharu Ninomiya, Martin J. Oâ€™Donnell, Bruce M. Psaty, Sara L. Pulit, Kristiina RannikmÃ¤e, Alexander P. Reiner, Kathryn M. Rexrode, Kenneth Rice, Stephen S. Rich, Paul M. Ridker, Natalia S. Rost, Peter M. Rothwell, Jerome I. Rotter, Tatjana Rundek, Ralph L. Sacco, Saori Sakaue, Michele M. Sale, Veikko Salomaa, Bishwa R. Sapkota, Reinhold Schmidt, Carsten O. Schmidt, Ulf Schminke, Pankaj Sharma, Agnieszka Slowik, Cathie L. M. Sudlow, Christian Tanislav, Turgut Tatlisumak, Kent D. Taylor, Vincent N. S. Thijs, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Steffen Tiedt, Stella Trompet, Christophe Tzourio, Cornelia M. van Duijn, Matthew Walters, Nicholas J. Wareham, Sylvia Wassertheil-Smoller, James G. Wilson, Kerri L. Wiggins, Qiong Yang, Salim Yusuf, Joshua C. Bis, Tomi Pastinen, Arno Ruusalepp, Eric E. Schadt, Simon Koplev, Johan L. M. BjÃ¶rkegren, Veronica Codoni, Mete Civelek, Nicholas L. Smith, David A. TrÃ©gouÃ«t, Ingrid E. Christophersen, Carolina Roselli, Steven A. Lubitz, Patrick T. Ellinor, E. Shyong Tai, Jaspal S. Kooner, Norihiro Kato, Jiang He, Pim van der Harst, Paul Elliott, John C. Chambers, Fumihiko Takeuchi, Andrew D. Johnson, Dharambir K. Sanghera, Olle Melander, Christina Jern, Daniel Strbian, Israel Fernandez-Cadenas, W. T. Longstreth, Arndt Rolfs, Jun Hata, Daniel Woo, Jonathan Rosand, Guillaume Pare, Jemma C. Hopewell, Danish Saleheen, Kari Stefansson, Bradford B. Worrall, Steven J. Kittner, Sudha Seshadri, Myriam Fornage, Hugh S. Markus, Joanna M. M. Howson, Yoichiro Kamatani, Stephanie Debette, Martin Dichgans, Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten-Jacobs, Anne-Katrin Giese, Sander W. van der Laan, Solveig Gretarsdottir, Christopher D. Anderson, Michael Chong, Hieab H. H. Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M. Bartz, Oscar R. Benavente, Steve Bevan, Giorgio B. Boncoraglio, Robert D. Brown, Adam S. Butterworth, Caty Carrera, Cara L. Carty, Daniel I. Chasman, Wei-Min Chen, John W. Cole, Adolfo Correa, Ioana Cotlarciuc, Carlos Cruchaga, John Danesh, Paul I. W. de Bakker, Anita L. DeStefano, Marcel den Hoed, Qing Duan, Stefan T. Engelter, Guido J. Falcone, Rebecca F. Gottesman, Raji P. Grewal, Vilmundur Gudnason, Stefan Gustafsson, Jeffrey Haessler, Tamara B. Harris, Ahamad Hassan, Aki S. Havulinna, Susan R. Heckbert, Elizabeth G. Holliday, George Howard, Fang-Chi Hsu, Hyacinth I. Hyacinth, M. Arfan Ikram, Erik Ingelsson, Marguerite R. Irvin, Xueqiu Jian, Jordi Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes published pages: 524-537, ISSN: 1061-4036, DOI: 10.1038/s41588-018-0058-3	Nature Genetics 50/4	2019-10-04
1550	Susanna C Larsson, Matthew Traylor, Rainer Malik, Martin Dichgans, Stephen Burgess, Hugh S Markus Modifiable pathways in Alzheimerâ€™s disease: Mendelian randomisation analysis published pages: j5375, ISSN: 0959-8138, DOI: 10.1136/bmj.j5375	BMJ	2019-10-04
