#	Pagina
attuale pagina	/open-h2020/projects/200680/index.html
-1	/open-fp7/projects/100203/index.html

Opendata, web and dolomites

VADEMA SIGNED

Doctoral Industrial School for Vaccine Design through Structural Mass Spectrometry

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

VADEMA project word cloud

Explore the words cloud of the VADEMA project. It provides you a very rough idea of what is the project "VADEMA" about.

degree respective efforts portions soluble membrane applicative accessible dynamics spread discovered threatening parts combined antigens strategy host trained phd students leaders recombinant consisting vaccines components forms bearing opportunity reverse immunity alternative academic humoral possibility vaccinology training impossible complemented raised compare rational mass purified microorganisms efficacious spectrometry experimental conformation live devastating antigen successful innovative technologies grow glycoconjugation outcome powerful courses despite structural killed diseases human occasion basic dna empirical life led receive decades opened epitopes previously form attenuated group protective efficient designing immune observation industrial science broadly immunology native infections platform good multiple

Project "VADEMA" data sheet

The following table provides information about the project.

Coordinator	GLAXOSMITHKLINE VACCINES SRL Organization address address: VIA FIORENTINA 1 city: SIENA postcode: 53100 website: www.novartis.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Project website	http://www.vadema.eu/
Total cost	1˙096˙286 €
EC max contribution	1˙096˙286 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2015
Funding Scheme	MSCA-ITN-EID
Starting year	2016
Duration (year-month-day)	from 2016-11-01 to 2020-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	GLAXOSMITHKLINE VACCINES SRL	IT (SIENA)	coordinator	516˙122.00
2	KOBENHAVNS UNIVERSITET	DK (KOBENHAVN)	participant	580˙163.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

Project objective

Vaccines discovered from empirical approaches and consisting in killed, live-attenuated microorganisms or purified components have led to the successful control of many devastating diseases. Several novel technologies, such as recombinant DNA technology, glycoconjugation, reverse vaccinology have opened the possibility of designing vaccines previously considered impossible to make. Despite decades of efforts, vaccines have not yet been developed against several of the most life-threatening infections. Based on the observation that an efficacious immune response only require protective epitopes, structural vaccinology combined with human immunology are therefore rapidly emerging as a powerful alternative strategy for the rational design of vaccines bearing multiple protective epitopes and offering the opportunity of developing broadly effective immunity. The proposal is focused on the development of a Structural Mass Spectrometry platform and its application to compare conformation and dynamics of antigens in their native states (membrane) with their recombinant soluble forms (vaccines) and to get a better understanding of the humoral response raised against the two forms. The outcome of such studies will be to identify antigen portions accessible to the host immune system and those epitopes that can be recognized in the native form of the antigens to design efficient vaccines. Structural Mass Spectrometry is a very new science in Europe and the proposal represents the unique opportunity for 4 PhD students to be trained by an academic and an industrial group, leaders in respective parts of the field. The program will be complemented with a number of training courses. The students will receive a PhD degree in structural mass spectrometry applied to vaccinology. It represents a good occasion to spread this technology in Europe and good opportunities for students that are willing to grow both in basic science as well as innovative and applicative experimental research.

Deliverables

List of deliverables.
Recruitment	Other	2019-03-20 15:38:37
Supervisory Board	Other	2019-03-25 10:34:34

Take a look to the deliverables list in detail: detailed list of VADEMA deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "VADEMA" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "VADEMA" are provided by the European Opendata Portal: CORDIS opendata.