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CHEM2NATURE

Enabling precision chemical methodologies applied to natural-based systems for the development of multifunctional biomedical devices

Total Cost €

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EC-Contrib. €

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Partnership

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 CHEM2NATURE project word cloud

Explore the words cloud of the CHEM2NATURE project. It provides you a very rough idea of what is the project "CHEM2NATURE" about.

amenable    performing    countries    organisation    combat    stimuli    regarding    senior    national    scientific    lasting    quality    property    added    drug    origin    preparation    limitations    uavr    accelerate    professionals    polymers    competence    specialized    actions    surface    precision    generation    events    responsiveness    international    chem2nature    cell    technologies    capability    train    expertise    establishment    biomaterials    modification    competitive    clinical    introducing    timeframe    network    performance    natural    living    chemical    publications    joint    innovative    regional    scope    instructive    latter    economic    multifunctionality    exchange    translational    world    proposes    healthcare    uminho    asian    biopolymer    contacts    chemistry    adaptive    comprise    routes    bioactivity    diagnosis    intellectual    endorse    modifications    cellular    training    ongoing    staff    giving    limited    qualified    therapies    lines    outputs   

Project "CHEM2NATURE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDADE DO MINHO 

Organization address
address: LARGO DO PACO
city: BRAGA
postcode: 4704 553
website: www.uminho.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website http://chem2nature.eu/
 Total cost 1˙007˙453 €
 EC max contribution 1˙007˙453 € (100%)
 Programme 1. H2020-EU.4.b. (Twinning of research institutions)
 Code Call H2020-TWINN-2015
 Funding Scheme CSA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDADE DO MINHO PT (BRAGA) coordinator 539˙993.00
2    UNIVERSIDADE DE AVEIRO PT (AVEIRO) participant 203˙717.00
3    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 134˙496.00
4    THE UNIVERSITY OF WARWICK UK (COVENTRY) participant 129˙246.00
5    KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY KR (DAEJEON) participant 0.00

Map

 Project objective

CHEM2NATURE addresses current limitations of UMINHO in the Chemistry field regarding its scientific know-how and partnerships with world-leading institutions. UMINHO seeks to improve the multifunctionality of natural-origin polymers, often with limited bioactivity and stimuli-responsiveness, and increase the performance of cell-based therapies. Introducing such properties by precision chemical modifications would allow the development of added-value products with instructive and adaptive properties for cellular response control, drug delivery and diagnosis. The main goal of CHEM2NATURE is to combat UMINHO’s limited knowledge, expertise and experience on advanced chemical routes for biopolymer, biomaterials and “living” surface modification. To this aim, an international training and scientific network will be established to accelerate the generation of technologies amenable to be used in the production of innovative healthcare devices. The capability of UMINHO to train highly-qualified researchers and staff would greatly increase, giving rise to a new generation of specialized professionals with scientific/translational competence. The consortium will comprise UMINHO, UAVR and 3 international competitive institutions in Chemistry: 2 European and 1 Asian. The latter will improve UMINHO’s know-how in the translational/clinical fields and raise opportunities to establish new contacts with high-performing and Emerging Asian countries. CHEM2NATURE proposes the joint organisation of events and short-term exchange of senior researchers and staff, aiming at training actions and execution of scientific work in the scope of ongoing scientific projects. Outputs include the increase of number and quality of scientific publications, intellectual property and regional-to-national economic development. CHEM2NATURE will endorse the establishment of a long-lasting consortium beyond the project timeframe for the preparation of new scientific projects and research lines in UMINHO.

 Deliverables

List of deliverables.
D5.5 Scientific publications in international peer-reviewed scientific journals (Month 24) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D5.3 Open days sessions to the general public (Month 24) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D4.1 Request for a special issue in an ISI-indexed international journal – “Engineering and chemical principles in cells encapsulation” (Month 36) Other 2019-09-09 14:57:41
D5.4 Press releases, project brochures, newsletters and web magazines (Month 36) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D3.1 Request for a special issue in an ISI-indexed international journal – “Precision chemical modification of surfaces” (Month 24) Other 2019-09-09 14:57:41
D5.2 Project website and collaborative network establishment (Month 4) Websites, patent fillings, videos etc. 2019-09-09 14:57:39
D5.3 Open days sessions to the general public (Month 12) Websites, patent fillings, videos etc. 2019-09-09 14:57:39
D5.5 Scientific publications in international peer-reviewed scientific journals (Month 12) Websites, patent fillings, videos etc. 2019-09-09 14:57:39
D5.4 Press releases, project brochures, newsletters and web magazines (Month 12) Websites, patent fillings, videos etc. 2019-09-09 14:57:39
D2.1 Request for a special issue in an ISI-indexed international journal – “Chemical strategies for the modification of natural origin materials” (Month 11) Other 2019-09-09 14:57:39
D5.1 Publications record of the coordinator organisation on the Participant Portal (Month 2) Websites, patent fillings, videos etc. 2019-09-09 14:57:39
D5.5 Scientific publications in international peer-reviewed scientific journals (Month 36) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D5.7 Book on “advanced chemical modifications on natural systems” (Month 36) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D5.6 Patent filling (Month 30) Websites, patent fillings, videos etc. 2019-09-09 14:57:41
D5.4 Press releases, project brochures, newsletters and web magazines (Month 24) Websites, patent fillings, videos etc. 2019-09-09 14:57:41