2018	Dina Vojinovic, Sven J. van der Lee, Cornelia M. van Duijn, Meike W. Vernooij, Maryam Kavousi, Najaf Amin, AyÅŸe Demirkan, M. Arfan Ikram, Aad van der Lugt, Daniel Bos Metabolic profiling of intra- and extracranial carotid artery atherosclerosis published pages: 60-65, ISSN: 0021-9150, DOI: 10.1016/j.atherosclerosis.2018.03.015	Atherosclerosis 272	2019-10-04
2018	Rainer Malik, Martin Dichgans Challenges and opportunities in stroke genetics published pages: , ISSN: 0008-6363, DOI: 10.1093/cvr/cvy068	Cardiovascular Research	2019-10-04
2018	Edith Hofer, Gennady V Roshchupkin, Hieab Adams, Maria Knol, Honghuang Lin, Shuo Li, Habil Zare, Shahzad Ahmad, Nicola Armstrong, Claudia Satizabal, Manon Bernard, Joshua Bis, Nathan Gillespie, Michelle Luciano, Aniket Mishra, Markus Scholz, View ORCID ProfileAlexander Teumer, Rui Xia, Xueqiu Jian, Thomas Mosley, Yasaman Saba, Lukas Pirpamer, Stephan Seiler, James Becker, Owen Carmichael, Jerome Rotter, Bruce Psaty, Oscar Lopez, Najaf Amin, Sven Lee, Qiong Yang, Jayandra Himali, Pauline Maillard, Alexa Beiser, Charles DeCarli, Sherif Karama, Lindsay Lewis, Mark Bastin, Mat Harris, Ian Deary, Veronica Witte, Frauke Beyer, Markus Loeffler, Karen Mather, View ORCID ProfilePeter Schofield, Anbupalam Thalamuthu, View ORCID ProfileJohn Kwok, Margaret Wright, David Ames, Julian Trollor, Jiyang Jiang, Henry Brodaty, Wei Wen, Meike Vernooij, Albert Hofman, Andre Uitterlinden, Wiro Niessen, Katharina Wittfeld, Robin Bulow, Uwe Volker, Zdenka Pausova, Bruce Pike, Sophie Maingault, Fabrice Crivello, View ORCID ProfileChristophe Tzourio, Philippe Amouyel, Bernard Mazoyer, Michael Neale, Carol Franz, Michael Lyons, Matthew Panizzon, Ole Andreassen, Anders Dale, Mark Logue, Katrina Grasby, Neda Jahanshad, Jodie Painter, Lucia Colodro-Conde, Janita Bralten, Derrek Hibar, Penelope Lind, Fabrizio Pizzagalli, Jason Stein, Paul Thompson, Sarah Medland, Perminder Sachdev, William Kremen, Joanna Wardlaw, Arno Villringer, Cornelia Duijn, View ORCID ProfileHans Grabe, William Longstreth, Myriam Fornage, Tomas Paus, Stephanie Debette, Arfan Ikram, Helena Schmidt, Reinhold Schmidt, Sudha Seshadri Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium published pages: , ISSN: , DOI: 10.1101/409649	bioRxiv	2019-10-04
2018	Behnaz Shakersain, Debora Rizzuto, Hui-Xin Wang, Gerd FaxÃ©n-Irving, Federica Prinelli, Laura Fratiglioni, Weili Xu An Active Lifestyle Reinforces the Effect of a Healthy Diet on Cognitive Function: A Population-Based Longitudinal Study published pages: 1297, ISSN: 2072-6643, DOI: 10.3390/nu10091297	Nutrients 10/9	2019-10-04
2018	Thom S. Lysen, Frank J. Wolters, Annemarie I. Luik, M. Kamran Ikram, Henning Tiemeier, M. Arfan Ikram Subjective Sleep Quality is not Associated with Incident Dementia: The Rotterdam Study published pages: 239-247, ISSN: 1387-2877, DOI: 10.3233/jad-180055	Journal of Alzheimer\'s Disease 64/1	2019-10-04
2018	Steffen Tiedt, Marco Duering, Christian Barro, Asli Gizem Kaya, Julia Boeck, Felix J. Bode, Matthias Klein, Franziska Dorn, Benno Gesierich, Lars Kellert, Birgit Ertl-Wagner, Michael W. Goertler, Gabor C. Petzold, Jens Kuhle, Frank A. Wollenweber, Nils Peters, Martin Dichgans Serum neurofilament light published pages: e1338-e1347, ISSN: 0028-3878, DOI: 10.1212/wnl.0000000000006282	Neurology 91/14	2019-10-04
2017	Martin Dichgans, Didier Leys Vascular Cognitive Impairment published pages: 573-591, ISSN: 0009-7330, DOI: 10.1161/circresaha.116.308426	Circulation Research 120/3	2019-10-04
2018	Nienke R. Wevers, Dhanesh G. Kasi, Taylor Gray, Karlijn J. Wilschut, Benjamin Smith, Remko van Vught, Fumitaka Shimizu, Yasuteru Sano, Takashi Kanda, Graham Marsh, Sebastiaan J. Trietsch, Paul Vulto, HenriÃ«tte L. Lanz, Birgit Obermeier A perfused human bloodâ€“brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport published pages: , ISSN: 2045-8118, DOI: 10.1186/s12987-018-0108-3	Fluids and Barriers of the CNS 15/1	2019-10-04
2018	Shahzad Ahmad, Christian Bannister, Sven J. van der Lee, Dina Vojinovic, Hieab H.H. Adams, Alfredo Ramirez, Valentina Escott-Price, Rebecca Sims, Emily Baker, Julie Williams, Peter Holmans, Meike W. Vernooij, M. Arfan Ikram, Najaf Amin, Cornelia M. van Duijn Disentangling the biological pathways involved in early features of Alzheimer\'s disease in the Rotterdam Study published pages: 848-857, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2018.01.005	Alzheimer\'s & Dementia 14/7	2019-10-04
2018	Claudia Tamar Silva, Irina V. Zorkoltseva, Maartje N. Niemeijer, Marten E. van den Berg, Najaf Amin, AyÅŸe Demirkan, Elisa van Leeuwen, Adriana I. Iglesias, Laura B. PiÃ±eros-HernÃ¡ndez, Carlos M. Restrepo, Jan A. Kors, Anatoly V. Kirichenko, Rob Willemsen, Ben A. Oostra, Bruno H. Stricker, AndrÃ© G. Uitterlinden, Tatiana I. Axenovich, Cornelia M. van Duijn, Aaron Isaacs A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy published pages: , ISSN: 1755-8794, DOI: 10.1186/s12920-018-0339-9	BMC Medical Genomics 11/1	2019-10-04
2018	Katherine M. Crawford, Cristina Gallego-Fabrega, Christina Kourkoulis, Laura Miyares, Sandro Marini, Jason Flannick, Noel P. Burtt, Marcin von Grotthuss, Benjamin Alexander, Maria C. Costanzo, Neil H. Vaishnav, Rainer Malik, Jennifer L. Hall, Michael Chong, Jonathan Rosand, Guido J. Falcone Cerebrovascular Disease Knowledge Portal published pages: 470-475, ISSN: 0039-2499, DOI: 10.1161/strokeaha.117.018922	Stroke 49/2	2019-10-04
2018	Camille Noirot, Ismini Mainta, Aline Mendes, Paulina Andryszak, Hishayine Visvaratnam, Paul G. Unschuld, Giovanni B. Frisoni, Valentina Garibotto Tau PET imaging evidence in patients with cognitive impairment: preparing for clinical use published pages: 471-482, ISSN: 2281-5872, DOI: 10.1007/s40336-018-0297-4	Clinical and Translational Imaging 6/6	2019-10-04