Take a look to the deliverables list in detail:  detailed list of CHEM2NATURE deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Sara Amorim, Diana Soares da Costa, Daniela Freitas, Celso A. Reis, Rui L. Reis, Iva Pashkuleva, Ricardo A. Pires
Molecular weight of surface immobilized hyaluronic acid influences CD44-mediated binding of gastric cancer cells
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-34445-0
Scientific Reports 8/1 2019-09-09
2017 Carla Silva, Agatha Carretero, Diana Soares da Costa, Rui L. Reis, Ramon Novoa-Carballal, Iva Pashkuleva
Design of protein delivery systems by mimicking extracellular mechanisms for protection of growth factors
published pages: 283-293, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.08.042
Acta Biomaterialia 63 2019-09-09
2018 Olesia Dudik, Isabel Leonor, Joana R. Xavier, Hans Tore Rapp, Ricardo A. Pires, Tiago H. Silva, Rui L. Reis
Sponge-derived silica for tissue regeneration
published pages: 577-578, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2018.03.025
Materials Today 21/5 2019-09-09
2018 Ramon Novoa-Carballal, Agatha Carretero, Raul Pacheco, Rui L. Reis, Iva Pashkuleva
Star-Like Glycosaminoglycans with Superior Bioactivity Assemble with Proteins into Microfibers
published pages: 14341-14345, ISSN: 0947-6539, DOI: 10.1002/chem.201802243
Chemistry - A European Journal 24/54 2019-09-09
2018 Rui R. Costa, Miguel González-Pérez, Marcos Herrero-Gutiérrez, Ricardo A. Pires, Matilde Alonso, J. Carlos Rodriguez-Cabello, Rui L. Reis, Iva Pashkuleva
Tuning the Stiffness of Surfaces by Assembling Genetically Engineered Polypeptides with Tailored Amino Acid Sequence
published pages: 3401-3411, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.8b00723
Biomacromolecules 19/8 2019-09-09
2017 Rami Mhanna, Jana Becher, Matthias Schnabelrauch, Rui L. Reis, Iva Pashkuleva
Sulfated Alginate as a Mimic of Sulfated Glycosaminoglycans: Binding of Growth Factors and Effect on Stem Cell Behavior
published pages: 1700043, ISSN: 2366-7478, DOI: 10.1002/adbi.201700043
Advanced Biosystems 1/7 2019-09-09
2017 João S. Fernandes, Piergiorgio Gentile, Ricardo A. Pires, Rui L. Reis, Paul V. Hatton
Multifunctional bioactive glass and glass-ceramic biomaterials with antibacterial properties for repair and regeneration of bone tissue
published pages: 2-11, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.06.046
Acta Biomaterialia 59 2019-09-09
2018 Ana M. Carvalho, Raquel Teixeira, Ramón Novoa-Carballal, Ricardo A. Pires, Rui L. Reis, Iva Pashkuleva
Redox-Responsive Micellar Nanoparticles from Glycosaminoglycans for CD44 Targeted Drug Delivery
published pages: 2991-2999, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.8b00561
Biomacromolecules 19/7 2019-09-09
2018 Bárbara B. Mendes, Manuel Gómez-Florit, Ricardo A. Pires, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes
Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior
published pages: 17388-17401, ISSN: 2040-3364, DOI: 10.1039/c8nr04273j
Nanoscale 10/36 2019-09-09
2017 A. Carretero, D. Soares da Costa, R. L. Reis, I. Pashkuleva
Extracellular matrix-inspired assembly of glycosaminoglycan–collagen fibers
published pages: 3103-3106, ISSN: 2050-7518, DOI: 10.1039/C7TB00704C
J. Mater. Chem. B 5/17 2019-09-09
2017 João Borges, Maria P. Sousa, Goksu Cinar, Sofia G. Caridade, Mustafa O. Guler, João F. Mano
Nanoengineering Hybrid Supramolecular Multilayered Biomaterials Using Polysaccharides and Self-Assembling Peptide Amphiphiles
published pages: 1605122, ISSN: 1616-301X, DOI: 10.1002/adfm.201605122
Advanced Functional Materials 27/17 2019-09-09
2017 Ivo M. Aroso, Ana R. Araújo, Ricardo A. Pires, Rui L. Reis
Cork: Current Technological Developments and Future Perspectives for this Natural, Renewable, and Sustainable Material
published pages: 11130-11146, ISSN: 2168-0485, DOI: 10.1021/acssuschemeng.7b00751
ACS Sustainable Chemistry & Engineering 5/12 2019-09-09
2019 Alexandra Brito, Yousef M. Abul-Haija, Diana Soares da Costa, Ramon Novoa-Carballal, Rui L. Reis, Rein V. Ulijn, Ricardo A. Pires, Iva Pashkuleva
Minimalistic supramolecular proteoglycan mimics by co-assembly of aromatic peptide and carbohydrate amphiphiles
published pages: 2385-2390, ISSN: 2041-6520, DOI: 10.1039/c8sc04361b
Chemical Science 10/8 2019-09-09
2017 A. Carretero, D. Soares da Costa, R. L. Reis, I. Pashkuleva
Extracellular matrix-inspired assembly of glycosaminoglycan–collagen fibers
published pages: 3103-3106, ISSN: 2050-7518, DOI: 10.1039/C7TB00704C
J. Mater. Chem. B 5/17 2019-09-09

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