2018	Anna Marseglia, Weili Xu, Laura Fratiglioni, Cristina Fabbri, Agnes A. M. Berendsen, Agata Bialecka-Debek, Amy Jennings, Rachel Gillings, Nathalie Meunier, Elodie Caumon, Susan Fairweather-Tait, Barbara Pietruszka, Lisette C. P. G. M. De Groot, Aurelia Santoro, Claudio Franceschi Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial published pages: , ISSN: 1664-042X, DOI: 10.3389/fphys.2018.00349	Frontiers in Physiology 9	2019-10-04
2018	Rui Wang, Anna Laveskog, Erika J. Laukka, GrÃ©goria Kalpouzos, Lars BÃ¤ckman, Laura Fratiglioni, Chengxuan Qiu MRI load of cerebral microvascular lesions and neurodegeneration, cognitive decline, and dementia published pages: 1, ISSN: 0028-3878, DOI: 10.1212/wnl.0000000000006355	Neurology	2019-10-04
2018	Sven J van der Lee, Frank J Wolters, M Kamran Ikram, Albert Hofman, M Arfan Ikram, Najaf Amin, Cornelia M van Duijn The effect of APOE and other common genetic variants on the onset of Alzheimer\'s disease and dementia: a community-based cohort study published pages: 434-444, ISSN: 1474-4422, DOI: 10.1016/s1474-4422(18)30053-x	The Lancet Neurology 17/5	2019-10-04
2018	Brian W. Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C. Bis, Adam C. Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alex Amlie-Wolf, Celine Bellenguez, Aura Frizatti, Vincent Chouraki, Alzheimer\'s Disease Genetics Consortium (ADGC), European Alzheimer\'s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in Alzheimer\'s Disease Consortium (GERAD/PERADES), Helena Schmidt, Hakon Hakonarson, Ron Munger, Reinhold Schmidt, Lindsay A. Farrer, Christine Van Broeckhoven, Michael C. O\'Donovan, Anita L. Destefano, Lesley Jones, Jonathan L. Haines, Jean-Francois Deleuze, Michael J. Owen, Vilmundur Gudnason, Richard P. Mayeux, Valentina Escott-Price, Bruce M. Psaty, Agustin Ruiz, Alfredo Ramirez, Li-San Wang, Cornelia M. van Duijn, Peter A. Holmans, Sudha Seshadri, Julie Williams, Philippe Amouyel, Gerard D. Schellenberg, Jean-Charles Lambert, Margaret A. Pericak-Vance Meta-analysis of genetic association with diagnosed Alzheimer\'s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing published pages: , ISSN: , DOI: 10.1101/294629	bioRxiv	2019-10-04
2018	Sven J. van der Lee, Charlotte E. Teunissen, RenÃ© Pool, Martin J. Shipley, Alexander Teumer, Vincent Chouraki, Debora Melo van Lent, Juho Tynkkynen, Krista Fischer, Jussi Hernesniemi, Toomas Haller, Archana Singh-Manoux, Aswin Verhoeven, Gonneke Willemsen, Francisca A. de Leeuw, Holger Wagner, Jenny van Dongen, Johannes Hertel, Kathrin Budde, Ko Willems van Dijk, Leonie Weinhold, M. Arfan Ikram, Maik Pietzner, Markus Perola, Michael Wagner, Nele Friedrich, P. Eline Slagboom, Philip Scheltens, Qiong Yang, Robert E. Gertzen, Sarah Egert, Shuo Li, Thomas Hankemeier, Catharina E.M. van Beijsterveldt, Ramachandran S. Vasan, Wolfgang Maier, Carel F.W. Peeters, Hans JÃ¶rgen Grabe, Alfredo Ramirez, Sudha Seshadri, Andres Metspalu, Mika KivimÃ¤ki, Veikko Salomaa, AyÅŸe Demirkan, Dorret I. Boomsma, Wiesje M. van der Flier, Najaf Amin, Cornelia M. van Duijn Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies published pages: 707-722, ISSN: 1552-5260, DOI: 10.1016/j.jalz.2017.11.012	Alzheimer\'s & Dementia 14/6	2019-10-04
2018	Tavia E. Evans, Hieab H.H. Adams, Silvan Licher, Frank J. Wolters, Aad van der Lugt, M. Kamran Ikram, Michael J. O\'Sullivan, Meike W. Vernooij, M. Arfan Ikram Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia published pages: 129-135, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2018.05.041	NeuroImage 178	2019-10-04
2017	Francisca A. de Leeuw, Carel F.W. Peeters, Maartje I. Kester, Amy C. Harms, Eduard A. Struys, Thomas Hankemeier, Herman W.T. van Vlijmen, Sven J. van der Lee, Cornelia M. van Duijn, Philip Scheltens, AyÅŸe Demirkan, Mark A. van de Wiel, Wiesje M. van der Flier, Charlotte E. Teunissen Blood-based metabolic signatures in Alzheimer\'s disease published pages: 196-207, ISSN: 2352-8729, DOI: 10.1016/j.dadm.2017.07.006	Alzheimer\'s & Dementia: Diagnosis, Assessment & Disease Monitoring 8	2019-10-04
2017	RannikmÃ¤e, K.; Sivakumaran, V.; Millar, H.; Malik, R.; Anderson, C.D.; Chong, M.; Dave, T.; Falcone, G.J.; Fernandez-Cadenas, I.; Jimenez-Conde, J.; Lindgren, A.; Montaner, J.; O\'Donnell, M.; ParÃ©, G.; Radmanesh, F.; Rost, N.S.; Slowik, A.; SÃ¶derholm, M.; Traylor, M.; Pulit, S.L.; Seshadri, S.; Worrall, B.B.; Woo, D.; Markus, H.S.; Mitchell, B.D.; Dichgans, M.; Rosand, J.; Sudlow, CLM; Stroke Genetics Network (SiGN); METASTROKE Collaboration; International Stroke Genetics Consortium (ISGC) COL4A2 is associated with lacunar ischemic stroke and deep ICH: meta-analyses among 21,500 cases and 40,600 controls published pages: , ISSN: 0028-3878, DOI: 10.1212/wnl.0000000000004560	Neurology 1	2019-10-04
2018	Christina S. Dintica, Debora Rizzuto, Anna Marseglia, GrÃ©goria Kalpouzos, Anna-Karin Welmer, Inger WÃ¥rdh, Lars BÃ¤ckman, Weili Xu Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study published pages: 23-30, ISSN: 0197-4580, DOI: 10.1016/j.neurobiolaging.2018.03.003	Neurobiology of Aging 67	2019-10-04
2018	Frank J. Wolters, Johan Boender, Paul S. de Vries, Michelle A. Sonneveld, Peter J. Koudstaal, Moniek P. de Maat, Oscar H. Franco, M. Kamran Ikram, Frank W. Leebeek, M. Arfan Ikram Von Willebrand factor and ADAMTS13 activity in relation to risk of dementia: a population-based study published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-23865-7	Scientific Reports 8/1	2019-10-04
2017	Vasudev Kantae, Shinji Ogino, Marek Noga, Amy C. Harms, Robin M. van Dongen, Gerrit L. J. Onderwater, Arn M. J. M. van den Maagdenberg, Gisela M. Terwindt, Mario van der Stelt, Michel D. Ferrari, Thomas Hankemeier Quantitative profiling of endocannabinoids and related N -acylethanolamines in human CSF using nano LC-MS/MS published pages: 615-624, ISSN: 0022-2275, DOI: 10.1194/jlr.d070433	Journal of Lipid Research 58/3	2019-10-04

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "COSTREAM" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "COSTREAM" are provided by the European Opendata Portal: CORDIS opendata.